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Drug Price Trends for dantrolene sodium
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Average Pharmacy Cost for dantrolene sodium
| Drug Name | NDC | Price/Unit ($) | Unit | Date |
|---|---|---|---|---|
| DANTROLENE SODIUM 100 MG CAP | 64850-0842-01 | 0.95756 | EACH | 2025-03-19 |
| DANTROLENE SODIUM 25 MG CAP | 00115-4411-01 | 0.45243 | EACH | 2025-03-19 |
| DANTROLENE SODIUM 100 MG CAP | 49884-0364-01 | 0.95756 | EACH | 2025-03-19 |
| DANTROLENE SODIUM 25 MG CAP | 00904-7211-04 | 0.45243 | EACH | 2025-03-19 |
| DANTROLENE SODIUM 100 MG CAP | 00115-4433-01 | 0.95756 | EACH | 2025-03-19 |
| DANTROLENE SODIUM 50 MG CAP | 64850-0841-01 | 0.59662 | EACH | 2025-03-19 |
| >Drug Name | >NDC | >Price/Unit ($) | >Unit | >Date |
Dantrolene Sodium Market Analysis and Price Projections
Introduction to Dantrolene Sodium
Dantrolene sodium is a postsynaptic muscle relaxant that reduces excitation-contraction coupling in muscle cells, making it a critical medication for managing malignant hyperthermia, neuroleptic malignant syndrome, and certain types of muscle spasticity[1][3][4].
Market Size and Growth Projections
The global dantrolene sodium market has been experiencing significant growth. As of 2023, the market was valued at approximately $1.2 billion. It is anticipated to reach around $2.3 billion by 2030, with a Compound Annual Growth Rate (CAGR) of 8.4% during the forecast period of 2024-2030[1][3].
Regional Market Analysis
The dantrolene sodium market has a global footprint, with varying market sizes and growth rates across different regions.
- North America: This region, particularly the United States, is a leading market due to its well-established healthcare infrastructure and the presence of key market players[3].
- Europe: Countries like Germany, the UK, and France are significant contributors to the European market[3].
- Asia-Pacific: This region is expected to experience the fastest growth, driven by increasing awareness about malignant hyperthermia, expanding healthcare systems, and a growing burden of muscle-related disorders in countries like China, India, and Japan[3].
- Latin America and Middle East & Africa: These regions also present opportunities for growth, although the availability and accessibility of dantrolene sodium may be relatively lower compared to other regions[3].
Market Segmentation
The dantrolene sodium market is segmented based on several factors:
-
By Type: The market offers dantrolene sodium in various dosage forms, including oral capsules and injectable solutions[1][3].
- Dantrolene Sodium Capsules: Available in strengths such as 25 mg, 50 mg, and 100 mg[2].
- Dantrolene Sodium Injection: Used for emergency situations like malignant hyperthermia[2].
-
By Application: The primary applications include the treatment and prevention of malignant hyperthermia, treatment of neuroleptic malignant syndrome, and treatment of muscle spasms[1][3].
Competitive Landscape
The market is characterized by the presence of both established pharmaceutical companies and generic drug manufacturers. Key players include Livzon, Elite Pharma, Endo Pharm, Hikma, Eugia Pharma Specialities Limited, Eagle Pharmaceuticals, and others[1][4].
Price Analysis
The prices of dantrolene sodium vary based on the dosage form and quantity.
-
Oral Capsules:
- 25 mg capsules: Approximately $28 for a supply of 30 capsules[2].
- 50 mg capsules: Around $129 for a supply of 100 capsules[2].
- 100 mg capsules: About $138 for a supply of 100 capsules[2].
-
Intravenous Powder for Injection:
- 20 mg powder for injection: Starting from $81.83 per unit[2].
Driving Factors and Trends
Several factors are driving the growth of the dantrolene sodium market:
- Increasing Prevalence of Malignant Hyperthermia: The rising incidence of this life-threatening condition is a key driver[3].
- Growing Awareness and Recognition: Increased awareness about the importance of prompt treatment for malignant hyperthermia and the therapeutic benefits of dantrolene sodium are contributing to market growth[3].
