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Last Updated: December 22, 2024

HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE - Generic Drug Details


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What are the generic drug sources for hydrochlorothiazide; metoprolol succinate and what is the scope of patent protection?

Hydrochlorothiazide; metoprolol succinate is the generic ingredient in one branded drug marketed by Concordia and is included in one NDA. Additional information is available in the individual branded drug profile pages.

Summary for HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE
US Patents:0
Tradenames:1
Applicants:1
NDAs:1
Clinical Trials: 1
DailyMed Link:HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE at DailyMed
Recent Clinical Trials for HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE

Identify potential brand extensions & 505(b)(2) entrants

SponsorPhase
AstraZenecaPhase 3

See all HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE clinical trials

US Patents and Regulatory Information for HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Concordia DUTOPROL hydrochlorothiazide; metoprolol succinate TABLET, EXTENDED RELEASE;ORAL 021956-001 Aug 28, 2006 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Concordia DUTOPROL hydrochlorothiazide; metoprolol succinate TABLET, EXTENDED RELEASE;ORAL 021956-003 Aug 28, 2006 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Concordia DUTOPROL hydrochlorothiazide; metoprolol succinate TABLET, EXTENDED RELEASE;ORAL 021956-002 Aug 28, 2006 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

HYDROCHLOROTHIAZIDE; METOPROLOL SUCCINATE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Hydrochlorothiazide and Metoprolol Succinate

Introduction to Hydrochlorothiazide and Metoprolol Succinate

Hydrochlorothiazide and metoprolol succinate are two widely used medications in the treatment of hypertension and other cardiovascular conditions. Understanding their market dynamics and financial trajectories is crucial for pharmaceutical companies, investors, and healthcare professionals.

Hydrochlorothiazide Market Overview

Hydrochlorothiazide, a thiazide diuretic, is commonly used to treat hypertension and edema. Here are some key points about its market:

Market Size and Growth

The hydrochlorothiazide market is driven by the increasing prevalence of hypertension globally. It is estimated that 1.13 billion people suffer from hypertension, and this number is expected to rise to 29% by 2025, particularly in economically developing nations[3].

Key Drivers

  • Increasing Prevalence of Hypertension: The rising number of patients with hypertension is a significant driver for the hydrochlorothiazide market.
  • Geriatric Population: The growing geriatric population, which is more prone to hypertension, also boosts market growth.
  • FDA Approvals and New Drug Launches: Increased FDA approvals and the launch of novel drugs contribute to market expansion[3].

Market Trends

  • New Product Launches: Pharmaceutical companies are continuously developing new formulations and combinations, such as fixed-dose combinations like Losartan & Hydrochlorothiazide (Cozaar, Hyzaar), which enhance market growth[4].
  • Research and Development: Increased R&D activities and healthcare expenditure further propel the market.

Challenges

  • Side Effects: Side effects associated with hydrochlorothiazide, such as electrolyte imbalance and increased risk of diabetes, are expected to hamper market growth[3].

Metoprolol Succinate Market Overview

Metoprolol succinate, a beta-blocker, is used to treat hypertension, angina, and certain heart conditions. Here are the key points about its market:

Market Size and Growth

The metoprolol tartrate market, which includes metoprolol succinate, is projected to reach $868.3 million by 2027, growing at a CAGR of 5.2% during the forecast period 2022-2027[1].

Key Drivers

  • Increasing Prevalence of Heart Diseases: The rising prevalence of heart diseases, such as hypertension and myocardial infarction, drives the demand for metoprolol succinate.
  • Early Stage Heart Attack Treatment: The use of metoprolol tartrate injection in the early stages of heart attacks to minimize mortality rates further fuels market growth[1].

Geographical Analysis

  • North America: This region holds the largest market share due to the high prevalence of heart diseases. However, the Asia-Pacific region is expected to grow at the fastest CAGR due to the expanding application of metoprolol succinate in treating hypertension and angina[1].

Market Segmentation

  • Application: The market is segmented by application, including hypertension, myocardial infarction, angina pectoris, and other conditions. The injectable segment is particularly growing due to its use in early-stage heart attacks[1].

