Vitamin C Drug Class List

Drugs in Drug Class: Vitamin C

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Mcguff	ASCOR	ascorbic acid	SOLUTION;INTRAVENOUS	209112-001	Oct 2, 2017		RX	Yes	Yes
Sandoz Canada Inc	INFUVITE ADULT	alpha-tocopherol acetate; ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin 5'-phosphate sodium; thiamine hydrochloride; vitamin a palmitate; vitamin k	SOLUTION;INTRAVENOUS	021163-001	May 18, 2000		RX	Yes	Yes
Sandoz Canada Inc	INFUVITE ADULT	alpha-tocopherol acetate; ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin 5'-phosphate sodium; thiamine hydrochloride; vitamin a palmitate; vitamin k	SOLUTION;INTRAVENOUS	021163-002	Jun 16, 2003		RX	Yes	Yes
Sandoz Canada Inc	INFUVITE PEDIATRIC	ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid; niacinamide; pyridoxine; riboflavin; thiamine; tocopherol acetate; vitamin a; vitamin k	INJECTABLE;INTRAVENOUS	021265-001	Feb 21, 2001		RX	Yes	Yes
Sandoz Canada Inc	INFUVITE PEDIATRIC (PHARMACY BULK PACKAGE)	ascorbic acid; biotin; cholecalciferol; cyanocobalamin; dexpanthenol; folic acid; niacinamide; pyridoxine; riboflavin; thiamine; tocopherol acetate; vitamin a; vitamin k	INJECTABLE;INTRAVENOUS	021265-002	Jan 29, 2004		RX	Yes	Yes

Vitamin C Market Analysis and Financial Projection

The global Vitamin C market demonstrates robust growth fueled by diverse applications and continuous innovation, while patent activities focus on enhancing stability and bioavailability across formulations. Here's a detailed analysis:

Market Dynamics

Current Valuation and Growth Projections

• The market reached $1.95 billion in 2023 and is projected to grow at a 6% CAGR, surpassing $4.01 billion by 2034[1][5][15].
• Key segments driving growth:
  • Pharmaceuticals: Vitamin C's role in cancer therapy (e.g., trials showing 97% survival rates in leukemia treatments)[3].
  • Cosmetics: Skincare formulations integrating stabilized Vitamin C for anti-aging and brightening (e.g., Amorepacific's award-winning serums)[10].
  • Food & Beverages: Usage as a preservative and nutritional fortifier[3][7].

Regional Trends

• North America dominates (45% market share), with the U.S. market expected to reach $1.4 billion by 2034[5][15].
• Asia-Pacific emerges as a fast-growing region, led by China's expanding middle class and healthcare investments[5][15].

Key Drivers

• Rising health consciousness post-pandemic.
• Increasing demand for dietary supplements and functional foods[1][7].
• Expansion of dermocosmetics and pharmaceutical applications[6][10].

Challenges

• Price volatility due to raw material costs[1][15].
• Regulatory hurdles and competition from alternative antioxidants[1].

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Patent Landscape

Innovations in Stability and Delivery

• Stabilization Technologies:
  • Unilever's patent combining Vitamin C with olivine extract to enhance skin glow and shelf life[6].
  • Amorepacific's oxygen-blocking formulation for improved oxidation stability in serums[10].
  • Chinese patents (e.g., CN103637995A) using antioxidant blends to prevent tablet discoloration[9].

Bioavailability Enhancements

• Injectable formulations: Ready-to-use ascorbic acid compounds for treating deficiencies (e.g., patents targeting scurvy)[11].
• Lipophilic derivatives: Patents like US20080207748A1 improve cellular absorption and plasma retention[17].

Advanced Manufacturing Methods

• Coated Vitamin C: Growth in pills, capsules, and tablets for controlled release, with DSM and CSPC Pharma leading[8].
• Liquid stability: WO1996022081A1 outlines methods to reduce oxygen exposure in liquid compositions[14].

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Competitive Landscape

Key Players and Strategies

• DSM, CSPC Pharma, and Shandong Luwei focus on coated Vitamin C products for diverse applications[8][17].
• Amorepacific and Unilever leverage patented formulations to capture premium skincare markets[6][10].

Opportunities

• Expansion into emerging markets (e.g., Latin America, Middle East)[15].
• Product differentiation: Investments in nanotechnology and hybrid supplements (e.g., Vitamin C + zinc combinations)[3][7].

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Key Takeaways

• The Vitamin C market is poised for sustained growth, driven by health trends and multifunctional applications.
• Patent activity emphasizes stability, bioavailability, and novel delivery systems, critical for maintaining competitive advantage.
• Regional diversification and regulatory compliance remain pivotal for market players.

"The global vitamin C market is projected to reach USD 4.01 billion by 2034, with innovation in stabilization and delivery methods catalyzing growth." [5][7][10]

References

1. https://www.drugpatentwatch.com/p/drug-price/drugname/VITAMIN+C
2. https://patents.google.com/patent/US6235721B1/en
3. https://market.us/report/ascorbic-acid-market/
4. https://www.treatmentactiongroup.org/wp-content/uploads/2021/11/hcv_tb_longacting_patent_trends.pdf
5. https://www.precedenceresearch.com/vitamin-c-market
6. https://www.cosmeticsdesign-europe.com/Article/2023/04/20/unilever-patents-vitamin-c-olivine-skin-care-formulation-for-energising-glow/
7. https://www.globalinsightservices.com/reports/ascorbic-acid-market/
8. https://www.cognitivemarketresearch.com/coated-vitamin-c-market-report
9. https://patents.google.com/patent/CN103637995A/en
10. https://www.apgroup.com/int/en/news/2020-12-21.html
11. https://patents.justia.com/patent/20230181525
12. https://patents.google.com/patent/CN104146952A/en
13. https://patents.google.com/patent/US4036948A/en
14. https://patents.google.com/patent/WO1996022081A1/en
15. https://marketresearch.biz/report/vitamin-c-market/
16. https://patents.google.com/patent/US20080207748A1/en
17. https://www.openpr.com/news/2844637/vitamin-c-ascorbic-acid-market-2022-report-with-value-chain