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Last Updated: December 22, 2024

CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE - Generic Drug Details


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What are the generic drug sources for chlorthalidone; clonidine hydrochloride and what is the scope of freedom to operate?

Chlorthalidone; clonidine hydrochloride is the generic ingredient in three branded drugs marketed by Par Pharm, Natco Pharma, and Boehringer Ingelheim, and is included in five NDAs. Additional information is available in the individual branded drug profile pages.

Summary for CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE
US Patents:0
Tradenames:3
Applicants:3
NDAs:5
Clinical Trials: 2
DailyMed Link:CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE at DailyMed
Recent Clinical Trials for CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
Instituto do CoracaoPhase 4
Conselho Nacional de Desenvolvimento Científico e TecnológicoPhase 4
VA Office of Research and Development

See all CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE clinical trials

US Patents and Regulatory Information for CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Natco Pharma CLORPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 071325-003 Feb 9, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Natco Pharma CLORPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 071325-002 Feb 9, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Par Pharm CLONIDINE HYDROCHLORIDE AND CHLORTHALIDONE chlorthalidone; clonidine hydrochloride TABLET;ORAL 071179-001 Dec 16, 1987 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Boehringer Ingelheim COMBIPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 017503-001 Approved Prior to Jan 1, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Boehringer Ingelheim COMBIPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 017503-003 Apr 10, 1984 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

Expired US Patents for CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date Patent No. Patent Expiration
Boehringer Ingelheim COMBIPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 017503-001 Approved Prior to Jan 1, 1982 ⤷  Subscribe ⤷  Subscribe
Boehringer Ingelheim COMBIPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 017503-003 Apr 10, 1984 ⤷  Subscribe ⤷  Subscribe
Boehringer Ingelheim COMBIPRES chlorthalidone; clonidine hydrochloride TABLET;ORAL 017503-002 Approved Prior to Jan 1, 1982 ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >Patent No. >Patent Expiration

CHLORTHALIDONE; CLONIDINE HYDROCHLORIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Chlorthalidone and Clonidine Hydrochloride

Introduction to Chlorthalidone and Clonidine Hydrochloride

Chlorthalidone and clonidine hydrochloride are two significant pharmaceuticals used in the treatment of various medical conditions. Chlorthalidone is a diuretic used primarily for hypertension and edema, while clonidine hydrochloride is utilized for hypertension, hypertensive emergencies, and other conditions like migraine.

Chlorthalidone Market Dynamics

Market Position and Indications

Chlorthalidone is a well-established diuretic, often prescribed for the treatment of hypertension and edema. Its market position is influenced by its long-standing presence and efficacy in managing these conditions[3].

Financial Trajectory

The financial trajectory of chlorthalidone is characterized by stable demand due to its generic status. Since the patents for chlorthalidone have expired, the market is open to multiple generic manufacturers, which has led to competitive pricing and a steady revenue stream. The generic market for chlorthalidone is less volatile compared to branded drugs, as it is less affected by patent expirations and litigation.

Market Challenges

Despite its stable demand, the chlorthalidone market faces challenges such as competition from newer diuretics and other antihypertensive drugs. Additionally, regulatory changes and pricing pressures can impact the profitability of generic manufacturers[3].

Regional Analysis

The market for chlorthalidone is global, with significant demand in regions where hypertension is a prevalent health issue. North America, Europe, and Asia-Pacific are key markets, driven by large patient populations and established healthcare systems.

Clonidine Hydrochloride Market Dynamics

Market Size and Growth

The clonidine hydrochloride market has experienced rapid growth in recent years and is projected to continue this trend from 2023 to 2031. The market size is expected to expand significantly, driven by increasing demand for hypertension and other treatments[5].

Application Segments

Clonidine hydrochloride is used in various applications, including hypertension, hypertensive emergencies, and migraine. The hypertension segment is the largest, driving a substantial portion of the market's revenue. Other applications, such as migraine treatment, also contribute to the market's growth[5].

