Claims for Patent: 10,112,903
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Summary for Patent: 10,112,903
| Title: | Heterocyclic compounds for the treatment of neurological and psychological disorders |
| Abstract: | Lactam compounds of Formula I and their use for the treatment of neurological and psychiatric disorders including schizophrenia, bipolar disorder, anxiety disorder and insomnia is disclosed. ##STR00001## |
| Inventor(s): | Remenar; Julius F. (Framingham, MA), Blumberg; Laura Cook (Lincoln, MA), Zeidan; Tarek A. (Watertown, MA) |
| Assignee: | ALKERMES PHARMA IRELAND LIMITED (Dublin, IE) |
| Application Number: | 15/875,478 |
| Patent Claims: |
1. A compound having the formula: ##STR00949## or a pharmaceutically acceptable salt or solvate thereof.
2. A compound having the formula: ##STR00950## 3. A pharmaceutical composition comprising the compound of claim 1, and one or more pharmaceutically acceptable carriers or excipients. 4. A pharmaceutical composition comprising the compound of claim 2, and one or more pharmaceutically acceptable carriers or excipients. 5. A method of treating schizophrenia comprising administering the compound of claim 1 to a patient in need thereof. 6. A method of treating bipolar disorder comprising administering the compound of claim 1 to a patient in need thereof. 7. A method of treating depression comprising administering the compound of claim 1 to a patient in need thereof. 8. A method of treating mania comprising administering the compound of claim 1 to a patient in need thereof. 9. A method of treating anxiety comprising administering the compound of claim 1 to a patient in need thereof. 10. A method of treating schizophrenia comprising administering a compound having the formula: ##STR00951## to a patient in need thereof. 11. A method of treating bipolar disorder comprising administering a compound having the formula: ##STR00952## to a patient in need thereof. 12. A method of treating depression comprising administering the compound of claim 2 to a patient in need thereof. 13. A method of treating mania comprising administering the compound of claim 2 to a patient in need thereof. 14. A method of treating anxiety comprising administering the compound of claim 2 to a patient in need thereof. 15. A method of treating schizophrenia comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof. 16. A method of treating bipolar disorder comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof. 17. A method of treating depression comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof. 18. A method of treating mania comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof. 19. A method of treating anxiety comprising administering the pharmaceutical composition of claim 3 to a patient in need thereof. 20. A method of treating schizophrenia comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof. 21. A method of treating bipolar disorder comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof. 22. A method of treating depression comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof. 23. A method of treating mania comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof. 24. A method of treating anxiety comprising administering the pharmaceutical composition of claim 4 to a patient in need thereof. |
