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Last Updated: December 22, 2024

LEVONORDEFRIN; PROCAINE HYDROCHLORIDE; PROPOXYCAINE HYDROCHLORIDE - Generic Drug Details


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What are the generic sources for levonordefrin; procaine hydrochloride; propoxycaine hydrochloride and what is the scope of freedom to operate?

Levonordefrin; procaine hydrochloride; propoxycaine hydrochloride is the generic ingredient in one branded drug marketed by Eastman Kodak and is included in one NDA. Additional information is available in the individual branded drug profile pages.

Summary for LEVONORDEFRIN; PROCAINE HYDROCHLORIDE; PROPOXYCAINE HYDROCHLORIDE
US Patents:0
Tradenames:1
Applicants:1
NDAs:1
DailyMed Link:LEVONORDEFRIN; PROCAINE HYDROCHLORIDE; PROPOXYCAINE HYDROCHLORIDE at DailyMed

US Patents and Regulatory Information for LEVONORDEFRIN; PROCAINE HYDROCHLORIDE; PROPOXYCAINE HYDROCHLORIDE

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Eastman Kodak RAVOCAINE AND NOVOCAIN W/ NEO-COBEFRIN levonordefrin; procaine hydrochloride; propoxycaine hydrochloride INJECTABLE;INJECTION 008592-007 Approved Prior to Jan 1, 1982 DISCN No No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

LEVONORDEFRIN; PROCAINE HYDROCHLORIDE; PROPOXYCAINE HYDROCHLORIDE Market Analysis and Financial Projection Experimental

Market Dynamics and Financial Trajectory for Dental Anesthesia Drugs: Levonordefrin, Mepivacaine, and Other Local Anesthetics

Introduction

The dental anesthesia market is experiencing significant growth, driven by increasing dental health awareness, rising cases of dental problems, and advancements in healthcare infrastructure. This article will delve into the market dynamics and financial trajectory of key dental anesthesia drugs, including Levonordefrin, Mepivacaine, and other local anesthetics.

Global Dental Anesthesia Market Overview

The global dental anesthesia market was valued at USD 2.31 billion in 2024 and is projected to reach USD 3.76 billion by 2034, growing at a CAGR of 4.99% during this period[1][4].

Key Drivers of Market Growth

Rising Dental Health Issues

The increasing incidence of dental problems in both children and adults is a significant driver. Countries like China and India, with large populations and high DMFT (decayed, missing, and filled teeth) indices, are experiencing a heavy burden of dental and oral conditions, leading to greater demand for dental checkups and procedures[1][4].

Growing Oral Health Awareness

Enhanced awareness about oral health and the importance of regular dental visits are contributing to the market's growth. Government initiatives and improved access to healthcare facilities in regions like the Asia Pacific are also pivotal[1][4].

Aging Population

The rise in the geriatric population, who are more prone to chronic diseases and surgeries, is another key factor. By 2050, the proportion of the population above 60 years is expected to reach 22%, further driving the demand for dental anesthesia[3].

Regional Market Dynamics

Asia Pacific

The Asia Pacific region is expected to grow at the fastest CAGR, driven by favorable government initiatives, a large population, and advanced healthcare facilities. China and India are leading this growth, with the region accounting for more than 39% of the revenue share in 2023[1][4].

North America

North America dominates the local anesthesia drugs market, with a market share of 35.4% in 2023. This is attributed to the high prevalence of chronic diseases, a growing geriatric population, and improved healthcare infrastructure[3].

Levonordefrin: Market and Financial Insights

Role in Dental Anesthesia

Levonordefrin is a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions. It has pharmacologic activity similar to Epinephrine but is more stable. Levonordefrin is less potent than Epinephrine in raising blood pressure but is effective as a vasoconstrictor[2][5].

Market Impact

Levonordefrin, when combined with local anesthetics like Mepivacaine, extends the duration of anesthesia, making it a crucial component in dental procedures. The demand for such combinations is increasing due to the growing need for prolonged dental procedures[2].

Mepivacaine and Other Local Anesthetics

Mepivacaine

Mepivacaine, often used in combination with Levonordefrin, provides rapid onset and long-lasting anesthesia. It is metabolized primarily in the liver and excreted through the kidneys, with a duration of action ranging from 1 to 5.5 hours depending on the concentration and site of administration[2].

