Drug Price Trends for NDC 00009-0746

Average Pharmacy Cost for 00009-0746

Drug Name	NDC	Price/Unit ($)	Unit	Date
DEPO-PROVERA 150 MG/ML VIAL	00009-0746-30	50.54200	ML	2025-04-23
DEPO-PROVERA 150 MG/ML VIAL	00009-0746-30	50.54200	ML	2025-03-19
DEPO-PROVERA 150 MG/ML VIAL	00009-0746-30	50.54200	ML	2025-02-19
DEPO-PROVERA 150 MG/ML VIAL	00009-0746-30	50.54200	ML	2025-01-22

Best Wholesale Price for NDC 00009-0746

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
No data available in table

Market Analysis and Price Projections for Depo-Provera (NDC: 00009-0746)

Depo-Provera, a popular injectable contraceptive, has been a staple in the pharmaceutical market for decades. As we look towards 2025 and beyond, it's crucial to understand the market dynamics and price projections for this widely used drug. Let's dive into a comprehensive analysis of Depo-Provera, focusing on its market position, pricing trends, and future outlook.

Understanding Depo-Provera

Depo-Provera, with the National Drug Code (NDC) 00009-0746, is a contraceptive injection containing medroxyprogesterone acetate. It's primarily used for birth control, but also has applications in treating certain types of cancer and endometriosis[1].

How Depo-Provera Works

The drug works by inhibiting the secretion of gonadotropins, which primarily prevents follicular maturation and ovulation[1]. This mechanism of action makes it an effective long-term contraceptive option for many women.

Available Formulations

Depo-Provera is available in various formulations, including:

• 150 mg/mL single-dose vials (NDC 0009-0746-30)
• 150 mg/mL prefilled syringes (NDC 0009-0746-35)
• 104 mg/0.65 mL prefilled syringes (NDC 0009-7376-11)[1]

Current Market Position

As of 2023, Depo-Provera remains a significant player in the contraceptive market. Its long-acting nature and effectiveness have contributed to its continued popularity among healthcare providers and patients.

Market Share and Sales

While specific sales figures for Depo-Provera are not provided in the search results, we can infer its importance from broader market data. In 2023, the top 10 drugs selected for negotiation under the Medicare Drug Price Negotiation Program accounted for $56.2 billion in total Part D gross covered prescription drug costs, representing about 20% of total Part D gross covered prescription drug costs[2].

User Base

The drug's user base is substantial, with millions of women worldwide relying on Depo-Provera for contraception. In the United States alone, about 9 million Medicare enrollees used the top 10 negotiated drugs in 2023[2], indicating the significant market presence of widely used medications like Depo-Provera.

Pricing Trends and Projections

Understanding the pricing trends for Depo-Provera is crucial for both healthcare providers and patients. Let's examine the current pricing landscape and projections for the future.

Historical Price Changes

While specific historical price data for Depo-Provera is not provided in the search results, we can look at general trends in the pharmaceutical industry. Between 2018 and 2023, nine out of ten drugs selected for the first year of Medicare price negotiation saw list price increases ranging from 20% to 55%[2].

Nine of the 10 drugs selected for the first cycle of negotiation had list price increases between 2018 and 2023; the list price increases ranged from a low of 20% for Farxiga to a high of 55% Enbrel.[2]

Projected Price Changes

Looking ahead to 2025 and beyond, several factors are likely to influence the pricing of Depo-Provera:

1. Medicare Drug Price Negotiation Program: This program, set to begin in 2026, could significantly impact drug prices, including potentially Depo-Provera[2].

2. Overall market trends: Experts predict continued moderate growth of 4-6% in overall drug expenditures across the entire U.S. market[4].

3. Sector-specific growth: The clinic sector is expected to experience high (11-13%) growth in drug spending in 2019, which could extend to future years[4].

Factors Influencing Future Pricing

Several key factors are likely to shape the pricing of Depo-Provera and similar drugs in the coming years.

Policy and Regulatory Changes

The pharmaceutical industry is bracing for potential policy changes that could significantly impact drug pricing:

1. Medicare Drug Price Negotiation Program: Set to begin in 2026, this program aims to make prescription drugs more affordable for Medicare enrollees and taxpayers[2].

2. New administration policies: The incoming administration's health policies, tariffs, taxes, and M&A oversight could accelerate changes in the pharmaceutical market[3].

Market Dynamics

Shifting market dynamics are also likely to influence Depo-Provera's pricing:

1. Value creation trends: The health ecosystem is moving towards prevention, personalization, prediction, and point of care[3].

2. Portfolio diversification: Pharmaceutical companies are evolving their portfolios based on scientific and technological breakthroughs[7].

3. Supply chain optimization: Companies are focusing on building resilience and sustainability in their supply chains[7].

Technological Advancements and R&D

Technological advancements, particularly in AI and data analytics, are set to play a crucial role in shaping the future of pharmaceutical pricing and development.

AI in Drug Development

Pharmaceutical companies are heavily investing in AI to foster innovation and reduce drug development costs:

• 85% of biopharma executives plan to invest in data, digital, and AI in R&D for 2025[7].
• One top-10 pharma company expects to save roughly $1 billion in drug development costs over five years[7].

Patient-Centric Trials

The industry is moving towards more patient-centric clinical trials, which could impact drug development costs and, ultimately, pricing:

• Amgen has doubled its clinical trial enrollment speed using a multimodal, data-driven machine learning tool[7].
• Sanofi is collaborating with OpenAI and Formation Bio to develop an AI tool that reduces patient recruitment timelines "from months to minutes"[7].

