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Last Updated: July 16, 2024

CLINICAL TRIALS PROFILE FOR ONC201


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Clinical Trials for ONC201

Trial ID Title Status Sponsor Phase Summary
NCT02038699 ↗ A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer Withdrawn Chimerix Phase 1/Phase 2 ONC201 is a new potential drug that kills cancer cells but not normal cells in laboratory studies. This clinical trial will be the first evaluation of ONC201 in humans and will enroll patients with advanced cancer. This trial includes a phase I portion that will evaluate the safety of ONC201 and the recommended dose for the phase II portion. The phase II portion will evaluate the initial efficacy profile of ONC201 in select types of cancer.
NCT02038699 ↗ A First-in-man Phase I/II Study of Oral ONC201 in Patients With Advanced Cancer Withdrawn Oncoceutics, Inc. Phase 1/Phase 2 ONC201 is a new potential drug that kills cancer cells but not normal cells in laboratory studies. This clinical trial will be the first evaluation of ONC201 in humans and will enroll patients with advanced cancer. This trial includes a phase I portion that will evaluate the safety of ONC201 and the recommended dose for the phase II portion. The phase II portion will evaluate the initial efficacy profile of ONC201 in select types of cancer.
NCT02250781 ↗ Oral ONC201 in Treating Patients With Advanced Solid Tumors Completed National Cancer Institute (NCI) Phase 1 This phase I trial studies the side effects and best dose of Oral ONC201 in treating patients with advanced solid tumors. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02250781 ↗ Oral ONC201 in Treating Patients With Advanced Solid Tumors Completed Rutgers Cancer Institute of New Jersey Phase 1 This phase I trial studies the side effects and best dose of Oral ONC201 in treating patients with advanced solid tumors. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02250781 ↗ Oral ONC201 in Treating Patients With Advanced Solid Tumors Completed Rutgers, The State University of New Jersey Phase 1 This phase I trial studies the side effects and best dose of Oral ONC201 in treating patients with advanced solid tumors. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02324621 ↗ Continuation of Oral ONC201 in Treating Patients With Advanced Solid Tumors Completed National Cancer Institute (NCI) Phase 1 This phase I trial studies the long-term side effects of the continuation of oral ONC201 in treating patients with solid tumors that have spread to other places in the body who have previously benefited from receiving this drug. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
NCT02324621 ↗ Continuation of Oral ONC201 in Treating Patients With Advanced Solid Tumors Completed Oncoceutics, Inc. Phase 1 This phase I trial studies the long-term side effects of the continuation of oral ONC201 in treating patients with solid tumors that have spread to other places in the body who have previously benefited from receiving this drug. Oral ONC201 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for ONC201

Condition Name

Condition Name
Intervention Trials
Glioblastoma 3
Diffuse Intrinsic Pontine Glioma 3
Multiple Myeloma 3
Endometrial Cancer 3
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Condition MeSH

Condition MeSH
Intervention Trials
Glioma 7
Glioblastoma 5
Endometrial Neoplasms 4
Neoplasms 3
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Clinical Trial Locations for ONC201

Trials by Country

Trials by Country
Location Trials
United States 47
France 1
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Trials by US State

Trials by US State
Location Trials
California 6
Pennsylvania 5
Michigan 4
New York 4
Texas 4
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Clinical Trial Progress for ONC201

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase Trials
Phase 3 2
Phase 2 10
Phase 1/Phase 2 6
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Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase Trials
Recruiting 8
Not yet recruiting 5
Active, not recruiting 4
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Clinical Trial Sponsors for ONC201

Sponsor Name

Sponsor Name
Sponsor Trials
Oncoceutics, Inc. 15
Chimerix 11
National Cancer Institute (NCI) 7
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Sponsor Type

Sponsor Type
Sponsor Trials
Other 31
Industry 28
NIH 7
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