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Last Updated: April 2, 2025

Drug Price Trends for PHYTONADIONE


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Drug Price Trends for PHYTONADIONE

Average Pharmacy Cost for PHYTONADIONE

These are average pharmacy acquisition costs (net of discounts) from a US national survey
Drug NameNDCPrice/Unit ($)UnitDate
PHYTONADIONE 5 MG TABLET 60687-0381-11 12.23410 EACH 2025-03-19
PHYTONADIONE 5 MG TABLET 16714-0973-02 12.23410 EACH 2025-03-19
PHYTONADIONE 5 MG TABLET 76282-0740-30 12.23410 EACH 2025-03-19
>Drug Name>NDC>Price/Unit ($)>Unit>Date
Showing 1 to 3 of 3 entries

Best Wholesale Price for PHYTONADIONE

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available to any customer under comparable terms and conditions
Drug NameVendorNDCCountPrice ($)Price/Unit ($)UnitDatesPrice Type
PHYTONADIONE 10MG/ML INJ Dr. Reddys Laboratories 43598-0405-16 25X1ML 746.00 2020-09-15 - 2025-09-14 FSS
PHYTONADIONE 1MG/0.5ML INJ SAF-T-JET SYR Amphastar Pharmaceuticals, Inc. 76329-1240-01 10X0.5ML 209.15 2022-01-15 - 2027-01-14 FSS
PHYTONADIONE 5MG TAB Exelan Pharmaceuticals, Inc. 76282-0740-30 30 204.51 6.81700 EACH 2024-02-13 - 2025-09-14 FSS
>Drug Name>Vendor>NDC>Count>Price ($)>Price/Unit ($)>Unit>Dates>Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies
Showing 1 to 3 of 3 entries

Market Analysis and Price Projections for Phytonadione

Market Size and Growth Projections

The vitamin K market, which includes phytonadione (Vitamin K1), is experiencing significant growth driven by several key factors. As of 2023, the global vitamin K market size was valued at USD 918.94 million, and it is projected to reach USD 2,126.08 million by 2033, growing at a Compound Annual Growth Rate (CAGR) of 8.75% from 2024 to 2033[1].

In the U.S., the vitamin K market size was USD 250.87 million in 2023 and is anticipated to grow to USD 580.42 million by 2033, also at a CAGR of 8.75%[1].

Drivers of Market Growth

The increasing prevalence of chronic disorders, such as coagulation disorders, diabetes, arthritis, and cardiovascular diseases, is a major driver of the vitamin K market. More than 71 million individuals aged 50 and over in the U.S. are affected by at least one chronic disease, and this number is expected to rise to over 142 million by 2050[4].

The adoption of unhealthy lifestyles and the consequent deficiency of vitamin K also contribute to the growing demand for phytonadione. The vitamin K1 segment, which includes phytonadione, is expected to grow at a CAGR of 8.2% from 2023 to 2032 due to its popularity in diet supplements and its role in treating blood clotting disorders[4].

Applications and Market Share

Phytonadione is widely used in various applications, including the treatment of hypoprothrombinemia, both induced by anticoagulants and not associated with anticoagulant therapy. It is also used as a prophylaxis for hypoprothrombinemia and in the treatment of hemorrhagic conditions in infants[2].

The osteoporosis application segment is another significant area, with the vitamin K market share from this segment exceeding USD 171 million in 2022. The growing burden of osteoporosis, affecting nearly 10 million people aged 50 years and above in the U.S., drives the demand for vitamin K supplements to improve bone density and reduce the risk of fractures[4].

Regional Market Analysis

North America is a key region for the vitamin K market, driven by the surging prevalence of chronic diseases and coagulation disorders. The region's market size is expected to reach over USD 858 million by 2032, fueled by unhealthy eating habits, increased healthcare expenditure, and a strong presence of pharmaceutical and nutraceutical industry players[4].

Price Projections and Trends

The prices of phytonadione vary based on the form and dosage. For example, the cost for phytonadione 5 mg oral tablets can range from $228.53 to $534.11 for a supply of 30 tablets, depending on the pharmacy and any available discounts[2].

For injectable solutions, the prices are as follows:

  • 1 mg/0.5 mL: Ranges from $70.70 to $261.75 for 5 milliliters.
  • 10 mg/mL: Ranges from $445.75 to $1,100.05 for 10 milliliters and 25 milliliters, respectively[2].

Company Performance and Sales

Companies like Amphastar Pharmaceuticals have seen significant growth in phytonadione sales. In 2022, Amphastar reported a 21% increase in phytonadione sales due to a combination of increased unit volumes and a higher average selling price[5].

Challenges and Limitations

Despite the growth, the vitamin K market faces challenges such as adverse effects associated with over-intake of vitamin K, including general body swelling, decreased appetite, upset stomach, and diarrhea. These side effects can limit the demand for phytonadione and other vitamin K supplements[4].

Key Takeaways

  • The global vitamin K market, including phytonadione, is projected to grow significantly, driven by the increasing prevalence of chronic disorders.
  • The U.S. market for vitamin K is expected to reach USD 580.42 million by 2033.
  • Phytonadione is used in various applications, including the treatment of hypoprothrombinemia and osteoporosis.
  • North America is a key region for the vitamin K market due to high healthcare expenditure and unhealthy lifestyles.
  • Prices of phytonadione vary based on form and dosage, with oral tablets and injectable solutions having different price ranges.
  • Companies are experiencing growth in phytonadione sales due to increased unit volumes and higher average selling prices.

FAQs

1. What is the projected growth rate of the global vitamin K market from 2024 to 2033? The global vitamin K market is projected to grow at a CAGR of 8.75% from 2024 to 2033[1].

2. What are the primary applications of phytonadione? Phytonadione is primarily used in the treatment of hypoprothrombinemia, both induced by anticoagulants and not associated with anticoagulant therapy, and in the treatment of hemorrhagic conditions in infants[2].

3. How much does a supply of phytonadione 5 mg oral tablets typically cost? The cost for phytonadione 5 mg oral tablets can range from $228.53 to $534.11 for a supply of 30 tablets, depending on the pharmacy and any available discounts[2].

4. What are the regional market trends for the vitamin K market? North America is a key region, driven by the surging prevalence of chronic diseases and coagulation disorders, with the market size expected to reach over USD 858 million by 2032[4].

5. What challenges does the vitamin K market face? The market faces challenges such as adverse effects associated with over-intake of vitamin K, including general body swelling, decreased appetite, upset stomach, and diarrhea[4].

Cited Sources:

  1. Precedence Research - Vitamin K Market Size, Share, and Trends 2024 to 2033
  2. Drugs.com - Phytonadione Prices, Coupons, Copay Cards & Patient Assistance
  3. FDA - ANDA 210189 - Phytonadione Tablets USP, 5 mg
  4. Global Market Insights - Vitamin K Market Projections | Industry Size Report, 2023-2032
  5. Amphastar Pharmaceuticals - News Detail - November 7, 2022

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