CLINICAL TRIALS PROFILE FOR CLEMIZOLE

Clinical Trials for Clemizole

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00945880 ↗	Safety and Tolerability Study of Clemizole Hydrochloride to Treat Hepatitis C in Subjects Who Are Treatment-Naive	Completed	Eiger BioPharmaceuticals	Phase 1	The purpose of this study is to test the hypothesis that clemizole hydrochloride is safe and well tolerated when administered to subjects who are infected with hepatitis C virus and have not yet received treatment. This study will also examine how the virus and body respond to clemizole hydrochloride.
NCT04069689 ↗	Study of Safety and Pharmacokinetics of Oral Doses of EPX-100 in Healthy Subjects.	Completed	Epygenix	Phase 1	This is a placebo-controlled, double-blind, 2-period study in 3 sequential groups of 8 healthy subjects each. The safety and pharmacokinetics of escalating single and multiple oral doses of EPX-100 will be assessed in fasting healthy subjects and following a high-fat meal.
NCT04462770 ↗	EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome	Recruiting	GreenLight Clinical PTY LTD	Phase 2	The purpose of this study is to compare the efficacy of EPX-100 against placebo as adjunctive therapy in 60 patients with Dravet Syndrome.
NCT04462770 ↗	EPX-100 (Clemizole Hydrochloride) as Add-on Therapy to Control Convulsive Seizures in Patients With Dravet Syndrome	Recruiting	Epygenix	Phase 2	The purpose of this study is to compare the efficacy of EPX-100 against placebo as adjunctive therapy in 60 patients with Dravet Syndrome.

Clinical Trial Conditions for Clemizole

Condition Name

Condition Name
Intervention	Trials
Dravet Syndrome	2
Lennox Gastaut Syndrome	1
Hepatitis C	1

Condition MeSH

Condition MeSH
Intervention	Trials
Syndrome	2
Epilepsies, Myoclonic	2
Lennox Gastaut Syndrome	1
Hepatitis C	1

Clinical Trial Locations for Clemizole

Trials by Country

Trials by Country
Location	Trials
United States	4

Trials by US State

Trials by US State
Location	Trials
New Jersey	2
Texas	1
Tennessee	1

Clinical Trial Progress for Clemizole

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	2
Phase 1	2

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	2
Not yet recruiting	1
Recruiting	1

Clinical Trial Sponsors for Clemizole

Sponsor Name

Sponsor Name
Sponsor	Trials
Epygenix	3
GreenLight Clinical PTY LTD	1
Eiger BioPharmaceuticals	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	4
Other	1