Drug Price Trends for tirosint

Average Pharmacy Cost for tirosint

These are average pharmacy acquisition costs (net of discounts) from a US national survey

Drug Name	NDC	Price/Unit ($)	Unit	Date
TIROSINT 44 MCG CAPSULE	71858-0013-04	4.52634	EACH	2024-07-17
TIROSINT 13 MCG CAPSULE	71858-0005-04	4.49998	EACH	2024-07-01
TIROSINT-SOL 88 MCG/ML SOLN	71858-0125-05	4.51145	ML	2024-07-01
TIROSINT 100 MCG CAPSULE	71858-0030-04	4.49375	EACH	2024-07-01

Tirosint Market Analysis and Financial Projection

Market Analysis and Price Projections for Tirosint (Levothyroxine)

Introduction to Tirosint

Tirosint, a brand-name medication, is a liquid form of levothyroxine sodium, used to treat hypothyroidism and for TSH suppression in the management of certain thyroid cancers. It was approved by the FDA in 2017 for the American market, marking a significant innovation in thyroid hormone replacement therapy[1].

Market Overview

Prevalence of Thyroid Disorders

Thyroid disorders, including hypothyroidism, are increasingly common, affecting a substantial portion of the global population. In the United States alone, it is estimated that around 12% of the population will suffer from thyroid disorders at some point in their lives, with approximately 20 million Americans currently affected[4].

Market Size and Growth

The global levothyroxine market, which includes Tirosint, was valued at $3.8 billion in 2023 and is projected to grow at a CAGR of 3.3% from 2024 to 2034, reaching $5.4 billion by the end of the forecast period. This growth is driven by the rising prevalence of thyroid disorders and advancements in healthcare infrastructure[4].

Regional Market Analysis

• North America: This region is dominant in the levothyroxine market, driven by a sophisticated healthcare system and high diagnostic capabilities. The U.S. market, in particular, is expected to exhibit a CAGR of 4.2% during the forecast period[3][4].
• Europe: Europe also holds a significant share, particularly due to the higher prevalence of thyroid disorders among the elderly population.
• Asia Pacific: This region is growing rapidly, with China being a key market, driven by increasing healthcare spending and a large patient population[4].

Key Indications and Patient Population

Hypothyroidism

Hypothyroidism is the primary indication for Tirosint, affecting an estimated 6% of the U.S. population. The condition is often caused by chronic autoimmune thyroiditis and, if untreated, can lead to significant health complications such as cardiovascular risk, infertility, and pregnancy complications[1].

Thyroid Cancer

Tirosint is also used for TSH suppression in the management of certain thyroid cancers. The precise dosing and consistent absorption of Tirosint make it an effective option for these patients[1].

Clinical Advantages of Tirosint

Overcoming Limitations of Traditional Tablets

Tirosint-SOL, the liquid form of levothyroxine, has been shown to overcome some limitations of traditional levothyroxine tablets. Clinical studies in Italy have demonstrated that the liquid form does not require the hour-long wait before eating breakfast and is less affected by medications like antacids or proton pump inhibitors. This makes it particularly beneficial for patients who cannot swallow tablets or are fed through tubes[1].

Patient Compliance and Ease of Use

The liquid formulation of Tirosint enhances patient compliance, especially for children and patients with swallowing difficulties. It also allows for more precise dosing, which is crucial for maintaining optimal thyroid hormone levels[1].

Pricing and Cost Analysis

Retail Prices

The cost of Tirosint varies depending on the dosage and pharmacy. For example, a 30-day supply of Tirosint oral capsules can range from $159 to $170, depending on the pharmacy and the specific dosage[5].

Generic Alternatives

A generic version of levothyroxine is available, which can be significantly cheaper, with prices starting from $135.67 for a 30-day supply[5].

Patient Assistance Programs

Patients can benefit from various discount cards, coupons, and copay cards that can reduce the cost of Tirosint. These programs are designed to make the medication more affordable for those without adequate insurance coverage[5].

Market Projections and Trends

Growing Demand

The demand for thyroid medications, including Tirosint, is expected to rise due to the increasing prevalence of thyroid disorders. The global injectable thyroid drug market, which includes levothyroxine, is projected to grow at a CAGR of 5.7% from 2024 to 2034, reaching $765.4 million by the end of the forecast period[3].

Competitive Landscape

The levothyroxine market is highly competitive, with key players such as AbbVie, Mylan N.V., Merck & Co., Inc., Pfizer Inc., and others. These companies are focusing on upgrading their product portfolios, collaborating on research, and expanding their distribution channels to maintain market share[4].

Distribution Channels

Hospital pharmacies currently hold the largest share in the levothyroxine market, followed by retail pharmacies and online pharmacies. The market attractiveness analysis suggests that hospital pharmacies will continue to dominate due to their direct access to patients and comprehensive healthcare services[4].

Key Takeaways

• Market Growth: The levothyroxine market, including Tirosint, is expected to grow significantly due to the rising prevalence of thyroid disorders.
• Clinical Advantages: Tirosint-SOL offers several clinical advantages over traditional tablets, including better absorption and ease of use.
• Pricing: While Tirosint can be expensive, generic alternatives and patient assistance programs can make it more affordable.
• Regional Markets: North America, particularly the U.S., is a key market for Tirosint, followed by Europe and Asia Pacific.
• Competitive Landscape: The market is highly competitive, with major pharmaceutical companies focusing on product innovation and distribution expansion.

FAQs

What is Tirosint used for?

Tirosint is used to treat hypothyroidism and for TSH suppression in the management of certain thyroid cancers.

What are the advantages of Tirosint over traditional levothyroxine tablets?

Tirosint-SOL, the liquid form of levothyroxine, does not require waiting an hour before eating breakfast and is less affected by medications like antacids or proton pump inhibitors.

How much does Tirosint cost?

The cost of Tirosint can range from $159 to $170 for a 30-day supply, depending on the pharmacy and dosage. Generic alternatives are available at a lower cost.

What patient populations benefit most from Tirosint?

Patients who cannot swallow tablets, children with hypothyroidism, and those fed through tubes benefit significantly from the liquid formulation of Tirosint.

What is the projected market growth for levothyroxine medications like Tirosint?

The global levothyroxine market is expected to grow at a CAGR of 3.3% from 2024 to 2034, reaching $5.4 billion by the end of the forecast period.

Sources

1. The FDA Has Approved Tirosint-SOL, Levothyroxine In Liquid Solution For The American Market, IBSA Patent. Biospace, February 15, 2017.
2. Tirosint Coupons & Prices. SingleCare.
3. Injectable Thyroid Drug Market Share, Trend & Forecast 2034. Future Market Insights.
4. Levothyroxine Market Size, Share, Analysis to 2034. Transparency Market Research.
5. Tirosint Prices, Coupons, Copay Cards & Patient Assistance. Drugs.com.