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Last Updated: December 11, 2024

CLINICAL TRIALS PROFILE FOR TIPIFARNIB


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Clinical Trials for Tipifarnib

Trial ID Title Status Sponsor Phase Summary
NCT00003707 ↗ Combination Chemotherapy in Treating Patients With Advanced Cancer Completed National Cancer Institute (NCI) Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of combining R115777 with gemcitabine in treating patients with advanced cancer.
NCT00003707 ↗ Combination Chemotherapy in Treating Patients With Advanced Cancer Completed The University of Texas Health Science Center at San Antonio Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase I trial to study the effectiveness of combining R115777 with gemcitabine in treating patients with advanced cancer.
NCT00004009 ↗ R115777 in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia Completed National Cancer Institute (NCI) Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of R115777 in treating patients who have refractory or recurrent acute leukemia or chronic myelogenous leukemia.
NCT00004009 ↗ R115777 in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia Completed University of Maryland Greenebaum Cancer Center Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of R115777 in treating patients who have refractory or recurrent acute leukemia or chronic myelogenous leukemia.
NCT00004009 ↗ R115777 in Treating Patients With Refractory or Recurrent Acute Leukemia or Chronic Myelogenous Leukemia Completed University of Maryland, Baltimore Phase 1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of R115777 in treating patients who have refractory or recurrent acute leukemia or chronic myelogenous leukemia.
NCT00005041 ↗ R115777 in Treating Patients With Relapsed Small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of R115777 in treating patients who have relapsed small cell lung cancer.
NCT00005041 ↗ R115777 in Treating Patients With Relapsed Small Cell Lung Cancer Completed New York University School of Medicine Phase 2 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase II trial to study the effectiveness of R115777 in treating patients who have relapsed small cell lung cancer.
>Trial ID >Title >Status >Phase >Summary

Clinical Trial Conditions for Tipifarnib

Condition Name

Condition Name
Intervention Trials
Leukemia 8
Untreated Adult Acute Myeloid Leukemia 8
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22) 7
Adult Acute Myeloid Leukemia With t(8;21)(q22;q22) 7
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Condition MeSH

Condition MeSH
Intervention Trials
Leukemia 27
Leukemia, Myeloid 22
Leukemia, Myeloid, Acute 19
Leukemia, Myelomonocytic, Acute 13
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Clinical Trial Locations for Tipifarnib

Trials by Country

Trials by Country
Location Trials
United States 356
Spain 15
United Kingdom 8
Canada 6
Germany 6
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Trials by US State

Trials by US State
Location Trials
California 22
New York 22
Texas 22
Florida 18
Maryland 17
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Clinical Trial Progress for Tipifarnib

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase Trials
Phase 3 3
Phase 2/Phase 3 1
Phase 2 46
[disabled in preview] 35
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Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase Trials
Completed 68
Recruiting 8
Terminated 5
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Clinical Trial Sponsors for Tipifarnib

Sponsor Name

Sponsor Name
Sponsor Trials
National Cancer Institute (NCI) 63
Kura Oncology, Inc. 8
Johnson & Johnson Pharmaceutical Research & Development, L.L.C. 7
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Sponsor Type

Sponsor Type
Sponsor Trials
NIH 65
Other 39
Industry 21
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