Drug Price Trends for NDC 42794-0007

Average Pharmacy Cost for 42794-0007

Drug Name	NDC	Price/Unit ($)	Unit	Date
PROTRIPTYLINE HCL 10 MG TABLET	42794-0007-02	2.40979	EACH	2025-04-23
PROTRIPTYLINE HCL 10 MG TABLET	42794-0007-02	2.41685	EACH	2025-03-19
PROTRIPTYLINE HCL 10 MG TABLET	42794-0007-02	2.45565	EACH	2025-02-19
PROTRIPTYLINE HCL 10 MG TABLET	42794-0007-02	2.43507	EACH	2025-01-22

Best Wholesale Price for NDC 42794-0007

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions

Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies

Drug Name	Vendor	NDC	Count	Price ($)	Price/Unit ($)	Dates	Price Type
No data available in table

Market Analysis and Price Projections for Liothyronine Sodium (NDC: 42794-018)

Introduction

Liothyronine sodium, a synthetic form of the thyroid hormone triiodothyronine (T3), is used to treat hypothyroidism and other thyroid disorders. Here, we will delve into the market analysis and price projections for this drug, using the NDC 42794-018 as a reference.

Market Overview

The thyroid hormone replacement market, which includes liothyronine sodium, is a segment of the broader endocrine disorder treatment market. This market is characterized by a mix of branded and generic products, with the latter playing a significant role due to patent expirations and generic approvals.

Current Market Status

• Generic Competition: Liothyronine sodium is available as a generic drug, which has been marketed since 2012 by various manufacturers, including SigmaPharm Laboratories, LLC[1].
• Market Size: The overall thyroid hormone replacement market is substantial, but specific data on liothyronine sodium's market share is less detailed. However, it is part of a larger market that includes both T3 and T4 (levothyroxine) therapies.

Price Trends

• General Trends: Prescription drug prices, including those for generic drugs like liothyronine sodium, have seen significant increases over the years. According to a report by the Assistant Secretary for Planning and Evaluation (ASPE), most price increases occur in January and July, with January 2022 seeing an average price increase of nearly $150 per drug (10%)[2].
• Specific to Liothyronine Sodium: While specific price data for NDC 42794-018 is not provided in the sources, generic drugs have generally seen price fluctuations. For instance, the median price increase for generic drugs in 2022 was 19.9% in Oregon's Drug Price Transparency Program[5].

Factors Influencing Price

• Inflation and Economic Conditions: The Consumer Price Index (CPI) affects drug prices. For example, the CPI increased by 8.5% between July 2021 and July 2022, which can influence drug price adjustments[2].
• Regulatory Environment: Transparency programs and regulatory oversight can impact pricing strategies. For instance, Oregon's Drug Price Transparency Program requires detailed reporting on price increases, which can influence manufacturer decisions[5].
• Market Competition: The presence of multiple generic manufacturers can lead to competitive pricing. However, significant price increases can still occur, as seen with some generic drugs experiencing increases of over 500% in certain cases[2].

Price Projections

• Short-Term Projections: Given the historical trend of price increases in January and July, it is likely that liothyronine sodium will see price adjustments in these periods. The average price increase in January 2022 was around 10%, which could be a benchmark for future increases[2].
• Long-Term Projections: The overall market for thyroid hormone replacement is stable, but generic competition and regulatory pressures may keep price increases in check. However, the lack of specific data on liothyronine sodium's pricing history makes precise long-term projections challenging.

Impact of Generic Competition

• Patent Expirations: The availability of generic liothyronine sodium since 2012 has reduced the market share of branded versions. This trend is expected to continue, with generic sales potentially stabilizing or slightly increasing due to their cost-effectiveness[3].
• Market Share: Generic drugs, including liothyronine sodium, are likely to maintain a significant market share due to their lower cost compared to branded alternatives.

Physician and Patient Perspectives

• Treatment Preferences: Physicians often prefer branded drugs for their perceived quality and efficacy, but cost considerations and patient affordability can drive the use of generics. Patient compliance and treatment outcomes are crucial factors in choosing between branded and generic options[3].

Key Takeaways

• Price Volatility: Liothyronine sodium, like other generic drugs, is subject to price increases, particularly in January and July.
• Generic Competition: The presence of multiple generic manufacturers helps in keeping prices relatively stable but can still see significant increases.
• Regulatory Influence: Transparency programs and regulatory oversight play a crucial role in shaping pricing strategies.
• Market Stability: The thyroid hormone replacement market is stable, but prices can fluctuate based on economic and regulatory factors.

FAQs

1. What is the current market status of liothyronine sodium?

   • Liothyronine sodium is available as a generic drug and has been marketed since 2012 by various manufacturers.

2. When are the most significant price increases for prescription drugs, including liothyronine sodium, likely to occur?

   • The most significant price increases typically occur in January and July each year.

3. How does inflation affect the pricing of liothyronine sodium?

   • Inflation, as measured by the Consumer Price Index (CPI), can influence drug price adjustments, with prices often increasing in line with or slightly above the rate of inflation.

4. What role does generic competition play in the pricing of liothyronine sodium?

   • Generic competition helps keep prices relatively stable but can still result in significant price increases due to various market and regulatory factors.

5. How do regulatory transparency programs impact the pricing of liothyronine sodium?

   • Regulatory transparency programs, such as Oregon's Drug Price Transparency Program, require detailed reporting on price increases, which can influence manufacturer pricing strategies and provide accountability.

Sources

1. FDA.report - NDC 42794-018 Oral Tablet Liothyronine Sodium Drug
2. ASPE - Price Increases for Prescription Drugs, 2016-2022
3. GlobalData - NSCLC MARKET - Global Drug Forecast & Market Analysis to 2025
4. FDA - National Drug Code Directory
5. Oregon's Drug Price Transparency Program - Prescription Drug Price Transparency Results and Recommendations