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Last Updated: December 15, 2024

Claims for Patent: 10,034,879

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Summary for Patent: 10,034,879

Title:	Substituted benzaldehyde compounds and methods for their use in increasing tissue oxygenation
Abstract:	Provided are substituted benzaldehydes and derivatives thereof that act as allosteric modulators of hemoglobin, methods and intermediates for their preparation, pharmaceutical compositions comprising the modulators, and methods for their use in treating disorders mediate by hemoglobin and disorders that would benefit from increased tissue oxygenation.
Inventor(s):	Metcalf; Brian (South San Francisco, CA), Chuang; Chihyuan (South San Francisco, CA)
Assignee:	Global Blood Therapeutics, Inc. (South San Francisco, CA)
Application Number:	15/852,406
Patent Claims:	1. A compound having the structure: ##STR00161## 2. A solid dosage form comprising a compound having the structure: ##STR00162## and a pharmaceutically acceptable excipient.

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