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Last Updated: December 22, 2024

ALTRETAMINE - Generic Drug Details


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What are the generic sources for altretamine and what is the scope of patent protection?

Altretamine is the generic ingredient in one branded drug marketed by Eisai Inc and is included in one NDA. Additional information is available in the individual branded drug profile pages.

There is one drug master file entry for altretamine.

Summary for ALTRETAMINE
Recent Clinical Trials for ALTRETAMINE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Roswell Park Cancer InstitutePhase 1
National Cancer Institute (NCI)Phase 1

See all ALTRETAMINE clinical trials

Medical Subject Heading (MeSH) Categories for ALTRETAMINE

US Patents and Regulatory Information for ALTRETAMINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Eisai Inc HEXALEN altretamine CAPSULE;ORAL 019926-001 Dec 26, 1990 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

ALTRETAMINE Market Analysis and Financial Projection Experimental

Altretamine Market Dynamics and Financial Trajectory

Market Overview

Altretamine, known by its trade name Hexalen, is an orally administered alkylating agent used primarily in the treatment of advanced ovarian carcinoma. The drug has been associated with low rates of serum enzyme elevations and rare instances of acute, clinically apparent injury[1][3][4].

Market Growth Drivers

The Altretamine market is anticipated to experience significant growth driven by several key factors:

Increasing Prevalence of Cancers

The global rise in cancer incidence, particularly ovarian cancer, is a major driver for the Altretamine market. Ovarian cancer is one of the leading causes of cancer-related deaths among women, and Altretamine is often used as a secondary therapy for advanced cases[1][4].

Government Initiatives and Awareness

Government initiatives aimed at improving cancer treatment and awareness are propelling the market growth. These initiatives include funding for research, public health campaigns, and policies that support the development and accessibility of cancer treatments[1][5].

Technological Advancements

Advancements in medical technology and pharmaceutical research are enhancing the efficacy and safety of Altretamine. This includes the development of combination therapies and the exploration of Altretamine's potential in treating other types of cancer[3][4].

Market Segmentation

The Altretamine market is segmented based on several criteria:

By Type

The market is segmented into capsules, tablets, and enteric-coated tablets. Each form has its own set of advantages and is used based on patient needs and treatment protocols[1].

By Application

The market is segmented into hospital pharmacies, retail pharmacies, and online pharmacies. This segmentation reflects the various channels through which Altretamine is distributed and accessed by patients[1].

By Region

The global Altretamine market is analyzed across five major regions: North America, Europe, Asia-Pacific (APAC), Middle East and Africa (MEA), and South & Central America. Each region has its own market dynamics influenced by local healthcare infrastructure, regulatory environments, and prevalence of ovarian cancer[1][4].

Regional Analysis

North America

North America leads the Altretamine market due to high healthcare expenditure, advanced medical infrastructure, and early adoption of novel cancer therapies. The region is home to many key pharmaceutical companies and research institutions that drive innovation in cancer treatment[4].

Europe

Europe follows closely, driven by supportive healthcare policies and a strong emphasis on research and development in oncology. European countries have robust healthcare systems that facilitate the adoption of new cancer treatments[4].

Asia Pacific

The Asia Pacific region represents a rapidly growing market, propelled by increasing incidences of ovarian cancer and improving access to healthcare in countries like China and India. This region is expected to contribute significantly to the global market growth due to its large population and growing healthcare infrastructure[4].

Competitive Landscape

The Altretamine market is moderately fragmented with several key players:

Major Players

Companies such as ACTIZA, NATCO PHARMA, EISAI, DR. REDDY'S, and MGI PHARMA, INC are prominent in the market. These companies have extensive product portfolios and global distribution networks that enable them to dominate the market[1][4].

Strategic Initiatives

Market players are focusing on strategic collaborations, acquisitions, and product innovations to strengthen their market position and expand their footprint in emerging markets. These initiatives include partnerships for research and development, investments in production facilities, and expansion of distribution networks[1][4].

Financial Trajectory

Market Size and Growth

The global Altretamine market is expected to witness high growth during the forecast period from 2024 to 2031. The market size is projected to increase significantly, driven by the increasing incidence of cancers and the growing demand for effective treatment options[1][4].

Revenue Forecast

The revenue forecast for the Altretamine market indicates a steady increase, with the market expected to reach a substantial value by 2031. This growth is supported by historical data and current trends in the pharmaceutical industry[1][4].

Cost and Pricing

The cost of Altretamine can vary based on the region, distribution channel, and form of the drug. However, the overall cost-effectiveness of the drug, especially when used in combination therapies, is a significant factor in its market growth. The drug offers a reasonably well-tolerated regimen that can be administered orally, reducing the need for hospital visits and associated costs[3][4].

Market Opportunities and Challenges

Market Opportunities

An emerging opportunity lies in expanding the application of Altretamine beyond ovarian cancer. Clinical trials and research are exploring its efficacy in other cancer types, such as lung and colorectal cancers, which could significantly broaden its market scope. Strategic partnerships and collaborations for research and development could accelerate the drug's availability and adoption in untapped markets[4].

Market Challenges

Despite its efficacy, the Altretamine market faces challenges such as stringent regulatory approvals and the emergence of alternative therapies. Regulatory hurdles in different regions can delay market entry and limit availability, affecting patient access. Additionally, the availability of alternative treatments and therapies, including targeted therapies and immunotherapies, poses a competitive challenge to Altretamine[4].

Key Takeaways

  • Growing Incidence of Ovarian Cancer: The primary market for Altretamine revolves around ovarian cancer treatment, driven by the increasing incidence of this disease.
  • Advancements in Combination Therapies: Researchers are increasingly exploring Altretamine in combination with other drugs to enhance treatment outcomes and reduce side effects.
  • Emerging Markets: Developing regions are becoming significant contributors to market growth due to improving healthcare infrastructure and rising awareness about cancer treatments.
  • Regulatory and Competitive Challenges: The market faces challenges from stringent regulatory approvals and the emergence of alternative therapies.

FAQs

Q: What is Altretamine used for? Altretamine is primarily used in the treatment of advanced ovarian carcinoma, particularly in patients who have not responded to primary therapies.

Q: What are the main drivers of the Altretamine market? The main drivers include the increasing prevalence of cancers, government initiatives for treatment and awareness, and technological advancements in therapy.

Q: Which regions are leading the Altretamine market? North America and Europe are currently leading the market, with the Asia Pacific region showing rapid growth.

Q: What are the main challenges facing the Altretamine market? The market faces challenges from stringent regulatory approvals and the emergence of alternative therapies such as targeted therapies and immunotherapies.

Q: What are the potential future applications of Altretamine? Clinical trials and research are exploring Altretamine's efficacy in other cancer types, such as lung and colorectal cancers, which could broaden its market scope.

Sources

  1. The Insight Partners, "Altretamine Market Size and Forecasts (2021 - 2031), Global and Regional Analysis".
  2. CMS, "Evaluation of the Medicare Replacement Drug Demonstration".
  3. PubMed, "Altretamine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in cancer chemotherapy".
  4. DataHorizon Research, "Altretamine Market Size, Growth and Analysis Report - 2033".
  5. LSE, "The role of funding and policies on innovation in cancer drug development".

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