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Last Updated: January 5, 2025

CLINICAL TRIALS PROFILE FOR FAMITINIB

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Clinical Trials for Famitinib

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01392235 ↗	Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)	Completed	Sun Yat-sen University	Phase 2	RATIONALE: Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3. Phase I study has shown that the drug's toxicity is manageable. PURPOSE: This phase II trial is studying how well famitinib works in treating patients with recurrent and/or metastatic NPC.
NCT01392235 ↗	Famitinib in Treating Patients With Recurrent and/or Metastatic Nasopharyngeal Carcinoma (NPC)	Completed	Jiangsu HengRui Medicine Co., Ltd.	Phase 2	RATIONALE: Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3. Phase I study has shown that the drug's toxicity is manageable. PURPOSE: This phase II trial is studying how well famitinib works in treating patients with recurrent and/or metastatic NPC.
NCT01462474 ↗	Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal Carcinoma	Completed	Sun Yat-sen University	Phase 1	RATIONALE: Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3. Phase I study of mono famitinib has shown that the drug's toxicity is manageable. PURPOSE: This phase I trial is studying the safety and tolerance of concurrent chemoradiotherapy with famitinib for patients with locally advanced nasopharyngeal carcinoma.
NCT01462474 ↗	Concurrent Chemoradiotherapy With Famitinib for Patients With Locally Advanced Nasopharyngeal Carcinoma	Completed	Jiangsu HengRui Medicine Co., Ltd.	Phase 1	RATIONALE: Famitinib is a tyrosin-inhibitor agent targeting at c-Kit, VEGFR2, PDGFR, VEGFR3, Flt1 and Flt3. Phase I study of mono famitinib has shown that the drug's toxicity is manageable. PURPOSE: This phase I trial is studying the safety and tolerance of concurrent chemoradiotherapy with famitinib for patients with locally advanced nasopharyngeal carcinoma.
NCT01653574 ↗	A Study of Famitinib Malate in HER2-negative Metastatic Breast Cancer	Completed	Jiangsu HengRui Medicine Co., Ltd.	Phase 2	The hypothesis of this clinical research study is to discover if the study drug Famitinib Malate can shrink or slow the growth of pretreated HER2-negative metastatic breast cancer.
NCT01653574 ↗	A Study of Famitinib Malate in HER2-negative Metastatic Breast Cancer	Completed	Fudan University	Phase 2	The hypothesis of this clinical research study is to discover if the study drug Famitinib Malate can shrink or slow the growth of pretreated HER2-negative metastatic breast cancer.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Famitinib

Condition Name

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Condition Name
Intervention	Trials
Solid Tumor	4
Triple-Negative Breast Cancer	3
TNBC - Triple-Negative Breast Cancer	2
Advanced Solid Tumor	2
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Condition MeSH

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Condition MeSH
Intervention	Trials
Breast Neoplasms	11
Lung Neoplasms	7
Carcinoma, Non-Small-Cell Lung	6
Carcinoma	5
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Clinical Trial Locations for Famitinib

Trials by Country

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Trials by Country
Location	Trials
China	55
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Clinical Trial Progress for Famitinib

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	7
Phase 2	26
Phase 1/Phase 2	4
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Not yet recruiting	22
Completed	10
Recruiting	8
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Clinical Trial Sponsors for Famitinib

Sponsor Name

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Sponsor Name
Sponsor	Trials
Jiangsu HengRui Medicine Co., Ltd.	38
Fudan University	9
Sun Yat-sen University	4
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Sponsor Type

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Sponsor Type
Sponsor	Trials
Industry	38
Other	26
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