CLINICAL TRIALS PROFILE FOR IFETROBAN

Clinical Trials for Ifetroban

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT01436500 ↗	Safety and Pharmacokinetics of Ifetroban in Hepatorenal Syndrome Patients	Completed	Cumberland Pharmaceuticals	Phase 2	A study of ifetroban in the treatment of hepatorenal syndrome (HRS) in hospitalized adult patients to assess the safety and pharmacokinetics of 3 days of intravenous ifetroban.
NCT02216357 ↗	Trial to Determine the Safety of Oral Ifetroban in Patients With a History of Aspirin Exacerbated Respiratory Disease	Completed	Cumberland Pharmaceuticals	Phase 2	The primary objective of the study is to determine the safety of oral ifetroban compared to placebo as measured by a > 20% decrease in FEV1 compared to baseline following a dose of Investigational Medicinal Product (IMP) (Study Day 1 or 2) prior to initiation of the aspirin challenge.
NCT02682511 ↗	Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension	Recruiting	Cumberland Pharmaceuticals	Phase 2	The purpose of this phase 2 multicenter, randomized, double-blind, placebo-controlled, study is to assess the safety and efficacy of ifetroban in patients with diffuse cutaneous systemic SSc (dcSSc) or SSc-associated pulmonary arterial hypertension (SSc-PAH).

Clinical Trial Conditions for Ifetroban

Condition Name

Condition Name
Intervention	Trials
Asthma, Aspirin-Induced	2
Postneoadjuvant Therapy Stage II Esophageal Squamous Cell Carcinoma	1
Autoimmune Diseases	1

Condition MeSH

Condition MeSH
Intervention	Trials
Respiratory Tract Diseases	3
Respiration Disorders	3
Asthma, Aspirin-Induced	2

Clinical Trial Locations for Ifetroban

Trials by Country

Trials by Country
Location	Trials
United States	57
India	3

Trials by US State

Trials by US State
Location	Trials
California	5
Texas	4
Ohio	4
New York	4
Indiana	4

Clinical Trial Progress for Ifetroban

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	10

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Recruiting	6
Completed	3
Not yet recruiting	1

Clinical Trial Sponsors for Ifetroban

Sponsor Name

Sponsor Name
Sponsor	Trials
Cumberland Pharmaceuticals	9
Brigham and Women's Hospital	1
Vanderbilt University Medical Center	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	9
Other	5