Claims for Patent: 10,076,615

Summary for Patent: 10,076,615

Title:	Nasal delivery
Abstract:	A nasal delivery device for and method of delivering substance to a nasal cavity of a subject, the delivery device comprising: a nosepiece for fitting to a nostril of a subject, wherein the nosepiece comprises a tip element which includes a delivery aperture from which substance is in use delivered into the nasal cavity, and the tip element is at least in part tapered such as to be inclined to a longitudinal axis of the nosepiece, with the delivery aperture extending both laterally across the tip element and along a longitudinal extent of the tip element; a nozzle through which substance is in use delivered, preferably substantially axially to a longitudinal axis of the nosepiece, to the respective nasal cavity; and a delivery unit for delivering substance through the nozzle of the nosepiece.
Inventor(s):	Djupesland; Per Gisle (Oslo, NO), Sheldrake; Colin David (Wiltshire, GB)
Assignee:	OptiNose AS (Oslo, NO)
Application Number:	14/618,273
Patent Claims:	1. A method of fitting a nasal delivery device to a nostril of a subject, the method comprising: inserting a nosepiece of the nasal delivery device into one of the nostrils of the subject, with the nasal delivery device having a first alignment; twisting the nosepiece in the nostril so as to rotate the nasal delivery device to have a second alignment which is different from the first alignment and in which a mouthpiece of the nasal delivery device is aligned with a mouth of the subject; sealing a nare of the nostril against the nosepiece; and causing the subject to exhale through the mouthpiece. 2. The method of claim 1, further comprising: applying a grip-enhancing agent to an exterior surface of a nose of the subject. 3. The method of claim 1, wherein the nosepiece comprises a tip element. 4. The method of claim 3, wherein the tip element is substantially elliptical. 5. The method of claim 3, wherein the tip element is substantially rectangular. 6. The method of claim 3, wherein the tip element comprises a delivery aperture. 7. The method of claim 3, wherein the tip element is tapered. 8. The method of claim 1, wherein the nasal delivery device comprises a substance supply unit and a nose gripping member. 9. The method of claim 8, wherein the nose gripping member is tethered to a body of the nasal delivery device. 10. The method of claim 8, wherein the nose gripping member comprises a gripping element which is configured to be fixed to a nose of the subject. 11. The method of claim 1, further comprising; pressing a finger against the skin of the nose so as to press the nare of the nostril against the nosepiece. 12. The method of claim 1, further comprising: pulling the nare of the nostril over the nosepiece. 13. The method of claim 12, wherein the pulling is done by a finger.