Drug Price Trends for LOSARTAN-HYDROCHLOROTHIAZIDE

Average Pharmacy Cost for LOSARTAN-HYDROCHLOROTHIAZIDE

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
LOSARTAN-HYDROCHLOROTHIAZIDE 50-12.5 MG TAB	68180-0215-09	0.07816	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	16714-0224-03	0.09772	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	29300-0191-19	0.09772	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	00093-7369-10	0.09772	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	29300-0191-10	0.09772	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	00093-7369-56	0.09772	EACH	2025-03-19
LOSARTAN-HYDROCHLOROTHIAZIDE 100-12.5 MG TAB	00093-7369-98	0.09772	EACH	2025-03-19

Losartan-Hydrochlorothiazide Market Analysis and Price Projections

Introduction to Losartan-Hydrochlorothiazide

Losartan-hydrochlorothiazide is a combination medication used primarily to treat high blood pressure (hypertension). Losartan is an angiotensin II receptor blocker (ARB), while hydrochlorothiazide is a diuretic. This combination therapy is effective in controlling blood pressure and is commonly prescribed under brand names such as Hyzaar.

Global Market Size and Growth

The global losartan market, which includes losartan-hydrochlorothiazide combinations, is projected to experience significant growth. As of 2024, the global losartan market size was estimated at USD 1625.5 million, with a forecasted expansion to USD 2212.1 million by 2031, at a Compound Annual Growth Rate (CAGR) of 4.50% from 2024 to 2031[1].

Regional Market Dynamics

North America

North America currently dominates the losartan market, holding more than 40% of the global revenue with a market size of USD 650.20 million in 2024. This region is expected to grow at a CAGR of 2.7% from 2024 to 2031. The high prevalence of hypertension and the large elderly population in this region contribute to the robust demand for losartan-hydrochlorothiazide[1].

Europe

Europe holds around 30% of the global revenue, with a market size of USD 487.65 million in 2024. The region is expected to grow at a CAGR of 3.0% from 2024 to 2031. The increasing awareness of cardiovascular health and the availability of healthcare services drive the demand in this region[1].

Asia-Pacific

The Asia-Pacific region is anticipated to show the strongest growth, with a CAGR of 6.5% from 2024 to 2031. This growth is driven by the large population, increasing healthcare expenditure, and rising prevalence of hypertension and other cardiovascular diseases[1][3].

Latin America and Middle East & Africa

Latin America and the Middle East & Africa also contribute to the global market, though to a lesser extent. Latin America held around 5% of the global revenue with a market size of USD 81.28 million in 2024, expected to grow at a CAGR of 3.9%. The Middle East and Africa held around 2% with a market size of USD 32.51 million in 2024, expected to grow at a CAGR of 4.2% from 2024 to 2031[1].

Key Drivers of the Market

Increasing Prevalence of Hypertension

The global prevalence of hypertension is on the rise, particularly among aging populations. This increasing prevalence drives the demand for antihypertensive medications, including losartan-hydrochlorothiazide combinations[1][3].

Growing Adoption of Combination Therapies

Combination therapies like losartan-hydrochlorothiazide improve patient compliance and reduce the risk of medication errors. This has led to increased prescription rates and market share gains for these combination therapies[3].

Technological Advancements

Technological advancements have improved the bioavailability and minimized the side effects of losartan-hydrochlorothiazide tablets, further boosting their adoption[3].

Government Initiatives and Reimbursement Policies

Government initiatives to promote cardiovascular health and favorable reimbursement policies also contribute to the growth of the losartan-hydrochlorothiazide market[3].

Market Segmentation

Application

The market is primarily segmented by application into hypertension and other cardiovascular diseases. Hypertension is the dominant application, driving the majority of the demand for losartan-hydrochlorothiazide[3].

Type

The market is segmented by type into generic and branded formulations. The increasing affordability of generic losartan-hydrochlorothiazide tablets has significantly contributed to market growth[3].

Price Projections

Losartan-Hydrochlorothiazide Prices

The cost for hydrochlorothiazide/losartan oral tablets varies based on the dosage and quantity. For example, a supply of 30 tablets of 12.5 mg-50 mg hydrochlorothiazide/losartan can cost around $27, while a supply of 30 tablets of 12.5 mg-100 mg can cost around $36[2].

Generic vs. Branded

Generic formulations of losartan-hydrochlorothiazide are generally more affordable than branded versions. For instance, the cost for a generic losartan 50 mg oral tablet can be around $12 for a supply of 15 tablets, depending on the pharmacy[5].

Challenges and Restraints

Potential Adverse Effects

Despite the benefits, losartan-hydrochlorothiazide can have potential side effects, which may restrain market growth. These include dizziness, headache, and changes in kidney function[3].

Regulatory Scrutiny and Generic Competition

Regulatory scrutiny and the increasing competition from generic formulations can also pose challenges to the market growth of branded losartan-hydrochlorothiazide tablets[3].

Fluctuating Raw Material Prices

Fluctuations in raw material prices can impact the production costs and profitability of losartan-hydrochlorothiazide manufacturers[3].

Emerging Trends

Development of Once-Daily Formulations

There is a growing trend towards the development of once-daily formulations to enhance patient compliance and convenience[3].

Patient-Centric Drug Design

The focus on patient-centric drug design aims to improve the efficacy and safety of losartan-hydrochlorothiazide tablets, making them more appealing to patients and healthcare providers[3].

Integration of Digital Health Technologies

The integration of digital health technologies, such as medication adherence apps and telehealth services, is expected to further enhance the management of hypertension using losartan-hydrochlorothiazide[3].

Key Takeaways

• The global losartan market, including losartan-hydrochlorothiazide combinations, is expected to grow significantly, driven by the increasing prevalence of hypertension and the adoption of combination therapies.
• North America and Europe are major markets, while the Asia-Pacific region is expected to show the strongest growth.
• Technological advancements, government initiatives, and favorable reimbursement policies are key drivers of the market.
• Generic formulations are becoming increasingly affordable, contributing to market growth.
• Potential side effects and regulatory scrutiny are among the challenges facing the market.

FAQs

What is the primary use of losartan-hydrochlorothiazide?

Losartan-hydrochlorothiazide is primarily used to treat high blood pressure (hypertension).

Which regions dominate the losartan-hydrochlorothiazide market?

North America and Europe currently dominate the market, while the Asia-Pacific region is expected to show the strongest growth.

What are the key drivers of the losartan-hydrochlorothiazide market?

The key drivers include the increasing prevalence of hypertension, growing adoption of combination therapies, technological advancements, and favorable government initiatives and reimbursement policies.

How much does losartan-hydrochlorothiazide typically cost?

The cost can vary, but for example, a supply of 30 tablets of 12.5 mg-50 mg hydrochlorothiazide/losartan can cost around $27.

What are the potential challenges facing the losartan-hydrochlorothiazide market?

Potential challenges include adverse effects, regulatory scrutiny, generic competition, and fluctuating raw material prices.

Sources

1. Cognitive Market Research: Global Losartan Market Report 2025.
2. Drugs.com: Hydrochlorothiazide/Losartan Prices, Coupons, Copay Cards & Patient Assistance.
3. Data Insights Market: Losartan Potassium Hydrochlorothiazide Tablet Market Overview.
4. OpenPR: Losartan Potassium Hydrochlorothiazide Tablet Market Will Generate Record Revenue by 2029.
5. Drugs.com: Losartan Prices, Coupons, Copay Cards & Patient Assistance.