Drug Sales Trends for TRADJENTA

Annual Sales Revenues and Units Sold for TRADJENTA

These sales figures are drawn from a US national survey of drug expenditures

Drug Name	Revenues (USD)	Units	Year
TRADJENTA			2021
TRADJENTA			2020
TRADJENTA			2019
TRADJENTA			2018
TRADJENTA			2017
TRADJENTA			2016

Market Analysis and Sales Projections for Tradjenta

Introduction

Tradjenta, also known as linagliptin, is a dipeptide peptidase 4 (DPP-4) inhibitor used in the treatment of type 2 diabetes. Developed by Boehringer Ingelheim and marketed by Boehringer Ingelheim and Eli Lilly, Tradjenta has been a significant player in the diabetes management market.

Market Overview

The global DPP-4 inhibitors market, which includes Tradjenta, was valued at USD 10.5 billion in 2018 and is expected to grow at a moderate rate. The market is driven by increasing prevalence of type 2 diabetes and obesity, as well as advancements in clinical trials for DPP-4 drugs[1].

Market Share and Growth

Tradjenta is anticipated to register a Compound Annual Growth Rate (CAGR) of 5.7% from 2019 to 2024, surpassing Merck's Januvia, which held the maximum market share in 2018. This growth is attributed to the effectiveness of Tradjenta and its combination products, such as Jentadueto and Jentadueto XR, which combine linagliptin with metformin hydrochloride[1].

Geographic Performance

North America holds the highest market share in the DPP-4 inhibitors market, followed by the Asia-Pacific region, which accounts for 32% of the global market share. Latin America is expected to register the highest CAGR of approximately 6% during the forecast period, driven by increasing diabetes prevalence and other health factors[1].

Competitive Landscape

In the competitive landscape, Merck held the highest market share in the DPP-4 market in 2018 but is expected to see a decline after 2022 due to the launch of generic versions of its drugs. Tradjenta, however, is poised to gain market share due to its robust safety profile and efficacy. Boehringer Ingelheim and Eli Lilly's strategic marketing and partnership efforts also contribute to Tradjenta's market position[1][3].

Sales Forecast

Sales forecasts for Tradjenta are positive, with the drug expected to be one of the dominant segments in the DPP-4 inhibitors market. For the period from 2012 to 2022, sales forecasts indicated significant growth, particularly in key markets such as the US, France, Germany, Italy, Spain, the UK, Japan, Brazil, India, and China[3].

Clinical Trials and Safety Profile

Recent comprehensive research involving nearly 7,000 adults with type 2 diabetes and established heart and/or kidney disease has shown that Tradjenta does not increase the risk of major cardiovascular events compared to a placebo. This robust safety profile enhances its market position and makes it a reliable choice for diabetes management[4].

Market Drivers

• Increasing Prevalence of Diabetes: The rising number of diabetes cases, especially among younger generations, is a significant driver. A CDC study forecasts a substantial increase in type 2 diabetes cases among young people in the U.S. from 2017 to 2060[4].
• Innovative Treatment Solutions: Continuous development of innovative treatment solutions, such as combination therapies and novel branded drugs, drives market growth[3].
• Demographic Factors: Lowering birth rates and increasing life expectancy in countries with a high percentage of the geriatric population also contribute to market growth[1].

Market Restraints

• Generic Competition: The expected launch of generic versions of existing DPP-4 inhibitors, such as Merck's Sitagliptin in 2022, could pose a challenge to branded drugs like Tradjenta[1].
• Regulatory Decisions: Decisions by reimbursement authorities, such as the one in Germany that concluded Tradjenta does not provide additional benefits compared to existing medicines, can impact market performance[1].

Future Trends

The DPP-4 inhibitors market is poised for growth due to the increasing prevalence of diabetes and the need for effective and safe treatment options. Tradjenta's strong safety profile and efficacy make it a promising candidate to capitalize on these trends. Additionally, the market is expected to benefit from advancements in pediatric diabetes treatment, as highlighted by successful trials like AstraZeneca's Forxiga in the T2NOW Phase III trial[4].

Key Takeaways

• Tradjenta is expected to surpass Januvia in market share by 2024.
• The drug has a robust safety profile and does not increase the risk of major cardiovascular events.
• Increasing diabetes prevalence, especially among younger generations, drives market growth.
• North America and the Asia-Pacific region are key markets for Tradjenta.
• Generic competition and regulatory decisions are potential restraints.

FAQs

Q: What is Tradjenta used for? A: Tradjenta, or linagliptin, is used in the treatment of type 2 diabetes.

Q: Who markets Tradjenta? A: Tradjenta is marketed by Boehringer Ingelheim and Eli Lilly.

Q: What is the expected growth rate of Tradjenta from 2019 to 2024? A: Tradjenta is expected to register a CAGR of 5.7% from 2019 to 2024.

Q: Which region holds the highest market share for DPP-4 inhibitors? A: North America holds the highest market share in the DPP-4 inhibitors market.

Q: What are the main drivers of the DPP-4 inhibitors market? A: The main drivers include increasing diabetes prevalence, innovative treatment solutions, and demographic factors such as aging populations.

Sources

1. Dipeptide Peptidase 4 (DPP-4) Inhibitors: Global Market 2019-2024 - ResearchAndMarkets.com
2. Lilly Reports Strong Fourth-Quarter 2023 Financial Results and Provides 2024 Guidance - PR Newswire
3. Tradjenta (Type 2 Diabetes) - Forecast and Market Analysis to 2022 - Business Wire
4. Dipeptide Peptidase 4 Inhibitors Market Size Report, 2030 - Grand View Research