Exploratory Study of Danicamtiv in Patients With Primary Dilated Cardiomyopathy (DCM) Due to Genetic Variants
Recruiting
MyoKardia, Inc.
Phase 2
The purpose of this Phase 2a study is to establish safety and preliminary efficacy of
treatment with danicamtiv in patients with primary dilated cardiomyopathy (DCM) due to MYH7
or TTN variants .
A Study to Evaluate the Effect of Co-administration of Itraconazole or Diltiazem on the Single-dose of Danicamtiv in Healthy Participants
Not yet recruiting
Bristol-Myers Squibb
Phase 1
The purpose of this study is to evaluate the effects of co-administration of itraconazole or
diltiazem on the single-dose pharmacokinetics of danicamtiv in healthy participants.
A Study to Evaluate the Safety, Tolerability, and Drug Levels of Danicamtiv in Healthy Japanese and Caucasian Participants
Not yet recruiting
Bristol-Myers Squibb
Phase 1
The purpose of this study is to assess the safety, tolerability, and single-dose
pharmacokinetics of danicamtiv in healthy Japanese and Caucasian participants.
A Study to Assess the Effect of Danicamtiv on the Drug Levels of Midazolam in Participants With Stable Heart Failure
Completed
Bristol-Myers Squibb
Phase 1
The purpose of this study is assess the effect of danicamtiv, as an inducer on the drug
levels of midazolam in participants with heart failure with reduced ejection fraction
(HFrEF).
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