CLINICAL TRIALS PROFILE FOR BASIMGLURANT

Clinical Trials for Basimglurant

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02433093 ↗	A Study of the Safety, Tolerability, and Pharmacokinetics of Multiple-Ascending Dose Basimglurant in Healthy Subjects and in Patients With Major Depressive Disorder (MDD)	Completed	Hoffmann-La Roche	Phase 1	The study will assess the safety, tolerability, and pharmacokinetics of basimglurant compared to placebo after multiple ascending oral doses for up to 22 days in healthy subjects and in patients with MDD on stable selective serotonin reuptake inhibitor (SSRI) or serotonin-norepinephrine reuptake inhibitor (SNRI) background therapy.
NCT05059327 ↗	Basimglurant in Children and Adolescents With TSC	Not yet recruiting	Noema Pharma AG	Phase 2	The study intends to show that basimglurant provides effective seizure control in children and adolescents with Tuberous Sclerosis Complex (TSC).
NCT05217628 ↗	An Efficacy and Safety Study of Basimglurant in Patients With Trigeminal Neuralgia.	Recruiting	Noema Pharma AG	Phase 2/Phase 3	Trigeminal neuralgia (TN), also called "tic douloureux", is the most common form of craniofacial neuropathic pain and is considered the cause of one of the most painful afflictions known in medical practice. This study is designed to evaluate the efficacy and safety of 1.5mg - 3.5mg basimglurant in adults with TN.

Clinical Trial Conditions for Basimglurant

Condition Name

Condition Name
Intervention	Trials
Major Depressive Disorder, Healthy Volunteer	1
Trigeminal Neuralgia	1
Tuberous Sclerosis Complex	1

Condition MeSH

Condition MeSH
Intervention	Trials
Sclerosis	1
Disease	1
Depressive Disorder, Major	1
Depressive Disorder	1

Clinical Trial Locations for Basimglurant

Trials by Country

Trials by Country
Location	Trials
United States	6

Trials by US State

Trials by US State
Location	Trials
California	2
Nevada	1
Massachusetts	1
Illinois	1
Florida	1

Clinical Trial Progress for Basimglurant

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2/Phase 3	1
Phase 2	1
Phase 1	1

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Recruiting	1
Completed	1
Not yet recruiting	1

Clinical Trial Sponsors for Basimglurant

Sponsor Name

Sponsor Name
Sponsor	Trials
Noema Pharma AG	2
Hoffmann-La Roche	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	3