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Last Updated: September 1, 2024

Claims for Patent: 10,059,714


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Summary for Patent: 10,059,714
Title:Protein kinase B inhibitors
Abstract:The invention relates to a novel group of compounds of Formula (I) or salts thereof:
Inventor(s):Johnson Paul David, Leach Andrew, Luke Richard William Arthur, Matusiak Zbigniew Stanley, Morris Jeffrey James
Assignee:AstraZeneca AB
Application Number:US15351481
Patent Claims: 3. A compound according to wherein Rrepresents —(CH)—R claim 1 , p represents 1 claim 1 , 2 or 3 claim 1 , Ris selected from phenyl claim 1 , piperidinyl claim 1 , piperazinyl claim 1 , pyrrolidinyl claim 1 , morpholinyl claim 1 , imidazolyl claim 1 , isoxazolyl claim 1 , pyrazolyl and thiazolyl and Ris optionally substituted by a single methyl group.4. A compound according to claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Rrepresents hydroxyethyl.5. A compound according to claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Rrepresents chloro or bromo.6. A compound according to claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein Rrepresents hydrogen.7. A compound according to claim 1 , or a pharmaceutically acceptable salt thereof claim 1 , wherein n is 0 or 1.8. A pharmaceutical composition comprising a compound according to claim 1 , or a pharmaceutically-acceptable salt thereof claim 1 , together with a pharmaceutically acceptable diluent or carrier.

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