Study to Assess the Effect of Multiple Doses of Tradipitant on CYP3A4 Using Midazolam as a Substrate in Healthy Subjects
Completed
Cross Research S.A.
Phase 1
This study is designed to evaluate the potential effect of administration of tradipitant on
CYP3A4 using midazolam pharmacokinetics as markers.
The study will also further characterize the pharmacokinetics of tradipitant.
Study to Assess the Effect of Multiple Doses of Tradipitant on CYP3A4 Using Midazolam as a Substrate in Healthy Subjects
Completed
Vanda Pharmaceuticals
Phase 1
This study is designed to evaluate the potential effect of administration of tradipitant on
CYP3A4 using midazolam pharmacokinetics as markers.
The study will also further characterize the pharmacokinetics of tradipitant.
Tradipitant in Treatment-resistant Pruritus Associated With Atopic Dermatitis
Completed
Vanda Pharmaceuticals
Phase 2
This is a multicenter, randomized, double-blind, placebo-controlled study to be conducted in
the United States in subjects with treatment-resistant pruritus diagnosed with atopic
dermatitis.
Study to Assess the Efficacy of VLY-686 in Relieving Symptoms of Gastroparesis
Unknown status
Vanda Pharmaceuticals
Phase 2
This is a multicenter, randomized, double-blind, placebo-controlled study to be conducted in
the United States. One hundred fifty (150) subjects diagnosed with gastroparesis, who satisfy
the selection criteria for the study, will be randomized to one of two treatment groups,
active or placebo.
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