CLINICAL TRIALS PROFILE FOR VARESPLADIB METHYL

Clinical Trials for Varespladib methyl

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00743925 ↗	FRANCIS-ACS Trial: A Study of the Safety and Efficacy of A 002 in Subjects With Acute Coronary Syndromes	Completed	Anthera Pharmaceuticals	Phase 2	The objective of this study is to evaluate the safety and efficacy of A 002 when added to high dose atorvastatin in subjects with an acute coronary syndrome (ACS)
NCT01130246 ↗	VISTA-16 Trial: Evaluation of Safety and Efficacy of Short-term A-002 Treatment in Subjects With Acute Coronary Syndrome	Terminated	Anthera Pharmaceuticals	Phase 3	The objective of this study is to evaluate the safety and efficacy of short-term A-002 treatment on morbidity and mortality when added to atorvastatin and standard of care in subjects with an acute coronary syndrome (ACS).
NCT01359579 ↗	A Study of the Pharmacokinetics and Safety of Varespladib in Subjects With Normal or Impaired Renal Function	Terminated	Anthera Pharmaceuticals	Phase 1	The purpose of this study is to compare and evaluate the pharmacokinetic characteristics and the safety of varespladib methyl in mild or moderate renal impairment patients and healthy volunteers.
NCT01359605 ↗	Study to Assess the Metabolism and Elimination of [14C]-Labeled Varespladib Methyl in Healthy Male Subjects	Completed	Anthera Pharmaceuticals	Phase 1	The purpose of the study is to characterize the metabolism and excretion (ADME) of a single oral dose of [14C]varespladib methyl.

Clinical Trial Conditions for Varespladib methyl

Condition Name

Condition Name
Intervention	Trials
Acute Coronary Syndrome	2
Envenomation, Snake	1
Envenoming	1
Envenoming, Snake	1

Condition MeSH

Condition MeSH
Intervention	Trials
Acute Coronary Syndrome	2
Syndrome	2
Snake Bites	1
Renal Insufficiency	1

Clinical Trial Locations for Varespladib methyl

Trials by Country

Trials by Country
Location	Trials
United States	39
Hungary	9
India	9
Spain	8
Australia	8

Trials by US State

Trials by US State
Location	Trials
North Carolina	2
Nebraska	2
Minnesota	2
Florida	2
California	2

Clinical Trial Progress for Varespladib methyl

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 3	1
Phase 2	2
Phase 1	2

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	2
Terminated	2
Recruiting	1

Clinical Trial Sponsors for Varespladib methyl

Sponsor Name

Sponsor Name
Sponsor	Trials
Anthera Pharmaceuticals	4
Premier Research International LLC	1
Ophirex, Inc.	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	5
Other	1