Drug Price Trends for NEXTSTELLIS

Average Pharmacy Cost for NEXTSTELLIS

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
NEXTSTELLIS 3-14.2 MG TABLET	51862-0258-01	7.30543	EACH	2025-03-19
NEXTSTELLIS 3-14.2 MG TABLET	51862-0258-01	7.30655	EACH	2025-02-19
NEXTSTELLIS 3-14.2 MG TABLET	51862-0258-01	7.30689	EACH	2025-01-22
NEXTSTELLIS 3-14.2 MG TABLET	51862-0258-01	7.30388	EACH	2024-12-18

Market Analysis and Price Projections for NEXTSTELLIS

Introduction to NEXTSTELLIS

NEXTSTELLIS, a novel oral contraceptive, has been making significant waves in the contraceptive drugs market since its approval by the US FDA in April 2021. This drug combines 3 mg of drospirenone (DRSP) and 14.2 mg of estetrol (E4), a naturally occurring estrogen produced from a plant source, offering a unique mechanism of action compared to other contraceptives[3].

Market Size and Growth Projections

The global contraceptive drugs market, within which NEXTSTELLIS operates, is experiencing robust growth. As of 2023, the global market size was valued at USD 18.57 billion and is projected to reach USD 37.22 billion by 2032, exhibiting a CAGR of 8.2% during the forecast period of 2024-2032[4].

In the specific context of NEXTSTELLIS, its introduction has contributed to the market's expansion. The market is driven by increasing consumer awareness about birth control pills, supportive reimbursement policies, and the emergence of novel products like NEXTSTELLIS[2][4].

Regional Market Performance

North America, particularly the United States, is a significant market for NEXTSTELLIS. In 2023, the market size in North America was valued at USD 7.27 billion, with the U.S. segment expected to grow substantially, reaching an estimated value of USD 12.06 billion by 2032[4].

Key Drivers of Market Growth

Several factors are driving the growth of the contraceptive drugs market, including:

• Increasing Adoption of Modern Contraceptives: There is a shift from traditional to modern contraceptive methods, driven by rapid innovations and increased awareness about contraceptive techniques[2].
• Supportive Reimbursement Policies: Developed countries are implementing supportive reimbursement policies, making contraceptive drugs more accessible[2].
• Government Initiatives: Public programs aimed at creating awareness and growing insurance coverage are also boosting market growth[4].

Pricing and Affordability

NEXTSTELLIS is currently available as a brand-name drug only, with no generic version available. The cost for a 28-tablet supply of NEXTSTELLIS (3 mg-14.2 mg) is around $234, depending on the pharmacy. This price is for cash-paying customers and does not account for insurance plans[5].

To make NEXTSTELLIS more affordable, various discount programs and copay cards are available. For instance, the Drugs.com Discount Card can save consumers up to 80% or more off the cost of prescription medicines, including NEXTSTELLIS[5].

Clinical Trials and Efficacy

The efficacy and safety of NEXTSTELLIS were established through two open-label, single-arm trials: Study C301 (Europe/Russia) and Study C302 (North America). The primary endpoint was the Pearl Index, which measures the number of pregnancies occurring per 100 woman-years. The overall pregnancy rate for NEXTSTELLIS was 2.65 per 100 woman-years, with a trend of decreasing effectiveness observed with increasing BMI[1].

Market Challenges

While NEXTSTELLIS and the broader contraceptive drugs market are experiencing growth, there are challenges to consider:

• Side Effects: Contraceptive drugs, including NEXTSTELLIS, can have side effects, which may deter some users[3].
• Alternative Birth Control Methods: The increased usage of alternative birth control methods, such as IUDs and condoms, can also impact market growth[3].

Industry Developments

Recent industry developments highlight the expanding reach of NEXTSTELLIS. For example, in July 2022, Mithra Pharmaceuticals and Mayne Pharma Group Limited announced that NEXTSTELLIS is now available in Australia, further expanding its global presence[2].

Conclusion

NEXTSTELLIS is a significant player in the growing contraceptive drugs market. With its unique formulation and FDA approval, it has contributed to the market's expansion. The market is expected to continue growing, driven by increasing awareness, supportive policies, and the introduction of new products.

Key Takeaways

• Market Growth: The global contraceptive drugs market is projected to grow from USD 18.57 billion in 2023 to USD 37.22 billion by 2032.
• Regional Performance: North America, particularly the U.S., is a key market for NEXTSTELLIS.
• Pricing: NEXTSTELLIS is currently priced around $234 for a 28-tablet supply, with discount programs available.
• Efficacy and Safety: NEXTSTELLIS has been shown to be effective, with a Pearl Index of 2.65 per 100 woman-years.
• Challenges: Side effects and alternative birth control methods are potential challenges.

FAQs

What is NEXTSTELLIS and how does it differ from other contraceptives?

NEXTSTELLIS is an oral contraceptive that combines 3 mg of drospirenone (DRSP) and 14.2 mg of estetrol (E4), a naturally occurring estrogen produced from a plant source. It is the first and only contraceptive pill containing E4, offering a unique mechanism of action compared to other estrogens[3].

How effective is NEXTSTELLIS in preventing pregnancy?

NEXTSTELLIS has been shown to have an overall pregnancy rate of 2.65 per 100 woman-years, as evaluated by the Pearl Index. However, its effectiveness decreases with increasing BMI[1].

What are the key drivers of the contraceptive drugs market growth?

The market growth is driven by increasing adoption of modern contraceptive methods, supportive reimbursement policies, and government initiatives to boost awareness about contraceptive drugs[2][4].

Is NEXTSTELLIS available as a generic?

No, NEXTSTELLIS is currently available only as a brand-name drug, with no generic version available[5].

How much does NEXTSTELLIS cost?

The cost for a 28-tablet supply of NEXTSTELLIS is around $234, depending on the pharmacy. Discount programs and copay cards can help reduce the cost[5].

Sources

1. FDA: Drug Trials Snapshots: NEXTSTELLIS - FDA
2. GlobeNewswire: Contraceptive Drugs Market Size to Surpass USD 31.30 Billion by 2030
3. Mordor Intelligence: Contraceptive Pills Market Size & Share Analysis
4. Fortune Business Insights: Contraceptive Drugs Market Size, Share | Global Report, 2032
5. Drugs.com: Nextstellis Prices, Coupons, Copay Cards & Patient Assistance