CLINICAL TRIALS PROFILE FOR CA-008

Clinical Trials for CA-008

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT03307837 ↗	A Phase 1 Study of Intraoperative Administration of CA-008 for the Correction of Hallux Valgus Deformity	Completed	Concentric Analgesics	Phase 1	This is a single-center, randomized, double-blind, placebo-controlled, single ascending dose, sequential-group Phase 1 study. The study will be conducted utilizing a cohort design, with sequential groups of 8 subjects. Within each dose cohort, 6 subjects will be randomized to active, and 2 will be randomized to placebo.
NCT03599089 ↗	Study of CA-008 (Vocacapsaicin) in Bunionectomy Patients	Completed	Concentric Analgesics	Phase 2	This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study evaluating a single dose of one of three CA-008 dose levels vs. placebo injected during an elective bunionectomy Bunionectomy to assess post-surgical pain management and the need for rescue medication (oxycodone).
NCT03731364 ↗	Pain Study in Total Knee Arthroplasty	Completed	Concentric Analgesics	Phase 2	This is a Phase 2, multi-center, randomized, double-blind, placebo-controlled, parallel design study of CA-008 vs. placebo injected/instilled during an elective TKA.

Clinical Trial Conditions for CA-008

Condition Name

Condition Name
Intervention	Trials
Post-surgical Pain	2
Postsurgical Pain	2
Acute Post-surgical Pain	1

Condition MeSH

Condition MeSH
Intervention	Trials
Pain, Postoperative	5
Hallux Valgus	1
Congenital Abnormalities	1

Clinical Trial Locations for CA-008

Trials by Country

Trials by Country
Location	Trials
United States	10

Trials by US State

Trials by US State
Location	Trials
California	5
Texas	4
Maryland	1

Clinical Trial Progress for CA-008

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	4
Phase 1/Phase 2	2
Phase 1	1

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	6
Active, not recruiting	1

Clinical Trial Sponsors for CA-008

Sponsor Name

Sponsor Name
Sponsor	Trials
Concentric Analgesics	7

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	7