Phase 1 TAK-925 Study in Healthy Adult and Elderly Volunteers and Participants With Narcolepsy
Completed
Takeda
Phase 1
The purpose of this study is to investigate safety, tolerability, and pharmacokinetics of
TAK-925 when a single dose of TAK-925 is administered to healthy adult participants, healthy
elderly participants and patients with type 1 narcolepsy.
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of TAK-925 Study in Sleep-Deprived Healthy Adults
Completed
Takeda
Phase 1
The purpose of this study is to determine the effect of TAK-925 after a single intravenous
dose (compared to placebo) on promoting wakefulness as measured by sleep latency on the
maintenance of wakefulness (MWT) in sleep-deprived healthy participants.
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-925 in Healthy Volunteers and Participants With Narcolepsy
Completed
Takeda
Phase 1
The purpose of this study is to investigate the safety, tolerability, pharmacokinetics, and
pharmacodynamics of TAK-925 when administered to healthy participants and narcolepsy
participants.
Study of TAK-925 in Participants With Obstructive Sleep Apnea (OSA) Who Are Experiencing Excessive Daytime Sleepiness (EDS) Despite Adequate Use of Continuous Positive Airway Pressure (CPAP)
Completed
Millennium Pharmaceuticals, Inc.
Phase 1
The purpose of this study is to evaluate the safety and tolerability of administering a
single intravenous (IV) infusion dose of TAK-925 to adults with obstructive sleep apnea (OSA)
who are experiencing excessive daytime sleepiness (EDS) despite adequate use of CPAP as the
primary OSA therapy.
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