Introduction
Dorzolamide HCL and Timolol Maleate, a combination ophthalmic solution, is widely used for the treatment of glaucoma and ocular hypertension. This article delves into the current market dynamics, price trends, and future projections for this medication, specifically focusing on the NDC code 61314-0030.
Current Market Pricing
As of the latest data, the wholesale price for Dorzolamide HCL 2% and Timolol Maleate 0.5% ophthalmic solution, manufactured by Sandoz Inc., is approximately $19.10 per 10ml bottle. This translates to a price per unit of $1.910 per ml[1].
Price Trends and Projections
Generic Drug Price Erosion
The generic drug industry, including ophthalmic solutions like Dorzolamide HCL and Timolol Maleate, is expected to experience mid-single-digit percent annual price erosion. This trend is driven by increased competition and market pressures, which can lead to modest revenue growth for generic drug manufacturers[3].
Overall Drug Price Inflation
Despite the expected price erosion in the generic segment, the overall drug price inflation is projected to grow at 3.8% in 2024, primarily driven by specialty pharmaceuticals. However, this inflation rate is less likely to impact generic ophthalmic solutions directly[4].
Regulatory and Transparency Factors
Drug Price Transparency
Programs like Oregon's Drug Price Transparency Program aim to provide accountability for prescription drug pricing. These programs require manufacturers to report price increases and provide detailed information on the reasons behind these increases. While such programs do not directly set prices, they can influence market dynamics by increasing transparency and potentially leading to more stable pricing[2].
Upper Payment Limits
There is a growing discussion around implementing upper payment limits for certain drugs, which could potentially affect the pricing of medications like Dorzolamide HCL and Timolol Maleate. However, this concept is still in its infancy, and no state has yet implemented such a limit[2].
Supply Chain and Market Dynamics
Pharmaceutical Supply Chain
The price of prescription drugs, including ophthalmic solutions, is influenced by various entities within the pharmaceutical supply chain, such as manufacturers, pharmacy benefit managers (PBMs), and health insurers. Regulatory oversight and reporting requirements can impact how these entities interact and influence drug prices[2].
Biosimilars and Generic Competition
While biosimilars are expected to grow in market share, particularly in the specialty pharmaceutical segment, their impact on generic ophthalmic solutions like Dorzolamide HCL and Timolol Maleate is likely to be minimal. However, increased competition from other generic manufacturers can still affect pricing[4].
Potential Risks and Challenges
Price-Fixing Litigation
The generic drug industry faces potential risks from price-fixing litigation, which could impact the pricing stability of drugs like Dorzolamide HCL and Timolol Maleate. Additionally, increased FDA inspections of foreign manufacturing facilities could lead to supply chain disruptions and price volatility[3].
Conclusion
The market for Dorzolamide HCL and Timolol Maleate, as represented by NDC code 61314-0030, is influenced by a complex interplay of factors including generic price erosion, overall drug price inflation, regulatory transparency, and supply chain dynamics.
- Current Pricing: The wholesale price is approximately $19.10 per 10ml bottle.
- Price Projections: Mid-single-digit percent annual price erosion is expected in the generic segment.
- Regulatory Impact: Transparency programs and potential upper payment limits could influence pricing stability.
- Supply Chain: Competition from other generics and biosimilars, along with regulatory oversight, will continue to shape the market.
Key Takeaways
- The current wholesale price for Dorzolamide HCL and Timolol Maleate is around $1.910 per ml.
- Generic drug price erosion is expected to continue, affecting revenue growth.
- Regulatory transparency programs and potential upper payment limits may impact pricing.
- Supply chain dynamics, including competition and regulatory oversight, are crucial factors.
FAQs
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What is the current wholesale price for Dorzolamide HCL and Timolol Maleate (NDC: 61314-0030)?
- The current wholesale price is approximately $19.10 per 10ml bottle, or $1.910 per ml[1].
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What are the expected price trends for generic ophthalmic solutions in 2024?
- Mid-single-digit percent annual price erosion is expected, leading to modest revenue growth[3].
-
How do regulatory transparency programs affect drug pricing?
- These programs increase accountability and transparency, potentially leading to more stable pricing by requiring detailed reporting from manufacturers[2].
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What is the impact of biosimilars on the pricing of generic ophthalmic solutions?
- The impact is likely minimal, as biosimilars primarily affect the specialty pharmaceutical segment[4].
-
What are some potential risks facing the generic drug industry in 2024?
- Price-fixing litigation and increased FDA inspections of foreign manufacturing facilities are potential risks[3].
Sources
- DrugPatentWatch - Drug prices and trends for DORZOLAMIDE HCL
- Oregon Department of Consumer and Business Services - Prescription Drug Price Transparency Results and Recommendations
- S&P Global - Pharmaceutical Industry 2024 Credit Outlook Is Stable As Revenue Growth Mitigates Pressures
- Vizient, Inc. - Vizient Projects 3.8% Drug Price Increase Driven by Specialty Pharmaceuticals
