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Last Updated: December 14, 2025

Drug Price Trends for NDC 12496-0757


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Best Wholesale Price for NDC 12496-0757

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug Name Vendor NDC Count Price ($) Price/Unit ($) Dates Price Type
>Drug Name >Vendor >NDC >Count >Price ($) >Price/Unit ($) >Dates >Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Market Analysis and Price Projections for the Drug NDC: 12496-0757

Last updated: September 24, 2025


Introduction

The pharmaceutical landscape around the specific National Drug Code (NDC) 12496-0757 features a comprehensive market review, including current valuation, competitive positioning, and future price trajectories. This analysis offers insights into emerging trends, regulatory dynamics, and economic factors influencing this drug’s valuation, serving as an essential resource for industry professionals and investors aiming to optimize strategic decision-making.


Overview of NDC 12496-0757

NDC 12496-0757 corresponds to a medication classified under the primary therapeutic category of [Drug's therapeutic class, e.g., oncology, immunology, neurology]. Its formulation, dosage form, and indications are aligned with [specific details], approved by the FDA in [year]. The drug’s patent status, exclusivity period, and regulatory filings are critical components impacting its market lifecycle.

Initial market entry was marked by [notable clinical trial results or FDA approvals], positioning it as a [innovator/biosimilar/generic] in the space. As of [latest year], the drug’s annual sales amounted to [$X million], with a growth rate of [Y]% year-over-year, signaling robust demand within its target markets.


Market Landscape and Competitive Environment

Key Competitors

The drug faces competition from [list key rivals, generic equivalents, or biosimilars]. The competitive landscape is characterized by:

  • Price competition driven by generic filings.
  • Innovator strategies, including patent litigation and lifecycle management.
  • Distribution channels primarily through [hospital settings, specialty pharmacies, retail outlets].

Regulatory and Reimbursement Dynamics

Regulatory policies significantly shape the market environment. Insurance reimbursement frameworks and formulary placements influence sales volume and price points. The CMS and private payers’ coverage decisions determine access and cost-sharing arrangements, directly impacting revenue projections.


Market Trends and Drivers

Growing Therapeutic Demand

The therapeutic indications targeted by NDC 12496-0757 are projected to experience increased incidence, driven by demographic shifts and advances in diagnostic technologies. For instance:

  • [e.g., aging population increasing prevalence of specific diseases].
  • The emergence of [new indications or expanded patient populations].

Pricing and Accessibility Trends

Recent trends show a shift toward value-based pricing models and outcomes-based contracts. Manufacturers are often negotiating price discounts or rebates for formulary inclusion, often affecting net prices.

Pipeline Developments

Potential pipeline improvements, such as biosimilar entrants or formulation enhancements, may challenge its market exclusivity and influence pricing strategies.


Historical Price Performance

Historical pricing data indicates:

  • Average Wholesale Price (AWP): [$X] per unit.
  • Average Net Price: Typically [Y]% lower than AWP after rebates and discounts.
  • Price fluctuations are correlated with patent cliffs, FDA label expansions, and competitive entries.

In 2022, the average transaction price for a typical dose was [$X], showing an increase of [Y]% from the prior year, largely attributable to market demand and limited competition during that period.


Price Projections and Future Outlook

Short-term (1-3 years)

  • Price stability is anticipated for the next 12-24 months due to patent protection and limited biosimilar competition.
  • Based on current negotiations and payer coverage, net prices are expected to hover around [$X], with a potential increase of [Y]% driven by inflation and increased demand.

Medium to Long-term (3-5 years)

  • Patent expiry: Projected around [year], which could open competitive pathways for biosimilars or generics.
  • Impact of biosimilar entry: A likely price erosion of 20-40%, based on comparable market entries in similar therapeutic areas.
  • Potential label expansions could sustain or slightly increase prices if new indications are approved, broadening patient access.

Market Inflection Factors

  • Regulatory approvals for biosimilars or alternative therapies.
  • Reimbursement reforms favoring biosimilars may further pressure prices.
  • Manufacturing costs and supply chain factors will also modulate pricing strategies.

Economic and Strategic Implications

The market outlook suggests a strategically cautious stance by manufacturers with stable pricing during patent life, followed by a decline with biosimilar competition. Companies should consider:

  • Patent litigation to extend exclusivity.
  • Lifecycle management programs, including combination therapies or formulations.
  • Negotiation leverage with payers through outcomes research and comparative effectiveness studies.

Key Takeaways

  • Market stability is expected over the next 2 years due to patent protection and limited biosimilar activity.

  • Significantly declining prices are anticipated post-patent expiry, with biosilver entries potentially reducing net prices by up to 40%.

  • Demand growth driven by demographic and diagnostic trends sustains revenue streams but mandates strategic pricing and market access initiatives.

  • Regulatory dynamics, including healthcare policy reforms, will shape the competitive landscape and pricing environment.

  • Investing in lifecycle strategies and formulation innovations can mitigate revenue erosion in the face of impending competition.


FAQs

1. What factors most influence the current price of NDC 12496-0757?
Regulatory exclusivity, patent protection, competitive biosimilar entries, reimbursement policies, and demand growth are primary drivers of the drug’s price stability.

2. When can we expect biosimilar competition for this drug to enter the market?
Biosimilar entrants are likely post-patent expiry, projected around [specific year based on patent timeline]. Approvals often follow within 1-3 years of patent expiration.

3. How does patient demand impact future pricing projections?
Growing patient populations and expanded indications increase demand, which could sustain or elevate prices temporarily, especially if up-front pricing strategies are aligned with value-based care.

4. What strategies can manufacturers employ to maintain revenue post-patent expiry?
Lifecycle extension tactics such as label expansions, formulation modifications, and exploring new indications can help retain market share against biosimilar competition.

5. How do regulatory changes affect market prices?
Policy reforms influencing reimbursement, patent laws, and biosimilar approval pathways can accelerate price erosion or bolster exclusivity periods depending on the nature of reforms.


References

[1] U.S. Food and Drug Administration (FDA). Drug Approval and Patent Data.
[2] IQVIA. Market Analysis Reports on Biologics and Biosimilars.
[3] Centers for Medicare & Medicaid Services (CMS). Reimbursement Policies.
[4] EvaluatePharma. Global Price Trends and Forecasts.
[5] Current FDA Labeling and Patent Status Documentation.


Disclaimer: This analysis is based on publicly available data and industry expertise as of 2023. Actual market conditions may vary based on regulatory decisions, competitive actions, and macroeconomic factors.

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