- Research and Development: Ongoing efforts to explore new therapeutic applications and improve formulations are further driving the market[3][4].
- Geriatric Population: The increase in the geriatric population, which experiences more muscle stiffness and frequent muscle spasms, is another significant factor[4].
Challenges and Restraints
Despite the growth, the market faces several challenges:
- Side Effects: Adverse effects such as headache, nausea, drowsiness, and constipation associated with dantrolene sodium can hinder market growth[4].
- Low Incidence of Malignant Hyperthermia: Although the drug is critical, the relatively low incidence of malignant hyperthermia can limit market expansion[3].
- Regulatory Landscape: Evolving regulatory requirements can pose restraints to the market[3].
Cost-Effectiveness and Life-Saving Potential
Stocking dantrolene sodium, particularly in ambulatory surgical centers, has been shown to be highly cost-effective. According to a cost-effectiveness analysis, storing dantrolene could save 33 lives per year at an incremental cost-effectiveness ratio of nearly $200,000 per life saved[5].
"Storing dantrolene would save 33 lives per year at an incremental cost effectiveness ratio of nearly $200,000 (in 2010 dollars) per life saved, indicating that storing dantrolene at ambulatory surgical centers is very cost effective" - Malignant Hyperthermia Experts[5].
Future Projections and Opportunities
The dantrolene sodium market is poised for continued growth, driven by several factors:
- Technological Advancements: Integration of technological advancements, such as novel drug delivery systems, can enhance the convenience, safety, and efficacy of dantrolene sodium-based treatments[3].
- Emerging Markets: Regions like Asia-Pacific, Latin America, and the Middle East & Africa offer untapped potential as awareness about the availability and benefits of dantrolene sodium grows[3].
- New Therapeutic Applications: The exploration of potential new therapeutic applications, including the management of other muscle-related disorders or the prevention of heat-related illnesses, presents opportunities for market expansion[3].
Key Takeaways
- The global dantrolene sodium market is projected to grow significantly, reaching $2.3 billion by 2030.
- The market is driven by the increasing prevalence of malignant hyperthermia, growing awareness, and ongoing research and development.
- Key regions include North America, Europe, and the Asia-Pacific, with emerging markets offering further growth opportunities.
- The drug is available in various dosage forms, including oral capsules and injectable solutions.
- Despite challenges, the market is expected to benefit from technological advancements and the exploration of new therapeutic applications.
Frequently Asked Questions (FAQs)
What is the primary use of dantrolene sodium?
Dantrolene sodium is primarily used for the treatment and prevention of malignant hyperthermia, neuroleptic malignant syndrome, and certain types of muscle spasticity[1][3][4].
What are the different dosage forms of dantrolene sodium?
Dantrolene sodium is available in oral capsules (25 mg, 50 mg, 100 mg) and injectable solutions[2].
What is the projected market size of dantrolene sodium by 2030?
The global dantrolene sodium market is expected to reach around $2.3 billion by 2030[1][3].
Which regions are leading the dantrolene sodium market?
North America, particularly the United States, and Europe are leading markets, with the Asia-Pacific region expected to experience the fastest growth[3].
What are the key challenges facing the dantrolene sodium market?
The market faces challenges such as side effects, the low incidence of malignant hyperthermia, and evolving regulatory requirements[3][4].
How cost-effective is stocking dantrolene sodium?
Stocking dantrolene sodium, especially in ambulatory surgical centers, is highly cost-effective, saving lives at an incremental cost-effectiveness ratio of nearly $200,000 per life saved[5].
Cited Sources
- Global Dantrolene Sodium Market Research Report 2024 - QY Research[1]
- Dantrolene Prices, Coupons, Copay Cards & Patient Assistance - Drugs.com[2]
- Dantrolene Sodium Market Size, Share, Growth, Statistics Report 2033 - Data Horizon Research[3]
- Dantrolene Sodium Market Size, Share and Forecast 2030 - Allied Market Research[4]
- Experts Say Stocking the Drug Dantrolene Saves Lives and Money - Malignant Hyperthermia Association of the United States[5]
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