CLINICAL TRIALS PROFILE FOR BAY2433334

Clinical Trials for BAY2433334

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT04218266 ↗	Study to Gather Information About the Proper Dosing of the Oral FXIa Inhibitor BAY 2433334 and to Compare the Safety of the Study Drug to Apixaban, a Non-vitamin K Oral Anticoagulant (NOAC) in Patients With Irregular Heartbeat (Atrial Fibrillation)	Completed	Bayer	Phase 2	The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works in patients with irregular heartbeat (atrial fibrillation) that can lead to blood clots, stroke and other heart-related complications. In addition researchers want to compare the safety of the study drug to apixaban, a non-vitamin K oral anticoagulant (NOAC) in patients with atrial fibrillation. This study is also done to learn how the drug in this study moves into, through and out of the body. BAY 2433334, works by blocking a step of the blood clotting process in our body and thins the blood and is a so called oral FXIa inhibitor. Apixaban, works by reducing the production of blood clotting factors in our body and thins the blood and is a so called non-vitamin K oral anticoagulant (NOAC). Thinning the blood can prevent you from blood clots which can cause a stroke.
NCT04304508 ↗	Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the	Active, not recruiting	Population Health Research Institute	Phase 2	The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of antiplatelet therapy in patients following a recent non cardioembolic ischemic stroke which occurs when a blood clot that has not formed in the heart travelled to the brain. BAY 2433334, works by blocking a step of the blood clotting process in our body and thins the blood and is a so called oral FXIa inhibitor.
NCT04304508 ↗	Study to Gather Information About Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following a Recent Non Cardioembolic Ischemic Stroke Which Occurs When a Blood Clot Has Formed Somewhere in the Human Body (But Not in the	Active, not recruiting	Bayer	Phase 2	The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of antiplatelet therapy in patients following a recent non cardioembolic ischemic stroke which occurs when a blood clot that has not formed in the heart travelled to the brain. BAY 2433334, works by blocking a step of the blood clotting process in our body and thins the blood and is a so called oral FXIa inhibitor.
NCT04304534 ↗	Study to Gather Information About the Proper Dosing and Safety of the Oral FXIa Inhibitor BAY 2433334 in Patients Following an Acute Heart Attack	Active, not recruiting	Bayer	Phase 2	The purpose of this study is to try to find the best dose of the new drug BAY 2433334 to give to participants and to look at how well BAY 2433334 works on top of a dual antiplatelet therapy (acetylsalicylic acid +/- clopidogrel) in patients following a recent heart attack (myocardial infarction) that happens when a blood vessel in the heart suddenly becomes blocked. BAY 2433334, works by blocking a step of the blood clotting process in our body and thins the blood and is a so called oral FXIa inhibitor.

Clinical Trial Conditions for BAY2433334

Condition Name

Condition Name
Intervention	Trials
Prevention of Thromboembolic Events	2
Acute Myocardial Infarction	2
Acute Non-cardioembolic Ischemic Stroke	2
Atrial Fibrillation	2

Condition MeSH

Condition MeSH
Intervention	Trials
Atrial Fibrillation	3
Stroke	3
Ischemic Stroke	3
Thromboembolism	2

Clinical Trial Locations for BAY2433334

Trials by Country

Trials by Country
Location	Trials
United States	81
Japan	56
China	50
Italy	45
United Kingdom	39

Trials by US State

Trials by US State
Location	Trials
Pennsylvania	4
Minnesota	4
Florida	4
Texas	3
Tennessee	3

Clinical Trial Progress for BAY2433334

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	3
Phase 1	2

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Active, not recruiting	3
Not yet recruiting	3
Completed	1

Clinical Trial Sponsors for BAY2433334

Sponsor Name

Sponsor Name
Sponsor	Trials
Bayer	7
Population Health Research Institute	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	7
Other	1