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Last Updated: December 22, 2024

GRISEOFULVIN, ULTRAMICROCRYSTALLINE - Generic Drug Details


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What are the generic sources for griseofulvin, ultramicrocrystalline and what is the scope of patent protection?

Griseofulvin, ultramicrocrystalline is the generic ingredient in three branded drugs marketed by Wyeth Ayerst and Pliva, and is included in four NDAs. Additional information is available in the individual branded drug profile pages.

Summary for GRISEOFULVIN, ULTRAMICROCRYSTALLINE

US Patents and Regulatory Information for GRISEOFULVIN, ULTRAMICROCRYSTALLINE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Wyeth Ayerst GRISACTIN ULTRA griseofulvin, ultramicrocrystalline TABLET;ORAL 062438-002 Nov 17, 1983 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pliva ULTRAGRIS-165 griseofulvin, ultramicrocrystalline TABLET;ORAL 062645-001 Jun 30, 1992 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Wyeth Ayerst GRISACTIN ULTRA griseofulvin, ultramicrocrystalline TABLET;ORAL 062178-001 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Wyeth Ayerst GRISACTIN ULTRA griseofulvin, ultramicrocrystalline TABLET;ORAL 062178-002 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Pliva ULTRAGRIS-330 griseofulvin, ultramicrocrystalline TABLET;ORAL 062646-001 Jun 30, 1992 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

GRISEOFULVIN, ULTRAMICROCRYSTALLINE Market Analysis and Financial Projection Experimental

Griseofulvin Market Dynamics and Financial Trajectory

Introduction to Griseofulvin

Griseofulvin is an antifungal medication derived from species of the fungus Penicillium, specifically used to treat various types of ringworm infections, including tinea corporis, tinea pedis, tinea cruris, tinea capitis, and tinea unguium. Here, we delve into the market dynamics and financial trajectory of griseofulvin, particularly its ultramicrocrystalline form.

Market Size and Growth

The global griseofulvin market is anticipated to experience significant growth over the forecast period from 2024 to 2031. The market size in 2023 was substantial, and the compound annual growth rate (CAGR) is expected to be robust during the forecast period[1][3].

Key Drivers

Several factors are driving the growth of the griseofulvin market:

Increase in Fungal Infections

The rise in cases of dermatophytosis, particularly post-COVID-19, is a significant driver. The pandemic has led to an increased susceptibility to fungal infections due to weakened immune systems[3].

Geriatric Population

The globally rising geriatric population contributes to the high prevalence of dermatophytosis, as the immune system weakens with age[3].

Lifestyle Factors

A sedentary lifestyle and the increase in hospital-acquired diseases have also contributed to the higher rate of dermatophytosis, boosting the demand for griseofulvin[3].

Market Segmentation

The griseofulvin market is segmented based on type, application, and region.

By Type

The market includes segments such as Penicillium Nigrum, Penicillium Urticae, and other types. The Penicillium Nigrum segment accounted for a noticeable share of the global market and is projected to experience significant growth[1].

By Application

Griseofulvin is used in agriculture, medicine, the chemical industry, and other applications. The agriculture segment is expected to expand at a significant CAGR throughout the forecast period[1].

By Region

The market is segmented into North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America. Each region provides a detailed analysis of revenue share, current trends, and future prospects[1].

Competitive Landscape

The griseofulvin market is competitive, with several key players:

  • GlaxoSmithKline
  • Dr. Reddy's Laboratories
  • CFL Pharmaceuticals Limited
  • Chifeng Pharmaceutical Co. Ltd
  • Inga Pharmaceuticals
  • Nippon Kayaku
  • BAL Pharma Ltd
  • Comed Chemicals Limited

These companies are focusing on strategy building and expanding their product portfolios to strengthen their market positions[1][3].

Financial Trajectory

Revenue Growth

The global griseofulvin market is expected to witness significant revenue growth. The forecast period from 2025 to 2031 indicates a robust CAGR, driven by the increasing demand for antifungal treatments[1][3].

Regional Analysis

Regional analysis shows that each major region, including North America, Europe, Asia-Pacific, Middle East & Africa, and Latin America, will contribute to the overall revenue growth. The report provides detailed figures, graphs, and tables to explain the data analysis at the country and regional levels[1].

Challenges and Restraints

Despite the growth prospects, the griseofulvin market faces several challenges:

Limited Spectrum of Activity

Griseofulvin functions as a fungistatic agent rather than a fungicidal agent, which makes it less competitive against newer drugs like terbinafine and itraconazole. It has a limited spectrum of activity and is only effective against dermatophyte-related onychomycosis[3].

Lack of Awareness

The lack of awareness about dermatophytosis and related fungal diseases, as well as treatment options, limits the growth prospects of the market. Additionally, patient reluctance to receive fungal infection treatment further hampers market growth[3].

Technological and Pharmaceutical Trends

Ultramicrocrystalline Form

The ultramicrocrystalline form of griseofulvin has higher gastrointestinal absorption efficiency compared to the conventional microsize form. This allows for lower doses while maintaining efficacy, although there is no significant clinical difference in safety and efficacy[2][4].

R&D Investments

Investments in the R&D sector are crucial for discovering new potential activities of griseofulvin. This could lead to new applications and improved formulations, further boosting market growth[3].

COVID-19 Impact

The COVID-19 pandemic has had a significant impact on the griseofulvin market. The increased susceptibility to fungal infections among patients who have recovered from COVID-19 is driving the demand for antifungal treatments. This trend is expected to continue in the upcoming years, contributing to the market's growth[3].

Key Takeaways

  • The global griseofulvin market is expected to grow significantly due to an increase in fungal infections and a rising geriatric population.
  • The ultramicrocrystalline form of griseofulvin offers higher absorption efficiency.
  • Key players are focusing on expanding their product portfolios and market presence.
  • Challenges include limited spectrum of activity and lack of awareness about fungal diseases.
  • R&D investments are crucial for market growth.

FAQs

Q: What are the primary applications of griseofulvin? A: Griseofulvin is primarily used in the treatment of various ringworm infections, including tinea corporis, tinea pedis, tinea cruris, tinea capitis, and tinea unguium. It is also used in agriculture and the chemical industry[1][2].

Q: Which segment of the griseofulvin market is expected to grow the most? A: The agriculture segment is expected to expand at a significant CAGR throughout the forecast period[1].

Q: How does the ultramicrocrystalline form of griseofulvin differ from the conventional microsize form? A: The ultramicrocrystalline form has higher gastrointestinal absorption efficiency, allowing for lower doses while maintaining efficacy[2][4].

Q: What are the major challenges facing the griseofulvin market? A: The major challenges include its limited spectrum of activity, lack of awareness about fungal diseases, and patient reluctance to receive treatment[3].

Q: How has the COVID-19 pandemic impacted the griseofulvin market? A: The pandemic has increased the susceptibility to fungal infections among recovered patients, driving the demand for antifungal treatments like griseofulvin[3].

Sources:

  1. Cognitivemarketresearch.com: Global Griseofulvin Market Report 2024 Edition.
  2. Accessdata.fda.gov: Gris-PEGĀ® (griseofulvin ultramicrosize) tablets, USP.
  3. Alliedmarketresearch.com: Griseofulvin Market Size & Growth | Analysis & Forecast 2030.
  4. IARC Publications: Griseofulvin 1. Exposure Data.

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