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Last Updated: November 7, 2024

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CLINICAL TRIALS PROFILE FOR WEGOVY


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All Clinical Trials for wegovy

Trial ID Title Status Sponsor Phase Start Date Summary
NCT05071898 ↗ Pharmacogenetics of Response to GLP1R Agonists Not yet recruiting University of Maryland, Baltimore Phase 1 2021-12-01 Overweight/obese otherwise healthy volunteers will be recruited from the Old Order Amish population in Lancaster County, PA. Lancaster County, PA. Pharmacodynamic responses to GLP1R agonist will be assessed by conducting frequently sampled intravenous glucose tolerance tests (FSIGT) both before and after semaglutide for six weeks. The proposal proposes two specific aims: 1. Specific Aim #1. To identify genetic variants associated with effects of a GLP1R agonist to enhance glucose-stimulated first phase insulin secretion in the two FSIGTs (before and after administration of drug). 2. Specific Aim #2. To identify genetic variants associated with the effect of a GLP1R agonist to accelerate the rate of glucose disappearance as assessed in the two FSIGTs (before and after administration of drug). Genotyping will be conducted using a high-density array with comprehensive coverage of DNA sequence variants. In addition, the analysis will leverage a global imputation panel generated from 1,025 Amish individuals.
NCT05254314 ↗ Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3) Not yet recruiting National Institute of Allergy and Infectious Diseases (NIAID) Phase 2 2022-05-01 This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with excess body weight. We will test the central hypothesis that semaglutide will improve asthma control and reduce airway inflammation due to direct effects on the respiratory tract in adult asthma associated with obesity.
NCT05254314 ↗ Glucagon-Like Peptide-1 Receptor Agonist in the Treatment of Adult, Obesity-related, Symptomatic Asthma (GATA-3) Not yet recruiting Vanderbilt University Medical Center Phase 2 2022-05-01 This is a randomized placebo-controlled trial of semaglutide, an FDA-approved therapy for the treatment of type 2 diabetes mellitus and obesity, in adults with symptomatic asthma despite the use of inhaled steroids and with excess body weight. We will test the central hypothesis that semaglutide will improve asthma control and reduce airway inflammation due to direct effects on the respiratory tract in adult asthma associated with obesity.
NCT05424003 ↗ Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant Not yet recruiting Novo Nordisk A/S Phase 2 2022-07-01 In this study, semaglutide will be compared to placebo (a look-alike inactive substance, a "sugar pill") to determine if its use will prevent weight gain after liver transplantation (LT). In addition, researchers will be testing to determine if semaglutide prevents the development of Non-Alcoholic Fatty Liver Disease (NAFLD) after transplant through Magnetic Resonance Imaging (MRI) and laboratory results.
NCT05424003 ↗ Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant Not yet recruiting Virginia Commonwealth University Phase 2 2022-07-01 In this study, semaglutide will be compared to placebo (a look-alike inactive substance, a "sugar pill") to determine if its use will prevent weight gain after liver transplantation (LT). In addition, researchers will be testing to determine if semaglutide prevents the development of Non-Alcoholic Fatty Liver Disease (NAFLD) after transplant through Magnetic Resonance Imaging (MRI) and laboratory results.
NCT05548647 ↗ Semaglutide Treatment, Appetite, and Eating Behavior: Long-term Effects Recruiting Novo Nordisk A/S Phase 4 2022-07-26 This study will evaluate the effect of semaglutide on eating behavior, appetite (hunger/fullness), and food liking in the long-term, as compared to placebo. All participants will receive lifestyle modification (diet and exercise) counseling, and will be prescribed the FDA-approved weight loss medication, semaglutide, or placebo (an inactive saline solution) for 72 weeks.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for wegovy

Condition Name

Condition Name for wegovy
Intervention Trials
Obesity 6
NAFLD 2
Non-alcoholic Fatty Liver Disease 2
Interstitial Lung Disease 1
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Condition MeSH

Condition MeSH for wegovy
Intervention Trials
Obesity 5
Non-alcoholic Fatty Liver Disease 2
Liver Diseases 2
Fatty Liver 2
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Clinical Trial Locations for wegovy

Trials by Country

Trials by Country for wegovy
Location Trials
United States 4
Egypt 1
China 1
Canada 1
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Trials by US State

Trials by US State for wegovy
Location Trials
Pennsylvania 2
Virginia 1
Tennessee 1
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Clinical Trial Progress for wegovy

Clinical Trial Phase

Clinical Trial Phase for wegovy
Clinical Trial Phase Trials
Phase 4 5
Phase 2 5
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for wegovy
Clinical Trial Phase Trials
Not yet recruiting 9
Recruiting 3
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Clinical Trial Sponsors for wegovy

Sponsor Name

Sponsor Name for wegovy
Sponsor Trials
Novo Nordisk A/S 3
University of Pennsylvania 2
National Institute of Allergy and Infectious Diseases (NIAID) 1
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Sponsor Type

Sponsor Type for wegovy
Sponsor Trials
Other 12
Industry 5
NIH 1
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