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Last Updated: December 22, 2024

TECHNETIUM TC-99M SUCCIMER - Generic Drug Details


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What are the generic sources for technetium tc-99m succimer and what is the scope of freedom to operate?

Technetium tc-99m succimer is the generic ingredient in two branded drugs marketed by Theragnostics and Ge Healthcare, and is included in two NDAs. Additional information is available in the individual branded drug profile pages.

One supplier is listed for this compound.

Summary for TECHNETIUM TC-99M SUCCIMER
US Patents:0
Tradenames:2
Applicants:2
NDAs:2
Finished Product Suppliers / Packagers: 1
DailyMed Link:TECHNETIUM TC-99M SUCCIMER at DailyMed
Pharmacology for TECHNETIUM TC-99M SUCCIMER
Drug ClassLead Chelator
Mechanism of ActionLead Chelating Activity

US Patents and Regulatory Information for TECHNETIUM TC-99M SUCCIMER

Applicant Tradename Generic Name Dosage NDA Approval Date TE Type RLD RS Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Theragnostics NEPHROSCAN technetium tc-99m succimer POWDER;INTRAVENOUS 214993-001 Feb 18, 2022 RX Yes Yes ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
Ge Healthcare MPI DMSA KIDNEY REAGENT technetium tc-99m succimer kit INJECTABLE;INJECTION 017944-001 May 18, 1982 DISCN Yes No ⤷  Subscribe ⤷  Subscribe ⤷  Subscribe
>Applicant >Tradename >Generic Name >Dosage >NDA >Approval Date >TE >Type >RLD >RS >Patent No. >Patent Expiration >Product >Substance >Delist Req. >Exclusivity Expiration

TECHNETIUM TC-99M SUCCIMER Market Analysis and Financial Projection Experimental

Technetium-99m Market Dynamics and Financial Trajectory

Market Overview

The technetium-99m market, which includes radiopharmaceuticals like technetium Tc-99m succimer, is experiencing significant growth driven by several key factors.

Market Size and Growth

  • The technetium-99m market was valued at approximately USD 4.95 billion in 2023 and is expected to grow at a CAGR of 4.05% from 2024 to 2030, reaching nearly USD 6.54 billion by 2030[1][4].
  • Another estimate suggests the market will grow from USD 4,268.15 million in 2022 to USD 6,072.86 million by 2030, with a CAGR of 4.5% during this period[4].

Key Drivers

Increasing Demand for Diagnostic Procedures

  • The rising demand for Tc-99m-based radiopharmaceuticals, particularly for cardiovascular imaging, cancer detection, and other clinical applications, is a major driver of market growth. Technetium-99m is used in over 80% of all nuclear medicine procedures in the United States[1][4].

Advancements in Nuclear Imaging Techniques

  • Ongoing research and development in creating new Tc-99m-based radiopharmaceuticals with improved specificity and sensitivity are enhancing diagnostic accuracy and targeted imaging of various diseases, including cancer, cardiovascular disease, and neurological disorders[1][3].

Healthcare Infrastructure and Expenditure

  • The expansion of healthcare infrastructure, increased healthcare expenditure, and global health initiatives emphasizing innovative medical technologies are bolstering the demand for technetium-99m. Governments are implementing health programs to increase diagnostic imaging and treatment options[3][4].

Market Segmentation

Application Areas

  • The technetium-99m market is segmented into various applications such as cardiovascular imaging, bone scans, respiratory imaging, tumor imaging, and others. The cardiovascular segment holds the largest market share due to its critical role in myocardial perfusion imaging[1][4].

End Users

  • The market is segmented by end users into hospitals, diagnostic and imaging centers, and others. Diagnostic and imaging centers held the largest market share in 2022, while hospitals are expected to register the highest CAGR during the forecast period[4].

Regional Insights

  • North America, led by the United States and Canada, dominates the global technetium-99m market due to its advanced healthcare infrastructure and high prevalence of chronic diseases. Emerging markets like China are also presenting significant growth opportunities due to the development of healthcare infrastructure and the increasing demand for reliable diagnostic tools[1][4].

Challenges in the Supply Chain

  • The technetium-99m market faces challenges related to its complex and delicate supply chain. The production and distribution of Tc-99m rely on a just-in-time model, which is vulnerable to disruptions. The supply is closely linked to government-controlled enriched uranium, and financial struggles of older nuclear reactors that produce Tc-99m also pose significant challenges[1].

Technetium Tc-99m Succimer Specifics

Clinical Use

  • Technetium Tc-99m succimer is used as a diagnostic agent to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It is indicated for use in the scintigraphic evaluation of renal disorders in adults[2].

Pharmacokinetics and Radiation Safety

  • After administration, technetium Tc-99m succimer is distributed in the plasma, bound to plasma proteins, and concentrated in the kidneys. The radiation exposure to patients is relatively low, with estimated absorbed radiation doses provided for various organs and tissues[2].

Financial Trajectory

  • The growing demand for Tc-99m-based radiopharmaceuticals, driven by advancements in nuclear imaging and increasing diagnostic procedures, is expected to significantly increase the market size. The market is projected to grow steadily over the next several years, driven by the expanding use of technetium-99m in various clinical applications[1][3][4].

Key Takeaways

  • The technetium-99m market is driven by the increasing demand for diagnostic procedures and advancements in nuclear imaging techniques.
  • The market is segmented into various applications, with cardiovascular imaging holding the largest share.
  • North America dominates the market, but emerging markets like China are also showing significant growth potential.
  • Challenges in the supply chain, including the reliance on government-controlled enriched uranium and financial struggles of nuclear reactors, need to be addressed.
  • Technetium Tc-99m succimer plays a crucial role in renal disorder diagnostics, with a focus on its pharmacokinetics and radiation safety.

FAQs

What is the primary use of technetium Tc-99m in medical diagnostics?

Technetium Tc-99m is primarily used in nuclear medicine for various diagnostic procedures, including cardiovascular imaging, bone scans, respiratory imaging, and tumor imaging. It is used in over 80% of all nuclear medicine procedures in the United States[1].

What are the key drivers of the technetium-99m market growth?

The key drivers include the rising demand for Tc-99m-based radiopharmaceuticals, advancements in nuclear imaging techniques, expansion of healthcare infrastructure, and increased healthcare expenditure[1][3][4].

Which region dominates the global technetium-99m market?

North America, particularly the United States and Canada, dominates the global technetium-99m market due to its advanced healthcare infrastructure and high prevalence of chronic diseases[1].

What are the challenges faced by the technetium-99m market?

The market faces challenges related to its complex and delicate supply chain, reliance on government-controlled enriched uranium, and financial struggles of older nuclear reactors that produce Tc-99m[1].

How is technetium Tc-99m succimer used clinically?

Technetium Tc-99m succimer is used as a diagnostic agent to evaluate functional renal tissue and tubular function in patients with renal parenchymal disorders. It is indicated for use in the scintigraphic evaluation of renal disorders in adults[2].

Cited Sources:

  1. Maximize Market Research: Technetium-99m Market: Industry Analysis and Forecast 2030.
  2. FDA: HIGHLIGHTS OF PRESCRIBING INFORMATION - NEPHROSCAN.
  3. Transparency Market Research: Technetium-99m Market Size, Share, Growth & Overview, 2034.
  4. The Insight Partners: Technetium-99m Market Trends, Growth, Size, Share by 2030.

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