Drug Price Trends for TIAGABINE HCL

Average Pharmacy Cost for TIAGABINE HCL

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
TIAGABINE HCL 16 MG TABLET	72205-0087-30	6.25781	EACH	2025-03-19
TIAGABINE HCL 2 MG TABLET	00093-5030-56	2.17280	EACH	2025-03-19
TIAGABINE HCL 16 MG TABLET	00093-8076-56	6.25781	EACH	2025-03-19
TIAGABINE HCL 2 MG TABLET	62756-0200-83	2.17280	EACH	2025-03-19
TIAGABINE HCL 12 MG TABLET	00093-8072-56	5.30220	EACH	2025-03-19
TIAGABINE HCL 4 MG TABLET	72205-0085-30	2.05511	EACH	2025-03-19

Market Analysis and Price Projections for Tiagabine HCl

Introduction

Tiagabine HCl, marketed under the brand name Gabitril, is an antiepileptic drug that functions as a GABA uptake inhibitor. It is primarily used as adjunctive therapy for the treatment of partial seizures. Here, we will delve into the market analysis and price projections for Tiagabine HCl, covering its market size, key players, segmentation, and future outlook.

Market Size and Growth

The global Tiagabine HCl market has shown significant growth in recent years. As of 2023, the market was valued at several million USD, and it is anticipated to grow further, reaching a substantial value by 2030. This growth is expected to occur at a notable Compound Annual Growth Rate (CAGR)[4].

Key Players

The Tiagabine HCl market is dominated by several key players, including:

• Sun Pharmaceutical Industries
• Taj API
• Credit Chemwerth Pharmaceutical

These companies play a crucial role in the production, distribution, and innovation within the market[4].

Market Segmentation

The Tiagabine HCl market can be segmented based on several criteria:

By Type

The market is segmented into two main types based on purity:

• Above 98%
• Below 98%

This segmentation is critical for understanding the quality and application of the drug[4].

By Application

Tiagabine HCl is used in various forms, including:

• Tablets
• Capsules
• Other formulations

Each application has its own market share and growth prospects[4].

By Region

The market is also segmented geographically, with different regions contributing to the overall demand and supply. The regional analysis helps in understanding the market dynamics and potential growth areas[1].

Mechanism of Action and Clinical Use

Tiagabine HCl works by inhibiting the GAT-1 GABA transporter, thereby increasing the concentration of GABA in the synaptic cleft. This mechanism is crucial for its anticonvulsant properties. Clinical trials have shown that tiagabine HCl is effective in reducing the frequency of partial seizures when used as adjunctive therapy[3].

Clinical Studies and Efficacy

Several clinical studies have demonstrated the efficacy of tiagabine HCl in treating partial seizures. For example, in Study 1, patients receiving tiagabine HCl at doses of 32 mg/day and 56 mg/day showed a statistically significant reduction in seizure rates compared to the placebo group[3].

Price Projections

The pricing of Tiagabine HCl can vary based on several factors, including the dosage, form of the drug, and geographical location. Here are some key points regarding pricing:

Current Pricing

As of the current market, the average cost for 60 tablets of 4mg Tiagabine HCl is around $50.54 with a discount coupon, which is significantly lower than the retail price of $420.96[5].

Future Pricing Trends

Given the anticipated growth in the market, the prices of Tiagabine HCl may stabilize or decrease slightly due to increased competition and economies of scale. However, this will also depend on factors such as production costs, regulatory changes, and market demand.

Market Trends and Drivers

Several trends and drivers are influencing the Tiagabine HCl market:

Increasing Demand for Antiepileptic Drugs

The growing incidence of epilepsy and the need for effective treatment options are driving the demand for antiepileptic drugs like Tiagabine HCl.

Technological Advancements

Advancements in drug delivery systems and the development of new formulations are expected to enhance the market growth.

Regulatory Environment

Changes in regulatory policies and the approval of new drugs can significantly impact the market dynamics.

