CLINICAL TRIALS PROFILE FOR BLD-0409

Clinical Trials for BLD-0409

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT04146805 ↗	Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Subjects	Completed	Blade Therapeutics	Phase 1	A Phase 1a, Double Blind, Placebo-Controlled, Single-Center, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of BLD-0409 in Healthy Volunteers
NCT04814472 ↗	Healthy Volunteer Study Comparing Tablet and Oral Solution Formulations	Completed	Blade Therapeutics	Phase 1	A Two-Part, Open-Label, Crossover, Bioavailability Study Comparing Tablet and Oral Solution Formulations of BLD-0409 in Healthy Volunteers
NCT04814498 ↗	Drug-Drug Interaction (DDI) Study in Healthy Volunteers	Active, not recruiting	Blade Therapeutics	Phase 1	A Phase 1, Open Label, Fixed Sequence Study to Evaluate the Effect of BLD-0409 on the Single Dose Pharmacokinetics of a Cocktail of Probe Substrates for CYP450 Enzymes in Healthy Volunteers
NCT04939467 ↗	Dedicated Drug-Drug Interaction (DDI) Study in Healthy Volunteers	Recruiting	Blade Therapeutics	Phase 1	A Phase 1, Open-Label, Non-Randomized, Fixed Sequence Study to Evaluate the Steady-state Pharmacokinetics of BLD-0409, Nintedanib and Pirfenidone when Administered Concurrently in Healthy Volunteers
NCT05373914 ↗	RESPIRARE Phase 2 Study of Efficacy and Safety of Cudetaxestat in Patients With Idiopathic Pulmonary Fibrosis (IPF)	Not yet recruiting	Blade Therapeutics	Phase 2	The overall objective of this study is to evaluate the effectiveness and safety of cudetaxestat (BLD-0409) as compared to placebo with or without standard of care (nintedanib or pirfenidone) in subjects with idiopathic pulmonary fibrosis (IPF)

Clinical Trial Conditions for BLD-0409

Condition Name

Condition Name
Intervention	Trials
Drug Drug Interaction	2
NASH - Nonalcoholic Steatohepatitis	1
Relative Bioavailability	1
Chronic Liver Disease	1

Condition MeSH

Condition MeSH
Intervention	Trials
Fibrosis	1
Non-alcoholic Fatty Liver Disease	1
Liver Diseases	1
Fatty Liver	1

Clinical Trial Locations for BLD-0409

Trials by Country

Trials by Country
Location	Trials
Australia	4
United States	1

Trials by US State

Trials by US State
Location	Trials
Florida	1

Clinical Trial Progress for BLD-0409

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	1
Phase 1	4

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	2
Recruiting	1
Active, not recruiting	1

Clinical Trial Sponsors for BLD-0409

Sponsor Name

Sponsor Name
Sponsor	Trials
Blade Therapeutics	5

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	5