Regional Analysis

The clonidine hydrochloride market is segmented geographically into North America, Europe, Asia-Pacific, South America, and the Middle East and Africa. North America and Europe are significant markets due to high healthcare spending and a large patient base. Asia-Pacific, particularly countries like China and India, is also experiencing robust growth due to increasing healthcare awareness and infrastructure development[5].

Market Dynamics

The market dynamics for clonidine hydrochloride are influenced by several factors:

  • Drivers: Increasing prevalence of hypertension, growing healthcare expenditure, and expanding awareness of treatment options.
  • Restraints: Competition from alternative treatments, regulatory challenges, and pricing pressures.
  • Opportunities: Emerging markets in Asia-Pacific and Latin America, and the potential for new applications.
  • Challenges: Patent expirations and the entry of generic competitors, which can impact market share and revenue[5].

Financial Trajectory

The financial trajectory of clonidine hydrochloride is marked by strong growth projections. The market is expected to expand significantly, with a robust CAGR from 2023 to 2031. This growth is driven by increasing demand, expanding applications, and favorable market dynamics.

Comparative Analysis

Market Size

The clonidine hydrochloride market is larger and more dynamic compared to the chlorthalidone market. While chlorthalidone has a stable but relatively smaller market size due to its generic status, clonidine hydrochloride is experiencing rapid expansion driven by its multiple applications and growing demand[5].

Growth Rate

Clonidine hydrochloride has a higher growth rate compared to chlorthalidone. The clonidine hydrochloride market is projected to grow significantly over the next several years, whereas the chlorthalidone market, while stable, does not exhibit the same level of growth[5].

Competitive Landscape

The competitive landscape for clonidine hydrochloride is more complex due to the presence of both branded and generic players. Chlorthalidone, being a generic drug, has a more straightforward competitive landscape with multiple generic manufacturers competing on price and quality[3].

Key Takeaways

  • Chlorthalidone: Stable demand, generic status, and competitive pricing characterize the market. Despite challenges, it remains a significant player in the diuretic market.
  • Clonidine Hydrochloride: Rapid growth, multiple applications, and a strong financial trajectory define this market. It is poised for significant expansion driven by increasing demand and favorable market dynamics.
  • Regional Analysis: Both markets have global reach, but clonidine hydrochloride shows more robust growth in emerging markets.
  • Market Dynamics: Clonidine hydrochloride faces more dynamic market conditions with higher growth potential, while chlorthalidone's market is more stable.

FAQs

What are the primary indications for chlorthalidone and clonidine hydrochloride?

  • Chlorthalidone: Primarily used for hypertension and edema.
  • Clonidine Hydrochloride: Used for hypertension, hypertensive emergencies, and migraine.

What is the expected growth rate for the clonidine hydrochloride market?

The clonidine hydrochloride market is projected to experience significant growth from 2023 to 2031, with robust growth rates during the forecasted period[5].

How does the competitive landscape differ between chlorthalidone and clonidine hydrochloride?

  • Chlorthalidone: Characterized by multiple generic manufacturers competing on price and quality.
  • Clonidine Hydrochloride: Involves both branded and generic players, with a more complex competitive landscape[3][5].

What are the key drivers for the clonidine hydrochloride market?

Key drivers include increasing prevalence of hypertension, growing healthcare expenditure, and expanding awareness of treatment options[5].

How does the regional analysis compare between the two drugs?

Both markets have global reach, but clonidine hydrochloride shows more robust growth in emerging markets such as Asia-Pacific and Latin America[5].

Sources

  1. Azilsartan Medoxomil API Market Growth Insights 2024: Market Research Guru.
  2. Global Clonidine Hydrochloride Market Size, Scope And Forecast Report: Market Research Intellect.
  3. Generic CHLORTHALIDONE INN entry, pharmaceutical patent: Drug Patent Watch.
  4. When do the patents on EDARBYCLOR expire, and when will generic versions be available?: Drug Patent Watch.
  5. Global Clonidine Hydrochloride Market Size, Trends and Projections: Market Research Intellect.

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