Challenges and Restraints

Despite the growth prospects, the Tiagabine HCl market faces several challenges:

Competition from Generic Drugs

The availability of generic versions of Tiagabine HCl can reduce the market share of branded products.

Side Effects and Contraindications

Tiagabine HCl has contraindications and potential side effects, which can affect its adoption rate.

Economic Factors

Economic fluctuations and changes in healthcare policies can impact the affordability and accessibility of the drug.

Regional Analysis

The global Tiagabine HCl market is diverse, with different regions contributing to its growth. Here is a brief overview of the regional market:

North America

This region is one of the largest markets for Tiagabine HCl due to the high prevalence of epilepsy and well-developed healthcare infrastructure.

Europe

Europe also represents a significant market, driven by the presence of major pharmaceutical companies and a strong regulatory framework.

Asia-Pacific

The Asia-Pacific region is expected to grow rapidly due to increasing healthcare expenditure and a large patient population.

Consumer Behavior Analysis

Consumer behavior plays a crucial role in the pharmaceutical market. Patients and healthcare providers are increasingly seeking effective and safe treatment options. The preference for branded versus generic drugs, adherence to treatment regimens, and the impact of patient education programs are key factors influencing the market[1].

Technological Trends

Technological advancements in the pharmaceutical industry are continuously shaping the market. For instance, improvements in drug formulation and delivery systems can enhance the efficacy and patient compliance of Tiagabine HCl.

"Tiagabine hydrochloride is a GABA uptake inhibitor (IC50 = 67 nM *in vivo*). Exhibits high affinity and selectivity for the GAT-1 GABA transporter. Anticonvulsant; also attenuates established dynorphin-induced allodynia in a mouse model after systemic administration."[2]

COVID-19 Impact

The COVID-19 pandemic has had a mixed impact on the pharmaceutical industry. While there were disruptions in supply chains and clinical trials, the demand for certain medications, including antiepileptic drugs, remained steady or even increased due to the heightened focus on healthcare.

Key Takeaways

• Market Growth: The Tiagabine HCl market is expected to grow at a significant CAGR from 2025 to 2031.
• Key Players: Sun Pharmaceutical Industries, Taj API, and Credit Chemwerth Pharmaceutical are the main players in the market.
• Segmentation: The market is segmented by type (above 98% and below 98% purity), application (tablets, capsules, etc.), and region.
• Clinical Use: Tiagabine HCl is effective as an adjunctive therapy for partial seizures.
• Pricing: Current prices are around $50.54 for 60 tablets of 4mg with a discount coupon, and future prices may stabilize or decrease slightly.
• Market Trends: Increasing demand for antiepileptic drugs, technological advancements, and regulatory changes are driving the market.

FAQs

What is the primary mechanism of action of Tiagabine HCl?

Tiagabine HCl works by inhibiting the GAT-1 GABA transporter, increasing the concentration of GABA in the synaptic cleft, which helps in reducing the frequency of seizures.

Which companies are the main players in the Tiagabine HCl market?

The main players in the Tiagabine HCl market include Sun Pharmaceutical Industries, Taj API, and Credit Chemwerth Pharmaceutical.

What are the common forms of Tiagabine HCl available in the market?

Tiagabine HCl is available in various forms, including tablets and capsules.

How does the COVID-19 pandemic impact the Tiagabine HCl market?

The COVID-19 pandemic has had a mixed impact, with some disruptions in supply chains but steady demand for antiepileptic drugs.

What is the expected growth rate of the Tiagabine HCl market from 2025 to 2031?

The market is expected to grow at a significant CAGR from 2025 to 2031, although the exact rate is not specified in the available data.

Sources

1. Global Tiagabine HCl Market Report 2024 Edition - Cognitivemarketresearch.com
2. Tiagabine hydrochloride - Tocris Bioscience
3. Tiagabine: Package Insert / Prescribing Information - Drugs.com
4. Global Tiagabine HCl Market Research Report 2024 - Valuates.com
5. Tiagabine (Gabitril): Uses, Side Effects, Dosage & Reviews - GoodRx