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Last Updated: December 11, 2024

CLINICAL TRIALS PROFILE FOR ERITORAN

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Clinical Trials for Eritoran

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00334828 ↗	ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis	Completed	Eisai Inc.	Phase 3	The purpose of this study is to compare eritoran tetrasodium and placebo in patients with severe sepsis and to demonstrate a reduction of mortality from all causes.
NCT00756912 ↗	A Study of Eritoran (E5564) Administered IV Over 14 Days Prior to and During Bone Marrow Engraftment in BMT Patients Who Have Received Myeloablative Conditioning Treatment and Are Receiving Bone Marrow or Stem Cells From Matched Related Donors	Terminated	Eisai Inc.	Phase 1	This is a study designed to assess the safety of administration of up to 3 dose levels of eritoran in subjects undergoing or scheduled to undergo allogeneic bone marrow transplant (BMT). An allogeneic BMT is the transplantation of blood stem cells taken from the bone marrow or blood of another person.
NCT02267317 ↗	The Effect of TLR4 Inhibition in Obese and Type 2 Diabetic Subjects	Terminated	Nicolas Musi	Phase 2	To determine whether pharmacologic inhibition of Toll-like receptor 4 (TLR4) with eritoran for injection (E5564) will reduce inflammation and improve glucose metabolism in insulin resistant (obese and T2DM) subjects.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Eritoran

Condition Name

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Condition Name
Intervention	Trials
Insulin Sensitivity	2
Severe Sepsis	1
Community Acquired Pneumonia	1
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Condition MeSH

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Condition MeSH
Intervention	Trials
Insulin Resistance	2
Hypersensitivity	2
COVID-19	1
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Clinical Trial Locations for Eritoran

Trials by Country

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Trials by Country
Location	Trials
United States	37
Australia	12
Canada	8
France	2
Ireland	2
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Trials by US State

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Trials by US State
Location	Trials
Texas	3
Pennsylvania	2
Ohio	2
Missouri	1
Michigan	1
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Clinical Trial Progress for Eritoran

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 4	1
Phase 3	1
Phase 2	2
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Terminated	2
Completed	2
Recruiting	1
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Clinical Trial Sponsors for Eritoran

Sponsor Name

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Sponsor Name
Sponsor	Trials
Eisai Inc.	2
The University of Texas Health Science Center at San Antonio	2
Australian and New Zealand Intensive Care Research Centre	1
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Other	11
Industry	2
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