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Last Updated: November 22, 2024

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CLINICAL TRIALS PROFILE FOR XPOVIO

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All Clinical Trials for xpovio

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01607905 ↗	Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer	Completed	Karyopharm Therapeutics Inc	Phase 1	2012-06-18	Phase 1 study to evaluate the safety and tolerability of selinexor and determine the Recommended Phase 2 Dose (RP2D) of selinexor for advanced or metastatic solid tumor malignancies.
NCT01607905 ↗	Safety Study of KPT-330 (Selinexor) in Patients With Advanced or Metastatic Solid Tumor Cancer	Completed	Karyopharm Therapeutics, Inc	Phase 1	2012-06-18	Phase 1 study to evaluate the safety and tolerability of selinexor and determine the Recommended Phase 2 Dose (RP2D) of selinexor for advanced or metastatic solid tumor malignancies.
NCT02025985 ↗	Study of KPT-330 (Selinexor) in Female Patients With Advanced Gynaecologic Malignancies	Completed	Karyopharm Therapeutics Inc	Phase 2	2014-04-09	The primary trial objective is to determine the efficacy of KPT-330 (selinexor) in participants with advanced or metastatic gynaecological cancers by disease control rate (complete response (CR) or partial response (PR) or stable disease (SD) for at least 12 weeks, assessed according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1.
NCT02025985 ↗	Study of KPT-330 (Selinexor) in Female Patients With Advanced Gynaecologic Malignancies	Completed	Karyopharm Therapeutics, Inc	Phase 2	2014-04-09	The primary trial objective is to determine the efficacy of KPT-330 (selinexor) in participants with advanced or metastatic gynaecological cancers by disease control rate (complete response (CR) or partial response (PR) or stable disease (SD) for at least 12 weeks, assessed according to Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for xpovio

Condition Name

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Condition Name for xpovio
Intervention	Trials
Multiple Myeloma	4
Refractory Plasma Cell Myeloma	2
Coronavirus Infection	2
Malignant Glioma	2
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Condition MeSH

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Condition MeSH for xpovio
Intervention	Trials
Neoplasms, Plasma Cell	9
Multiple Myeloma	9
Carcinoma	4
Glioblastoma	3
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Clinical Trial Locations for xpovio

Trials by Country

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Trials by Country for xpovio
Location	Trials
United States	79
Greece	4
China	3
Denmark	3
Israel	2
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Trials by US State

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Trials by US State for xpovio
Location	Trials
New York	7
California	6
Florida	6
Texas	5
Minnesota	4
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Clinical Trial Progress for xpovio

Clinical Trial Phase

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Clinical Trial Phase for xpovio
Clinical Trial Phase	Trials
Phase 2	13
Phase 1/Phase 2	6
Phase 1	5
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Clinical Trial Status

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Clinical Trial Status for xpovio
Clinical Trial Phase	Trials
Recruiting	13
Not yet recruiting	7
Completed	3
[disabled in preview]	1
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Clinical Trial Sponsors for xpovio

Sponsor Name

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Sponsor Name for xpovio
Sponsor	Trials
Karyopharm Therapeutics Inc	13
National Cancer Institute (NCI)	11
Karyopharm Therapeutics, Inc	3
[disabled in preview]	2
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Sponsor Type

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Sponsor Type for xpovio
Sponsor	Trials
Industry	19
Other	14
NIH	11
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