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Last Updated: December 26, 2024

CLINICAL TRIALS PROFILE FOR TRIAPINE

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Clinical Trials for Triapine

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00004213 ↗	3-Aminopyridine-2-carboxaldehyde Thiosemicarbazone in Treating Patients With Solid Tumors	Completed	Vion Pharmaceuticals	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone in treating patients who have solid tumors that have not responded to previous treatment.
NCT00006218 ↗	3-AP in Treating Patients With Advanced Cancer	Completed	Vion Pharmaceuticals	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of 3-AP in treating patients who have advanced cancer.
NCT00016874 ↗	3-AP Plus Cisplatin and Paclitaxel in Treating Patients With Advanced or Metastatic Cancer	Completed	Vion Pharmaceuticals	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combining 3-AP, cisplatin, and paclitaxel in treating patients who have advanced or metastatic cancer.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Triapine

Condition Name

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Condition Name
Intervention	Trials
Unspecified Adult Solid Tumor, Protocol Specific	8
Stage IVA Cervical Cancer	5
Stage IVA Vaginal Cancer	4
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Condition MeSH

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Condition MeSH
Intervention	Trials
Adenocarcinoma	7
Leukemia	5
Vaginal Neoplasms	5
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Clinical Trial Locations for Triapine

Trials by Country

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Trials by Country
Location	Trials
United States	141
Canada	6
Puerto Rico	2
Australia	2
United Kingdom	1
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Trials by US State

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Trials by US State
Location	Trials
Ohio	7
Minnesota	7
Illinois	7
Pennsylvania	6
California	6
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Clinical Trial Progress for Triapine

Clinical Trial Phase

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Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	15
Phase 1	15
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Clinical Trial Status

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Clinical Trial Status
Clinical Trial Phase	Trials
Completed	26
Recruiting	5
Terminated	1
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Clinical Trial Sponsors for Triapine

Sponsor Name

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Sponsor Name
Sponsor	Trials
National Cancer Institute (NCI)	25
Vion Pharmaceuticals	8
NRG Oncology	2
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Sponsor Type

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Sponsor Type
Sponsor	Trials
NIH	25
Industry	8
Other	7
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