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Last Updated: April 27, 2025

Drug Price Trends for NDC 52427-0272


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Best Wholesale Price for NDC 52427-0272

These are wholesale prices available to the US Federal Government which, by law, must be the best prices available under comparable terms and conditions
Drug NameVendorNDCCountPrice ($)Price/Unit ($)DatesPrice Type
NAPRELAN ORAL EXTENDED RELEASE 375MG TAB TWi Pharmaceuticals USA, Inc. 52427-0272-01 100 1610.24 16.10240 2024-01-01 - 2028-01-31 FSS
NAPRELAN ORAL EXTENDED RELEASE 375MG TAB TWi Pharmaceuticals USA, Inc. 52427-0272-01 100 1467.82 14.67820 2023-11-01 - 2028-01-31 FSS
>Drug Name>Vendor>NDC>Count>Price ($)>Price/Unit ($)>Dates>Price Type
Price type key: Federal Supply Schedule (FSS): generally available to all Federal Govt agencies / 'BIG4' prices: VA, DoD, Public Health & Coast Guard only / National Contracts (NC): Available to specific agencies
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Market Analysis and Price Projections for the Drug NDC: 52427-285 (Macrobid)

Introduction

The pharmaceutical market is dynamic and influenced by various factors, including technological advancements, regulatory changes, and economic trends. This article focuses on the market analysis and price projections for Macrobid, a drug identified by the National Drug Code (NDC) 52427-285.

Drug Overview

Macrobid, with the NDC 52427-285, is a human prescription drug containing Nitrofurantoin Monohydrate/Macrocrystalline. It is marketed by Almatica Pharma Inc. and is used primarily for the treatment of urinary tract infections[1].

Market Trends in Pharmaceuticals

The pharmaceutical industry is experiencing several key trends that can impact the pricing and market dynamics of drugs like Macrobid.

Drug Price Inflation

According to Vizient's summer Pharmacy Market Outlook, the overall drug price inflation rate for pharmaceuticals in 2025 is projected to be 3.81%. This inflation is driven by factors such as the expanding indications of previously approved medications and the introduction of high-cost cell and gene therapies[2].

Technological Advancements

The adoption of artificial intelligence (AI) and health technology is becoming more prevalent in the pharmaceutical industry. AI is expected to play a significant role in clinical development, data science, and decision-making processes. However, this trend is more relevant to new drug development and may not directly impact the pricing of established drugs like Macrobid[3].

Generic and Branded Drugs

The market for generic drugs is growing, especially as patents for blockbuster drugs expire. For instance, in the non-small cell lung cancer (NSCLC) market, the expiration of patents for drugs like Tarceva and Alimta has led to a significant increase in generic sales. While Macrobid is a branded drug, the presence of generic alternatives in the urinary tract infection treatment market could influence its pricing[4].

Price Projections

Given the general trends in the pharmaceutical market, here are some key points to consider for price projections of Macrobid:

Inflation Impact

With an expected drug price inflation rate of 3.81% in 2025, Macrobid's price is likely to increase accordingly. This inflation rate reflects broader market trends rather than specific changes in the demand or supply of Macrobid.

Competitive Landscape

The urinary tract infection treatment market has several competitors, including both branded and generic options. The presence of generic alternatives can put downward pressure on the prices of branded drugs like Macrobid. However, Macrobid's specific formulation and brand loyalty may help maintain its market position and pricing.

Regulatory and Market Factors

Regulatory changes and market dynamics can also impact pricing. For example, any changes in reimbursement policies or formulary listings could affect the demand and pricing of Macrobid.

Market Analysis

Demand and Supply

The demand for Macrobid is likely to remain stable given its established use in treating urinary tract infections. However, the supply side could be influenced by manufacturing costs, raw material availability, and competition from generic alternatives.

Competitive Positioning

Macrobid's competitive positioning is strong due to its brand recognition and specific formulation. However, the increasing availability of generic nitrofurantoin products may erode some of its market share.

Expert Insights

"The pharmaceutical industry is facing a complex landscape where technological advancements, regulatory changes, and economic pressures all play a role. For drugs like Macrobid, maintaining market share will depend on a combination of brand loyalty, competitive pricing, and strategic marketing efforts." - Dimitrios Skaltsas, Co-Founder and CEO of Intelligencia.ai[3].

Key Takeaways

  • Inflation Impact: Macrobid's price is expected to increase by approximately 3.81% in 2025 due to overall drug price inflation.
  • Competitive Landscape: The presence of generic alternatives may put downward pressure on Macrobid's price, but its brand recognition and specific formulation help maintain its market position.
  • Regulatory and Market Factors: Changes in reimbursement policies or formulary listings could impact the demand and pricing of Macrobid.
  • Technological Advancements: While AI and health technology are transforming the pharmaceutical industry, their direct impact on Macrobid's pricing is minimal.

FAQs

Q: What is the expected drug price inflation rate for 2025? A: The overall drug price inflation rate for pharmaceuticals in 2025 is projected to be 3.81%[2].

Q: How does the adoption of AI impact the pricing of Macrobid? A: The adoption of AI in the pharmaceutical industry is more relevant to new drug development and does not directly impact the pricing of established drugs like Macrobid[3].

Q: What is the competitive landscape for Macrobid? A: Macrobid competes with both branded and generic options in the urinary tract infection treatment market. The presence of generic alternatives can put downward pressure on its price[4].

Q: How do regulatory changes affect the pricing of Macrobid? A: Regulatory changes, such as changes in reimbursement policies or formulary listings, can impact the demand and pricing of Macrobid.

Q: What are the key factors influencing the market position of Macrobid? A: The key factors include brand recognition, competitive pricing, and strategic marketing efforts, as well as broader market trends like drug price inflation and the availability of generic alternatives.

Sources

  1. FDA.report - NDC 52427-285 Oral Capsule Macrobid Drug Codes.
  2. Vizient, Inc. - Vizient projects drug price inflation at 3.81%.
  3. Intelligencia.ai - 2025 Pharma Predictions: AI, Health Tech, and Data Trends to Watch.
  4. Drug-dev.com - NSCLC MARKET - Global Drug Forecast & Market Analysis to 2025.

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