Drug Price Trends for ASPIRIN-DIPYRIDAM ER

Average Pharmacy Cost for ASPIRIN-DIPYRIDAM ER

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
ASPIRIN-DIPYRIDAM ER 25-200 MG	16714-0964-01	0.65396	EACH	2025-03-19
ASPIRIN-DIPYRIDAM ER 25-200 MG	43598-0339-60	0.65396	EACH	2025-03-19
ASPIRIN-DIPYRIDAM ER 25-200 MG	49884-0007-02	0.65396	EACH	2025-03-19
ASPIRIN-DIPYRIDAM ER 25-200 MG	42571-0274-60	0.65396	EACH	2025-03-19
ASPIRIN-DIPYRIDAM ER 25-200 MG	68462-0405-60	0.65396	EACH	2025-03-19

Market Analysis and Price Projections for Aspirin-Dipyridamole Extended Release (ER)

Introduction to Aspirin-Dipyridamole ER

Aspirin and extended-release dipyridamole capsules, commonly known by the brand name Aggrenox, are a combination medication used to lower the risk of stroke in individuals who have experienced a transient ischemic attack (TIA) or ischemic stroke. This medication belongs to the class of platelet aggregation inhibitors, which prevent excessive blood clotting.

Market Overview

The global aspirin market, which includes combination aspirin drugs like aspirin-dipyridamole ER, is expected to grow steadily over the next decade. Here are some key market insights:

• Global Aspirin Market Size: The global aspirin market is projected to grow from $2.938 billion in 2024 to $4.236 billion by 2034, at a Compound Annual Growth Rate (CAGR) of 3.8%[3].
• Combination Aspirin Drugs: Combination aspirin drugs, such as aspirin-dipyridamole ER, are leading the market with a share of about 68% in 2023. This segment is expected to display a CAGR of 4.0% through 2034[3].

Key Market Trends

Increasing Prevalence of Chronic Conditions

The rising incidence of chronic conditions such as arthritis, pain, inflammation, renal disorders, cardiovascular diseases, and brain strokes is driving the demand for aspirin and combination aspirin drugs. For instance, chronic pain, especially in adults, is on the rise in the United States due to sedentary lifestyles, further boosting the demand for aspirin[3].

COVID-19 Impact

The COVID-19 pandemic had a mixed impact on the aspirin market. While there were import limitations on active pharmaceutical ingredients, the demand for aspirin surged due to recurring headaches and other symptoms associated with COVID-19[4].

Distribution Channels

The market is segmented into online and offline distribution channels. Offline channels currently hold a significant market share, but online channels are growing rapidly due to increasing internet penetration and consumer preference for online retailing during the pandemic[4].

Price Projections and Cost Analysis

Current Pricing

• The cost for aspirin-dipyridamole ER capsules (25 mg-200 mg) can range from $62.97 for a supply of 20 capsules to $223.10 for a supply of 60 capsules, depending on the pharmacy and the use of discount cards[2][5].

Generic Versions

A generic version of Aggrenox (aspirin-dipyridamole ER) is available, which can significantly reduce the cost for patients. For example, the generic version can cost as low as $62.97 for 20 capsules[2].

Patient Assistance Programs

While there are no specific patient assistance programs (PAPs) for aspirin-dipyridamole ER, programs like Rx Outreach Medications offer discounted prices for eligible patients. For instance, some medications are available for a fee of $20 for up to a 180-day supply[5].

Regional Market Insights

United States

The United States is expected to seize a significant global market share, with a CAGR of 3.9% from 2024 to 2034. The primary driver in this region is the increasing need for aspirin to manage chronic pain, particularly among adults with sedentary lifestyles[3].

Asia Pacific

China is predicted to provide high growth opportunities in the aspirin market, driven by the growing API industry and the increasing prevalence of chronic conditions[3][4].

Safety and Efficacy

Clinical Trials

The ESPS2 study, a 24-month, multicenter, double-blind, randomized trial, compared the efficacy and safety of aspirin and extended-release dipyridamole capsules with placebo, extended-release dipyridamole alone, and aspirin alone. The study found that while the combination therapy was effective, there was no clear benefit in terms of safety over aspirin alone[1].

Adverse Events

The incidence of adverse events leading to discontinuation of treatment was significant, with 25% of patients discontinuing aspirin and extended-release dipyridamole capsules due to adverse events[1].

Market Drivers and Barriers

Market Drivers

• Increasing awareness about myocardial infarction and other cardiovascular diseases.
• Growing demand for antiplatelet agents to prevent excessive blood clotting.
• Expanding retail and e-commerce sales channels[3][4].

Market Barriers

• Potential side effects and adverse events associated with the medication.
• Limited patient assistance programs for this specific medication.
• Stock shortages and pricing variability[1][2][5].

Key Takeaways

• The global aspirin market, including combination aspirin drugs like aspirin-dipyridamole ER, is expected to grow at a CAGR of 3.8% from 2024 to 2034.
• The combination aspirin segment is leading the market with a significant share and growth rate.
• The United States and Asia Pacific regions are key markets driven by the increasing prevalence of chronic conditions.
• Generic versions and patient assistance programs can help reduce the cost for patients.
• Safety and efficacy data from clinical trials highlight the effectiveness but also the potential for adverse events.

Frequently Asked Questions (FAQs)

1. What is the primary use of aspirin-dipyridamole ER capsules?

Aspirin-dipyridamole ER capsules are used to lower the risk of stroke in people who have had a transient ischemic attack (TIA) or ischemic stroke.

2. How much does aspirin-dipyridamole ER typically cost?

The cost can range from $62.97 for 20 capsules to $223.10 for 60 capsules, depending on the pharmacy and the use of discount cards.

3. Are there any patient assistance programs available for aspirin-dipyridamole ER?

While there are no specific PAPs for this medication, programs like Rx Outreach Medications offer discounted prices for eligible patients.

4. What are the common adverse events associated with aspirin-dipyridamole ER?

Common adverse events include those that led to discontinuation of treatment in about 25% of patients, such as gastrointestinal issues and other side effects[1].

5. How is the COVID-19 pandemic impacting the aspirin market?

The pandemic has had a mixed impact, with increased demand due to recurring headaches and other symptoms, but also import limitations on active pharmaceutical ingredients[4].

Cited Sources:

1. DailyMed: Aspirin and Dipyridamole capsule, extended release.
2. Drugs.com: Aspirin/dipyridamole Prices, Coupons, Copay Cards & Patient Assistance.
3. Future Market Insights: Aspirin Drug Market Size, Share & Forecast to 2034.
4. Knowledge Sourcing: Global Aspirin Market Size & Share: Industry Report, 2022-2027.
5. Drugs.com: Aggrenox Prices, Coupons, Copay Cards & Patient Assistance.