Drugs in MeSH Category Disinfectants

Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Exclusivity Expiration
Griffen	BIOSCRUB	chlorhexidine gluconate	SPONGE;TOPICAL	019822-001	Mar 31, 1989		OTC	No	No
Kendall Il	CHLORHEXIDINE GLUCONATE	chlorhexidine gluconate	SPONGE;TOPICAL	019490-001	Mar 27, 1987		DISCN	No	No
Matrix Medcl	STERI-STAT	chlorhexidine gluconate	SOLUTION;TOPICAL	070104-001	Jul 24, 1986		DISCN	No	No
Pharm Assoc	CHLORHEXIDINE GLUCONATE	chlorhexidine gluconate	SOLUTION;DENTAL	074522-001	Dec 15, 1995	AT	RX	No	No
Sage Prods	CHLORHEXIDINE GLUCONATE	chlorhexidine gluconate	CLOTH;TOPICAL	021669-001	Apr 25, 2005		OTC	Yes	Yes	7,427,574		Y
Xttrium	EXIDINE	chlorhexidine gluconate	SOLUTION;TOPICAL	019422-001	Dec 17, 1985		OTC	Yes	Yes

Disinfectants Market Analysis and Financial Projection

The global disinfectants market is experiencing robust growth driven by heightened health awareness, regulatory mandates, and technological innovations. This expansion is paralleled by a dynamic patent landscape marked by competitive filings, litigation, and shifts toward sustainable solutions. Below is a detailed analysis of market dynamics and intellectual property trends.

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Market Dynamics

Growth Projections

• The disinfectants market is projected to grow from $7.57 billion in 2024 to $14.41 billion by 2029 at a 14.6% CAGR, fueled by healthcare spending and aging populations[1].
• Specific segments, such as healthcare disinfectants and sanitizers, are expected to surge from $16.8 billion in 2024 to $39.01 billion by 2033 (9.21% CAGR)[13].

Key Drivers

1. Healthcare Expenditure: Rising healthcare spending ($4.5 trillion in the U.S. in 2022[1]) amplifies demand for infection control in hospitals and laboratories.
2. Pandemic Impact: COVID-19 accelerated adoption in hospitality, food processing, and residential sectors, with products like Lysol’s EPA-approved air sanitizer[7][10].
3. Antimicrobial Resistance (AMR): Increasing pathogen resistance drives demand for advanced formulations[4][16].
4. Regulatory Compliance: Stringent hygiene standards in healthcare and food industries mandate effective disinfection[10][13].

Trends and Innovations

• Eco-Friendly Solutions: Non-toxic and biodegradable disinfectants are gaining traction. For example, SC Johnson’s alcohol-based formulations target emerging pathogens like monkeypox[10].
• UV and Light-Based Technologies: Innovations include illumiPure’s CleanWhite® LED, which eliminates 99% of pathogens using white light[5], and Xenex Disinfection Services’ UV robots[2].

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Patent Landscape

Key Players and Technologies

1. Xenex Disinfection Services: Holds 24 patents for UV disinfection robots, though over 100 U.S. patents reference UV disinfection, reflecting a crowded field[2][8].
2. illumiPure: Secured a global patent for CleanWhite® LED, emphasizing safe, continuous disinfection in occupied spaces[5].
3. Chlorhexidine Gluconate: Protected by patents expiring in 2026–2027, with applications in alcohol-free disinfection systems[11][15].

Litigation and Challenges

• Neister’s UV Patent: The ’605 patent for multi-wavelength UV disinfection was invalidated in 2024 due to prior art, highlighting risks in overlapping technologies[8].
• Competition: Amazon’s entry into UV robot development intensifies market competition[2].

Regional and Sectoral Focus

• North America Dominates: Accounts for the largest market share due to advanced healthcare infrastructure and key players like 3M and Ecolab[13].
• Asia-Pacific Growth: Emerging economies prioritize healthcare modernization, driving demand[13].