Competition and Market Alternatives

The competitive landscape for contraceptives is evolving, which could impact Depo-Provera's market position and pricing.

Emerging Contraceptive Options

New contraceptive options entering the market could provide alternatives to Depo-Provera, potentially influencing its pricing:

• Novel modalities and mechanisms of action (MOAs) are being developed across the pharmaceutical industry[7].
• Companies are focusing on therapy areas with high unmet needs, which could include new contraceptive options[7].

Generic Competition

While specific information about generic competition for Depo-Provera is not provided in the search results, the potential for generic alternatives could significantly impact pricing in the future.

Global Market Considerations

The global nature of the pharmaceutical market means that international trends and considerations will play a role in Depo-Provera's pricing.

Emerging Markets

Pharmaceutical companies are increasingly focusing on emerging markets:

• Companies are growing their footprint in emerging markets primed for growth[7].
• This expansion could lead to increased production and potentially impact global pricing strategies.

International Price Comparisons

International price comparisons are becoming increasingly important in discussions about drug pricing:

• The MIDAS data contains estimates of prescription drug sales and volume based on audits of prescription drug transactions in various countries[8].
• These comparisons could influence domestic pricing strategies and regulatory decisions.

Supply Chain Considerations

The pharmaceutical supply chain is undergoing significant changes, which could impact the production and distribution costs of drugs like Depo-Provera.

Domestic Manufacturing

There's a growing focus on domestic manufacturing in the pharmaceutical industry:

• Companies are strengthening their domestic manufacturing capabilities to address political changes and ensure supply continuity[7].
• This shift could impact production costs and, consequently, drug pricing.

Smart Manufacturing

The adoption of smart manufacturing techniques is on the rise:

• 90% of biopharma executives are investing in smart manufacturing to increase supply chain efficiency[7].
• Companies like Amgen and Roche are leading examples of this trend[7].

Patient Access and Affordability

As discussions around drug pricing continue, patient access and affordability remain key considerations.

Insurance Coverage

The extent of insurance coverage for Depo-Provera will play a crucial role in patient access:

• Medicare Part D coverage decisions could significantly impact patient out-of-pocket costs[2].
• Private insurance coverage trends will also influence overall affordability.

Patient Assistance Programs

Pharmaceutical companies often offer patient assistance programs to improve access to their medications. The future of these programs for Depo-Provera could impact its overall affordability and market position.

Future Market Outlook

As we look towards 2025 and beyond, several trends are likely to shape the market for Depo-Provera and similar drugs.

Personalized Medicine

The trend towards personalized medicine could impact the contraceptive market:

• Data-driven, customized treatments based on factors like genetics and behavior are becoming more common[3].
• This could lead to more tailored contraceptive options, potentially influencing Depo-Provera's market position.

Sustainable Practices

Sustainability is becoming increasingly important in the pharmaceutical industry:

• Companies are optimizing their supply chains for sustainability and resilience[7].
• This focus on sustainability could impact production methods and costs.

Key Takeaways

1. Depo-Provera remains a significant player in the contraceptive market, with a substantial user base.
2. Future pricing will be influenced by factors such as the Medicare Drug Price Negotiation Program, overall market trends, and sector-specific growth.
3. Technological advancements, particularly in AI and data analytics, are set to play a crucial role in drug development and pricing.
4. The competitive landscape is evolving, with new contraceptive options potentially entering the market.
5. Global market considerations, including expansion into emerging markets, will impact pricing strategies.
6. Supply chain optimization and a focus on domestic manufacturing could influence production costs.
7. Patient access and affordability remain key considerations in the ongoing drug pricing discussion.
8. The trend towards personalized medicine and sustainable practices will shape the future market for contraceptives like Depo-Provera.

FAQs

1. Q: How might the Medicare Drug Price Negotiation Program affect Depo-Provera's pricing? A: While specific impacts are yet to be seen, the program aims to make prescription drugs more affordable for Medicare enrollees and taxpayers, which could lead to price reductions for drugs like Depo-Provera.

2. Q: What role will AI play in the future of contraceptive development and pricing? A: AI is expected to significantly reduce drug development costs and timelines, potentially leading to more efficient production and competitive pricing for contraceptives.

3. Q: How might emerging markets influence Depo-Provera's global pricing strategy? A: As pharmaceutical companies expand into emerging markets, they may adjust their global pricing strategies to accommodate different economic conditions, potentially impacting Depo-Provera's pricing worldwide.

4. Q: What impact could personalized medicine have on the contraceptive market? A: The trend towards personalized medicine could lead to more tailored contraceptive options, potentially influencing Depo-Provera's market position and pricing.

5. Q: How might sustainability initiatives in the pharmaceutical industry affect Depo-Provera's production and pricing? A: A focus on sustainable practices could lead to changes in production methods and supply chain management, potentially impacting the overall cost structure and pricing of drugs like Depo-Provera.

Sources cited: [1] https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=199cf13e-0859-4a73-9b45-e700d0cd1049 [2] https://aspe.hhs.gov/sites/default/files/documents/3e8abec86039ac0ed674a8c5fac492e3/price-change-over-time-brief.pdf [3] https://www.pwc.com/us/en/industries/pharma-life-sciences/pharmaceutical-industry-trends.html [4] https://pubmed.ncbi.nlm.nih.gov/31199861/ [7] https://www.zs.com/insights/pharmaceutical-trends-2025-outlook-ai-supplychain-and-beyond [8] https://aspe.hhs.gov/sites/default/files/documents/bc582e25376d714694524a492fb15f36/international-prescription-drug-price-comparisons.pdf