CLINICAL TRIALS PROFILE FOR TREOSULFAN

Clinical Trials for Treosulfan

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00129155 ↗	MiniMUD Study - Unrelated Reduced Intensity Conditioning With Treosulfan® for Allogeneic Stem Cell Transplantation in Patients With Hematological Malignancies	Unknown status	Hospices Civils de Lyon	Phase 2	In this study, treosulfan is evaluated for conditioning in allogenic stem cell transplantation. The procedure and the follow-up are the same as in standard allogenic transplant. The donor is unrelated (identical HLA). The graft is haematological peripheral blood stem cell. The conditioning with reduced intensity is: fludarabine (from day -6 to day -2), treosulfan (from day -6 to day -4) and thymoglobuline (from day -2 to day -1).
NCT00168870 ↗	Study of Metastatic Ocular Melanoma	Unknown status	Charite University, Berlin, Germany	Phase 2	This study evaluates treatment with combination versus monotherapy for patients with metastatic ocular melanoma.
NCT00170690 ↗	Preference Study With Elderly Patients Recurrent Ovarian Cancer	Completed	North Eastern German Society of Gynaecological Oncology	Phase 3	Comparison of the patient compliance treosulfan oral vs. intravenous (defined as end of therapy for the patient)
NCT00170690 ↗	Preference Study With Elderly Patients Recurrent Ovarian Cancer	Completed	North Eastern Germany Society of Gynaecologic Oncology	Phase 3	Comparison of the patient compliance treosulfan oral vs. intravenous (defined as end of therapy for the patient)

Clinical Trial Conditions for Treosulfan

Condition Name

Condition Name
Intervention	Trials
Myelodysplastic Syndrome	8
Acute Myeloid Leukemia	5
Chronic Myelomonocytic Leukemia	5
Multiple Myeloma	4

Condition MeSH

Condition MeSH
Intervention	Trials
Myelodysplastic Syndromes	16
Leukemia	16
Preleukemia	14
Leukemia, Myeloid, Acute	13

Clinical Trial Locations for Treosulfan

Trials by Country

Trials by Country
Location	Trials
United States	54
Germany	21
Italy	12
Poland	6
Canada	6

Trials by US State

Trials by US State
Location	Trials
Washington	10
Oregon	6
Colorado	5
Wisconsin	4
Tennessee	3

Clinical Trial Progress for Treosulfan

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	8
Phase 2/Phase 3	1
Phase 2	29

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	14
Unknown status	11
Recruiting	7

Clinical Trial Sponsors for Treosulfan

Sponsor Name

Sponsor Name
Sponsor	Trials
medac GmbH	14
Fred Hutchinson Cancer Research Center	8
National Cancer Institute (NCI)	8

Sponsor Type

Sponsor Type
Sponsor	Trials
Other	62
Industry	26
NIH	12