CLINICAL TRIALS PROFILE FOR LYSERGIC ACID DIETHYLAMIDE

Clinical Trials for Lysergic acid diethylamide

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00920387 ↗	Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety	Completed	Multidisciplinary Association for Psychedelic Studies	Phase 2	This study will find out whether psychotherapy combined with lysergic acid diethylamide (LSD) is safe and is helpful in people who are anxious because they have a potentially fatal disease. The study will measure anxiety and quality of life before and after people have two sessions with either full or active placebo dose of LSD. They expect LSD-assisted psychotherapy to reduce anxiety and improve quality of life.
NCT01878942 ↗	Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study	Completed	University Hospital, Basel, Switzerland	Early Phase 1	The purpose of this study is to characterize the acute psychological, physiological, endocrine, and pharmacokinetic, as well as long-term psychological effects of LSD in humans.
NCT02308969 ↗	Neuronal Correlates of Altered States of Consciousness	Completed	University Hospital, Basel, Switzerland	Early Phase 1	The aim of the present study is to assess the neuronal correlates of alterations in waking consciousness pharmacologically induced by a 5-hydroxytryptamine (HT)2A receptor agonist in healthy subjects using functional magnetic resonance imaging (fMRI).
NCT02451072 ↗	The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers	Completed	Psychiatric University Hospital, Zurich	N/A	Aim of the present study is to investigate the neuronal correlates of self and of personal meaning as well as the role of the serotonin (5-HT) 2A receptor system in these processes using functional magnetic resonance imaging (fMRI) and psychometric and cognitive measures.
NCT03019822 ↗	Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing	Completed	University Hospital, Basel, Switzerland	Early Phase 1	The study will test the effect of dopamine, serotonin, and direct 5-HT2A receptor stimulation on empathy, mood perception, and amygdala activity to fearful stimuli. In addition, we predict associations between subjective effects/alterations in emotion processing tests and functional imaging (fMRI) activity.

Clinical Trial Conditions for Lysergic acid diethylamide

Condition Name

Condition Name
Intervention	Trials
Healthy	12
Anxiety	2
Major Depressive Disorder	1
Basic Science	1

Condition MeSH

Condition MeSH
Intervention	Trials
Headache	2
Cluster Headache	2
Caregiver Burden	1
Depressive Disorder, Major	1

Clinical Trial Locations for Lysergic acid diethylamide

Trials by Country

Trials by Country
Location	Trials
Switzerland	12
Netherlands	1
United States	1
Denmark	1
United Kingdom	1

Trials by US State

Trials by US State
Location	Trials
Illinois	1

Clinical Trial Progress for Lysergic acid diethylamide

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	5
Phase 1/Phase 2	1
Phase 1	8

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	9
Not yet recruiting	5
Recruiting	5

Clinical Trial Sponsors for Lysergic acid diethylamide

Sponsor Name

Sponsor Name
Sponsor	Trials
University Hospital, Basel, Switzerland	11
Eleusis Therapeutics	2
Canisius-Wilhelmina Hospital	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Other	24
Industry	2