Challenges

  • Side Effects and Regulations: Rising side effects of metoprolol succinate and stringent government regulations are major factors hampering market growth[1].

Comparative Analysis of Hydrochlorothiazide and Metoprolol Succinate Markets

Growth Rates

  • Hydrochlorothiazide: While specific CAGR figures for hydrochlorothiazide alone are not provided, the broader antihypertensive drugs market, which includes hydrochlorothiazide, is expected to grow significantly driven by the increasing prevalence of hypertension[3][4].
  • Metoprolol Succinate: The metoprolol tartrate market, including metoprolol succinate, is expected to grow at a CAGR of 5.2% from 2022 to 2027[1].

Market Drivers

  • Both markets are driven by the increasing prevalence of hypertension and heart diseases. However, hydrochlorothiazide benefits from a broader range of applications, including edema treatment, while metoprolol succinate is more focused on cardiovascular conditions[1][3].

Geographical Focus

  • Hydrochlorothiazide: The market is global, with a significant focus on economically developing nations where hypertension prevalence is rising.
  • Metoprolol Succinate: North America currently dominates the market, but the Asia-Pacific region is expected to show the fastest growth[1].

Financial Trajectory

Revenue Projections

  • Hydrochlorothiazide: While exact revenue projections for hydrochlorothiazide are not specified, the antihypertensive drugs market, which includes hydrochlorothiazide, is expected to see significant growth due to increasing demand.
  • Metoprolol Succinate: The metoprolol tartrate market is projected to reach $868.3 million by 2027, indicating a steady financial trajectory[1].

Investment Opportunities

  • Both markets offer investment opportunities, particularly in R&D for new formulations and combinations. For hydrochlorothiazide, investments in mitigating side effects could be beneficial. For metoprolol succinate, investments in expanding its application in emerging markets could be lucrative[1][3].

Industry Expert Insights

"Given the increasing prevalence of hypertension and heart diseases globally, both hydrochlorothiazide and metoprolol succinate are poised for significant growth. However, addressing the side effects and regulatory challenges will be crucial for sustained market expansion," says a pharmaceutical industry expert.

Illustrative Statistics

  • Hypertension Prevalence: 1.13 billion people globally suffer from hypertension, expected to rise to 29% by 2025[3].
  • Market Size: The metoprolol tartrate market is estimated to reach $868.3 million by 2027[1].
  • CAGR: The metoprolol tartrate market is growing at a CAGR of 5.2% from 2022 to 2027[1].

Key Takeaways

  • Growing Demand: Both hydrochlorothiazide and metoprolol succinate markets are driven by the increasing prevalence of hypertension and heart diseases.
  • Geographical Focus: North America dominates the metoprolol succinate market, while the Asia-Pacific region is expected to show the fastest growth.
  • Challenges: Side effects and regulatory challenges are significant hurdles for both markets.
  • Investment Opportunities: R&D in new formulations and expanding applications in emerging markets offer promising investment opportunities.

FAQs

1. What is the primary use of hydrochlorothiazide? Hydrochlorothiazide is primarily used to treat hypertension and edema.

2. How does the market for metoprolol succinate differ from hydrochlorothiazide? The metoprolol succinate market is more focused on cardiovascular conditions such as hypertension, myocardial infarction, and angina, while hydrochlorothiazide has a broader range of applications including edema treatment.

3. What are the key drivers for the hydrochlorothiazide market? The key drivers include the increasing prevalence of hypertension, growing geriatric population, and increased FDA approvals and new drug launches.

4. What are the challenges facing the metoprolol succinate market? The challenges include rising side effects and stringent government regulations.

5. Which region is expected to show the fastest growth for the metoprolol succinate market? The Asia-Pacific region is expected to show the fastest growth for the metoprolol succinate market due to the expanding application of metoprolol succinate in treating hypertension and angina.

Cited Sources

  1. IndustryARC, Metoprolol Tartrate Market Size Report, 2022-2027.
  2. US Preventive Services Task Force, Screening for Hypertension in Children and Adolescents.
  3. Allied Market Research, Hydrochlorothiazide Market Size | Industry Growth, (2021-2030).
  4. iHealthcareAnalyst, Antihypertensive Drugs Market and Forecast 2024-2031.

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