CLINICAL TRIALS PROFILE FOR WELIREG
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All Clinical Trials for welireg
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT03634540 ↗ | A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003) | Recruiting | Peloton Therapeutics, Inc. | Phase 2 | 2018-09-27 | This is an open-label Phase 2 study which will evaluate the efficacy and safety of belzutifan in combination with cabozantinib in participants with advanced ccRCC. Belzutifan and cabozantinib will be administered orally once daily. |
| NCT04994522 ↗ | A Study of Belzutifan (MK-6482) in Participants With Renal Impairment (MK-6482-021) | Not yet recruiting | Merck Sharp & Dohme Corp. | Phase 1 | 2021-12-06 | The primary purpose of this study is to compare the plasma pharmacokinetics (PK) of belzutifan (MK-6482) following a single oral 120 mg dose in participants with end stage renal disease (ESRD) before and after hemodialysis (HD) to each other and also to that of healthy matched control participants. This study will also evaluate the safety and tolerability of a single oral 120 mg dose of belzutifan in participants with ESRD and the extent of belzutifan removed by HD. |
| NCT04995484 ↗ | Belzutifan (MK-6482) Hepatic Impairment Study (MK-6482-020) | Not yet recruiting | Merck Sharp & Dohme Corp. | Phase 1 | 2021-12-06 | The primary purpose of this study is to compare the plasma pharmacokinetics (PK) of belzutifan (MK-6482) following a single oral 120 mg dose of belzutifan in participants with moderate hepatic impairment to that of healthy matched control participants. This study will also evaluate the safety and tolerability of a single oral 120 mg dose of belzutifan in participants with moderate hepatic impairment. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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