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Last Updated: November 5, 2024

CLINICAL TRIALS PROFILE FOR TRIENTINE TETRAHYDROCHLORIDE


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All Clinical Trials for trientine tetrahydrochloride

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004339 ↗ Study of Tetrathiomolybdate in Patients With Wilson Disease Completed University of Michigan Phase 3 1994-01-01 OBJECTIVES: Evaluate the safety and efficacy of ammonium tetrathiomolybdate alone and compared with trientine therapy as initial treatment in patients with Wilson disease presenting neurologically.
NCT00004339 ↗ Study of Tetrathiomolybdate in Patients With Wilson Disease Completed National Center for Research Resources (NCRR) Phase 3 1994-01-01 OBJECTIVES: Evaluate the safety and efficacy of ammonium tetrathiomolybdate alone and compared with trientine therapy as initial treatment in patients with Wilson disease presenting neurologically.
NCT00212355 ↗ Efficacy and Safety, Long-term Study of Zinc Acetate to Treat Wilson's Disease in Japan. Completed Nobelpharma Phase 3 2005-03-01 The purpose of this long-term study is to determine whether Zinc Acetate is effective and safe in the treatment of Wilson's disease among Japanese.
NCT01178112 ↗ Trientine and Carboplatin in Advanced Malignancies Completed M.D. Anderson Cancer Center Phase 1 2010-07-01 The goal of this clinical research study is to find the highest tolerable dose of the combination of trientine and carboplatin that can be given to patients with advanced cancer. The safety of this drug combination will also be studied.
NCT01213888 ↗ Trientine Hydrochloride for the Prevention of Macular Edema Associated With Pan-retinal Photocoagulation for Severe Non-proliferative and Proliferative Diabetic Retinopathy Terminated University of British Columbia N/A 2010-11-01 To evaluate the effects of Trientine Hydrochloride in prevention of post-laser (pan-retinal photocoagulation) macular edema in the eyes for subjects with diabetic retinopathy. Trientine hydrochloride can limit secondary inflammatory damage to retinal vessels following the administration of pan-retinal photocoagulation therapy for severe non-proliferative diabetic retinopathy or retinal neovascularization due to diabetic retinopathy, resulting in less macular edema and improved visual outcomes.
NCT01295073 ↗ Trientine Hydrochloride for the Prevention of Macular Edema After Cataract Surgery in Patients With Type 2 Diabetes Mellitus Withdrawn University of British Columbia Phase 2 1969-12-31 The primary purpose of the protocol is to evaluate whether Trientine Hydrochloride, a copper chelator which is an agent that binds with and removes copper, will be effective in minimizing macular edema after cataract surgery in individuals with type 2 diabetes. It is our hypothesis that there will be a reduction in copper-attributed inflammation after surgery resulting a decrease in edema.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for trientine tetrahydrochloride

Condition Name

Condition Name for trientine tetrahydrochloride
Intervention Trials
Wilson Disease 5
Wilson's Disease 3
Advanced Cancers 1
Diabetic Retinopathy 1
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Condition MeSH

Condition MeSH for trientine tetrahydrochloride
Intervention Trials
Hepatolenticular Degeneration 8
Macular Edema 2
Cataract 1
Cardiomyopathy, Hypertrophic 1
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Clinical Trial Locations for trientine tetrahydrochloride

Trials by Country

Trials by Country for trientine tetrahydrochloride
Location Trials
United States 9
United Kingdom 5
Germany 4
Belgium 2
Denmark 2
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Trials by US State

Trials by US State for trientine tetrahydrochloride
Location Trials
Connecticut 3
Texas 2
Michigan 2
California 1
North Carolina 1
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Clinical Trial Progress for trientine tetrahydrochloride

Clinical Trial Phase

Clinical Trial Phase for trientine tetrahydrochloride
Clinical Trial Phase Trials
Phase 4 1
Phase 3 3
Phase 2 3
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Clinical Trial Status

Clinical Trial Status for trientine tetrahydrochloride
Clinical Trial Phase Trials
Completed 6
Active, not recruiting 2
Withdrawn 2
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Clinical Trial Sponsors for trientine tetrahydrochloride

Sponsor Name

Sponsor Name for trientine tetrahydrochloride
Sponsor Trials
Univar BV 3
Orphalan 2
University of British Columbia 2
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Sponsor Type

Sponsor Type for trientine tetrahydrochloride
Sponsor Trials
Industry 11
Other 11
NIH 1
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