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MeSH Classification and Biomedical Applications

The NLM MeSH Class D27.505.954.122.425 defines disinfectants as agents for inanimate surfaces, distinct from antiseptics[12]. Key subcategories include:

• Chemical Disinfectants: Quaternary ammonium compounds and alcohol-based solutions dominate[7].
• UV and Light-Based Systems: Patented technologies address limitations of traditional chemicals[2][5].
• Biocides: Broad-spectrum agents critical for hospital equipment sterilization[12].

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Future Outlook

• Sustainability: Demand for green disinfectants will grow, with R&D focusing on reducing environmental impact[7][16].
• Pathogen-Specific Solutions: Tailored formulations for drug-resistant infections and viruses will emerge[4][14].
• Regulatory Evolution: Policies may adapt to balance IP protection with public health needs, particularly post-pandemic[6][8].

“Innovations like UV disinfection and eco-friendly formulations are reshaping the market, but patent challenges underscore the need for novel, non-obvious technologies.”[8][16]

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Key Takeaways

• The disinfectants market is expanding rapidly due to health crises and regulatory pressures.
• UV and LED technologies are patent battlegrounds, with litigation shaping competitive landscapes.
• Sustainability and pathogen-specific efficacy will drive next-generation product development.

FAQs

1. What is fueling disinfectant market growth?
   Rising healthcare spending, pandemics, and antimicrobial resistance.
2. How does UV disinfection impact patents?
   High competition and prior art risks, as seen in Neister’s invalidated patent.
3. Which regions lead the market?
   North America dominates, while Asia-Pacific shows fastest growth.
4. What distinguishes disinfectants from antiseptics?
   Disinfectants target inanimate surfaces; antiseptics are for living tissues[12].
5. Are eco-friendly disinfectants viable?
   Yes, with innovations like Lysol’s air sanitizer and alcohol-free formulations gaining traction[7][11].

References

1. https://www.thebusinessresearchcompany.com/report/disinfectants-global-market-report
2. https://www.keionline.org/33023
3. https://en.wikipedia.org/wiki/List_of_MeSH_codes_(D27)
4. https://www.globenewswire.com/news-release/2024/10/17/2964843/32656/en/Antiseptic-and-Disinfectant-Market-Size-to-Hit-USD-61-2-billion-by-2031-at-7-0-CAGR-Report-by-Transparency-Market-research-Inc.html
5. https://www.newswire.com/news/illumipure-receives-worldwide-patent-on-innovative-cleanwhite-led-21842332
6. https://re.public.polimi.it/retrieve/e0c31c12-dca4-4599-e053-1705fe0aef77/11311-1202990_Barbieri.pdf
7. https://www.gminsights.com/industry-analysis/surface-disinfectant-market
8. https://www.quantadose.com/the-fall-of-a-patent-s-edward-neister-loses-case-on-far-uvc-disinfection-technology/
9. https://www.ncbi.nlm.nih.gov/sites/entrez?Db=mesh&Cmd=DetailsSearch&Term=%22Glutaral%22%5BMeSH+Terms%5D
10. https://www.globenewswire.com/news-release/2024/12/14/2997128/0/en/Surface-Disinfectant-Market-to-Reach-USD-10-3-Billion-by-2032-Driven-by-Rising-Demand-for-Healthcare-Applications-Report-by-SNS-Insider.html
11. https://pharsight.greyb.com/drug/chlorhexidine-gluconate-patent-expiration
12. https://meshb.nlm.nih.gov/record/ui?ui=D004202
13. https://straitsresearch.com/report/healthcare-disinfectants-and-sanitizers-market
14. https://pmc.ncbi.nlm.nih.gov/articles/PMC8912343/
15. https://www.drugpatentwatch.com/p/patent/7935093
16. https://www.coherentmarketinsights.com/market-insight/disinfectants-market-256