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Last Updated: January 7, 2025

CLINICAL TRIALS PROFILE FOR APAZIQUONE

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Clinical Trials for Apaziquone

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00141531 ↗	Phase II Trial of EOquin in High-risk Superficial Bladder Cancer	Completed	Spectrum Pharmaceuticals, Inc	Phase 2	A non-randomized, open-label phase II study to explore the feasibility, time to recurrence, duration of response and safety of the adjuvant intravesical instillation of EOquin (apaziquone) in patients with high-risk superficial bladder tumors, and the response and duration of response in patients with carcinoma in situ of the bladder.
NCT00461591 ↗	Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-611)	Completed	Spectrum Pharmaceuticals, Inc	Phase 3	The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus those who received TURBT plus placebo.
NCT00598806 ↗	Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-612)	Completed	Spectrum Pharmaceuticals, Inc	Phase 3	The purpose of this study was to evaluate the 2-Year Recurrence Rate of bladder cancer in randomized patients with tumor histology Ta, G1-G2 who received TransUrethral Resection of Bladder Tumor (TURBT) plus apaziquone versus those who received TURBT plus placebo.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Apaziquone

Condition Name

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Condition Name
Intervention	Trials
Bladder Cancer	8
Bladder Neoplasms	1
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Condition MeSH

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Condition MeSH
Intervention	Trials
Urinary Bladder Neoplasms	9
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Clinical Trial Locations for Apaziquone

Trials by Country

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Trials by Country
Location	Trials
United States	69
Canada	11
Japan	7
Korea, Republic of	2
Poland	2
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Trials by US State

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Trials by US State
Location	Trials
New York	4
New Jersey	4
California	4
Virginia	3
Texas	3
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Clinical Trial Progress for Apaziquone

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	6
Phase 2/Phase 3	1
Phase 2	1
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Terminated	5
Completed	4
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Clinical Trial Sponsors for Apaziquone

Sponsor Name

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Sponsor Name
Sponsor	Trials
Spectrum Pharmaceuticals, Inc	7
Handok Inc.	2
Handok Pharmaceuticals Co., Ltd.	2
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Industry	15
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