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Last Updated: December 14, 2024

CLINICAL TRIALS PROFILE FOR EMODEPSIDE

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Clinical Trials for Emodepside

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT02661178 ↗	First in Man Clinical Trial of Emodepside (BAY 44-4400)	Completed	Bayer	Phase 1	This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers. This study will also conduct an exploratory investigation of the relative bioavailability of emodepside administered as tablets and determine the effect of food on the pharmacokinetics.
NCT02661178 ↗	First in Man Clinical Trial of Emodepside (BAY 44-4400)	Completed	Bill and Melinda Gates Foundation	Phase 1	This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers. This study will also conduct an exploratory investigation of the relative bioavailability of emodepside administered as tablets and determine the effect of food on the pharmacokinetics.
NCT02661178 ↗	First in Man Clinical Trial of Emodepside (BAY 44-4400)	Completed	Drugs for Neglected Diseases	Phase 1	This study will investigate the safety, tolerability, and pharmacokinetics of single ascending doses of emodepside (BAY 44-4400) in healthy male volunteers. This study will also conduct an exploratory investigation of the relative bioavailability of emodepside administered as tablets and determine the effect of food on the pharmacokinetics.
NCT03383523 ↗	Relative Bioavailability Study of Emodepside IR-tablets and Solution	Completed	Bayer	Phase 1	This study evaluates 2 new immediate release (IR)-tablet formulations of emodepside and they will be compared to the oral liquid service formulation (LSF) used in the FIH Single Ascending Dose study (DNDi-EMO-001 study) (CT.gov identifier: NCT02661178)
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Emodepside

Condition Name

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Condition Name
Intervention	Trials
Filariasis	2
Hookworm Infections	2
Healthy Volunteers	1
Onchocerciasis	1
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Condition MeSH

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Condition MeSH
Intervention	Trials
Ancylostomiasis	2
Filariasis	2
Hookworm Infections	2
Communicable Diseases	1
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Clinical Trial Locations for Emodepside

Trials by Country

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Trials by Country
Location	Trials
United Kingdom	3
Tanzania	2
Ghana	1
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Clinical Trial Progress for Emodepside

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	3
Phase 1	3
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Completed	3
Recruiting	2
Not yet recruiting	1
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Clinical Trial Sponsors for Emodepside

Sponsor Name

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Sponsor Name
Sponsor	Trials
Bayer	4
Drugs for Neglected Diseases	4
Bill and Melinda Gates Foundation	3
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Other	11
Industry	4
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