Market Share and Growth

Lidocaine currently dominates the local anesthesia market with a 28.7% market share in 2023. However, Ropivacaine is expected to register the fastest CAGR during the forecast period due to its favorable safety profile and longer duration of action[3].

Financial Trajectory

Market Size and Growth

The global dental anesthesia market is expected to grow from USD 2.31 billion in 2024 to USD 3.76 billion by 2034, at a CAGR of 4.99%. The local anesthesia drugs market, which includes dental anesthesia, was valued at USD 4.01 billion in 2023 and is projected to grow at a CAGR of 3.6% from 2024 to 2030[1][3].

Revenue Forecast

The Asia Pacific region, driven by China and India, is expected to contribute significantly to this growth. The region's market size is projected to increase from USD 900.90 million in 2024 to USD 1,485.20 million by 2034, growing at a CAGR of 5.13%[1].

Competitive Landscape

Key Players

Companies such as Dentsply Sirona, Laboratorios Inibsa, Pierre Pharma, Septodont, and others are key players in the dental anesthesia market. These companies are investing in research and development to improve the efficacy and safety of dental anesthesia products[4].

Application and Product Outlook

Injectable and Surface Anesthetics

The market is segmented into injectable and surface anesthetics. Injectable anesthetics, such as Mepivacaine and Lidocaine, dominate the market due to their widespread use in various dental procedures[3].

Product Innovations

Advancements in product formulations, such as the combination of local anesthetics with vasoconstrictors like Levonordefrin, are enhancing the market. These innovations improve the duration and efficacy of anesthesia, making them more appealing to dental professionals[2].

Regulatory and Government Initiatives

Favorable Government Policies

Government initiatives in regions like the Asia Pacific are supporting the growth of the dental anesthesia market. These policies include investments in healthcare infrastructure and public health campaigns to raise oral health awareness[1][4].

Challenges and Opportunities

Increasing Demand for Dental Procedures

The rising demand for dental procedures, including cosmetic and restorative surgeries, presents a significant opportunity for the dental anesthesia market. However, challenges such as the need for continuous innovation and regulatory compliance must be addressed[3][4].

Key Takeaways

  • The global dental anesthesia market is projected to grow significantly, driven by rising dental health issues and increasing oral health awareness.
  • The Asia Pacific region, particularly China and India, is expected to lead this growth.
  • Levonordefrin and Mepivacaine are crucial components in dental anesthesia, with Levonordefrin extending the duration of anesthesia when combined with local anesthetics.
  • The market is dominated by injectable anesthetics, with Lidocaine and Ropivacaine being key players.
  • Government initiatives and advancements in healthcare infrastructure are supporting market growth.

FAQs

What is the projected growth rate of the global dental anesthesia market from 2024 to 2034?

The global dental anesthesia market is expected to grow at a CAGR of 4.99% from 2024 to 2034[1].

Which region is expected to lead the growth in the dental anesthesia market?

The Asia Pacific region, particularly China and India, is expected to lead the growth in the dental anesthesia market due to favorable government initiatives and a large population[1][4].

What is the role of Levonordefrin in dental anesthesia?

Levonordefrin is used as a vasoconstrictor in local anesthetic solutions, extending the duration of anesthesia and reducing bleeding at the surgical site[2][5].

Which local anesthetic dominates the market?

Lidocaine currently dominates the local anesthesia market, accounting for a 28.7% market share in 2023[3].

What are the key drivers of the dental anesthesia market?

The key drivers include rising dental health issues, growing oral health awareness, and an increasing geriatric population[1][3][4].

Sources

  1. Precedence Research: Dental Anesthesia Market Size To Surpass USD 3.76 Bn By 2034
  2. Drugs.com: Mepivacaine and Levonordefrin: Package Insert / Prescribing Info
  3. Grand View Research: Local Anesthesia Drugs Market Size & Share Report, 2030
  4. Grand View Research: Dental Anesthesia Market Size & Share | Global Report, 2030
  5. DrugBank: Levonordefrin: Uses, Interactions, Mechanism of Action

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