ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE - Generic Drug Details

What are the generic drug sources for aspirin; caffeine; orphenadrine citrate and what is the scope of patent protection?

Aspirin; caffeine; orphenadrine citrate is the generic ingredient in seven branded drugs marketed by Sandoz, Bausch, Stevens J, and Galt Pharms, and is included in five NDAs. Additional information is available in the individual branded drug profile pages.

Three suppliers are listed for this compound.

Summary for ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE

US Patents:	0
Tradenames:	7
Applicants:	4
NDAs:	5
Finished Product Suppliers / Packagers:	3
DailyMed Link:	ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE at DailyMed

Pharmacology for ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE

Drug Class	Central Nervous System Stimulant Methylxanthine Muscle Relaxant Nonsteroidal Anti-inflammatory Drug Platelet Aggregation Inhibitor
Mechanism of Action	Cyclooxygenase Inhibitors
Physiological Effect	Central Nervous System Stimulation Centrally-mediated Muscle Relaxation Decreased Platelet Aggregation Decreased Prostaglandin Production

Anatomical Therapeutic Chemical (ATC) Classes for ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE

D11AX	Other dermatologicals
D11A	OTHER DERMATOLOGICAL PREPARATIONS
D11	OTHER DERMATOLOGICAL PREPARATIONS
D	Dermatologicals

N06BC	Xanthine derivatives
N06B	PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
N06	PSYCHOANALEPTICS
N	Nervous system

US Patents and Regulatory Information for ASPIRIN; CAFFEINE; ORPHENADRINE CITRATE

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Stevens J	ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	074988-001	Apr 30, 1999		DISCN	No	No
Sandoz	INVAGESIC	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	074817-001	Nov 27, 1996		DISCN	No	No
Sandoz	ORPHENADRINE CITRATE, ASPIRIN, AND CAFFEINE	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	074654-001	Dec 31, 1996		DISCN	No	No
Bausch	NORGESIC FORTE	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	013416-004	Oct 27, 1982		DISCN	Yes	No
Galt Pharms	ORPHENGESIC	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	075141-001	May 29, 1998		RX	No	No
Bausch	NORGESIC	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	013416-003	Oct 27, 1982		DISCN	Yes	No
Galt Pharms	ORPHENGESIC FORTE	aspirin; caffeine; orphenadrine citrate	TABLET;ORAL	075141-002	May 29, 1998		RX	No	Yes