CLINICAL TRIALS PROFILE FOR DANICAMTIV

Clinical Trials for danicamtiv

Trial ID	Title	Status	Sponsor	Phase	Summary
NCT04572893 ↗	Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants	Recruiting	MyoKardia, Inc.	Phase 2	The purpose of this Phase 2a study is to establish safety and preliminary efficacy of treatment with danicamtiv in patients with primary dilated cardiomyopathy (DCM) due to MYH7 or TTN variants .
NCT05162222 ↗	A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Single-dose of Danicamtiv in Healthy Participants	Not yet recruiting	Bristol-Myers Squibb	Phase 1	The purpose of this study is to evaluate the effects of co-administration of itraconazole or diltiazem on the single-dose pharmacokinetics of danicamtiv in healthy participants.
NCT05806359 ↗	A Study to Evaluate the Safety, Tolerability, and Drug Levels of Danicamtiv in Healthy Japanese and Caucasian Participants	Not yet recruiting	Bristol-Myers Squibb	Phase 1	The purpose of this study is to assess the safety, tolerability, and single-dose pharmacokinetics of danicamtiv in healthy Japanese and Caucasian participants.
NCT05952089 ↗	A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failure	Completed	Bristol-Myers Squibb	Phase 1	The purpose of this study is assess the effect of danicamtiv, as an inducer on the drug levels of midazolam in participants with heart failure with reduced ejection fraction (HFrEF).

Clinical Trial Conditions for danicamtiv

Condition Name

Condition Name
Intervention	Trials
Healthy Volunteers	2
Healthy Participants	1
Heart Failure With Reduced Ejection Fraction	1
Primary Familial Dilated Cardiomyopathy	1

Condition MeSH

Condition MeSH
Intervention	Trials
Heart Failure	1
Cardiomyopathy, Dilated	1
Cardiomyopathies	1

Clinical Trial Locations for danicamtiv

Trials by Country

Trials by Country
Location	Trials
United States	17
Spain	3
Germany	1
United Kingdom	1

Trials by US State

Trials by US State
Location	Trials
California	3
Texas	2
Florida	2
Kentucky	1
Tennessee	1

Clinical Trial Progress for danicamtiv

Clinical Trial Phase

Clinical Trial Phase
Clinical Trial Phase	Trials
Phase 2	1
Phase 1	4

Clinical Trial Status

Clinical Trial Status
Clinical Trial Phase	Trials
Completed	2
Not yet recruiting	2
Recruiting	1

Clinical Trial Sponsors for danicamtiv

Sponsor Name

Sponsor Name
Sponsor	Trials
Bristol-Myers Squibb	4
MyoKardia, Inc.	1

Sponsor Type

Sponsor Type
Sponsor	Trials
Industry	5