Claims for Patent: 10,034,841

Summary for Patent: 10,034,841

Title:	Transdermal therapeutic system comprising an adhesive layer method for siliconizing the back layer of the system and use of said back layer
Abstract:	The invention generally relates to a transdermal therapeutic system which comprises a backing layer, an adhesive layer, a polymer layer and a removable protective layer. The adhesive layer is an organosiloxane layer that is anchored to the backing layer by siliconization.
Inventor(s):	Muller; Walter (Andernach, DE), Leonhard; Johannes (Bendorf, DE)
Assignee:	LTS Lohmann Therapie-Systeme AG (Andernach, DE)
Application Number:	14/953,789
Patent Claims:	1. A transdermal therapeutic system comprising in spatial order (a) a backing layer, (b) a siliconized anchor layer, and (c) a polymer layer comprising at least one silicone adhesive acid active ingredient, wherein said siliconized anchor layer (b) (i) is firmly anchored to the backing layer (a), (ii) adheres to the polymer layer (c), (iii) comprises organopolysiloxanes containing vinyl groups crosslinked with organopolysiloxanes containing Si--H groups, and (iv) has a thickness of less than 10 micrometers. 2. The transdermal therapeutic system as claimed in claim 1, wherein the backing layer is a polymeric film material selected from the group consisting of polyesters, polypropylene, polyethylene, polyurethane, EVA layers in combination with polyester, polyvinylidene chloride, polyaramids, and ethylene-(meth)acrylate copolymer. 3. A transdermal therapeutic system as claimed in claim 2, wherein the polymeric film material is polyethylene terephthalate. 4. The transdermal therapeutic system as claimed in claim 1, wherein the backing layer comprises a material selected from the group consisting of ethylcellulose, cellulose acetate, cellophane, paper, metal-polymer composite, and ethylene-vinyl acetate copolymers. 5. The transdermal therapeutic system as claimed in claim 1, wherein the silicone adhesive is selected from the group consisting of polysiloxanes and polysiloxane mixtures. 6. A transdermal therapeutic system as claimed in claim 1, wherein said polymer layer (c) is self-adhesively connected to the siliconized anchor layer (b). 7. A transdermal therapeutic system as claimed in claim 1, wherein said system further comprises a detachable protective layer. 8. A transdermal therapeutic system as claimed in claim 1, wherein said siliconized anchor layer absorbs no active ingredient. 9. A transdermal therapeutic system as claimed in claim 1, wherein said backing layer is polar, said polymer layer consists of silicone adhesive, and said adhesive does not extend past said transdermal therapeutic system. 10. A transdermal therapeutic system as claimed in claim 1, wherein said siliconized anchor layer consists of organopolysiloxanes containing vinyl groups and organopolysiloxanes containing Si--H groups. 11. The transdermal therapeutic system as claimed in claim 1, wherein said polymer layer (c) adheres to said detachable protective layer.